Click here to switch to the map view.

The map label for this gene is moaB [H]

Identifier: 87199795

GI number: 87199795

Start: 1875277

End: 1875804

Strand: Reverse

Name: moaB [H]

Synonym: Saro_1778

Alternate gene names: 87199795

Gene position: 1875804-1875277 (Counterclockwise)

Preceding gene: 87199796

Following gene: 87199794

Centisome position: 52.67

GC content: 64.2

Gene sequence:

>528_bases
GTGGCAATTGATCCCTCCCGCGAATTCAAGCCTATCAACATCGCCCTGCTGACCGTCTCCGACACCCGTGGCCCTGACGA
GGACACCTCTGGCGACATCCTCGCTGAACGCATCCGCGCAAAGGGCCACAAGCTGGCCGCCCGCGCGATGGAAAAGGACG
ATGCGGACCGTATCGTCAGCCGGCTCAACAACTGGGTCGACGATCGTTCGGTCGACGCGGTGATCATCACCGGCGGGACC
GGCCTTACCGGACGCGACGTGACGCCCGAGGCGCTCGACCGCGTGAAGACGCGTGAGATCCCGGGCTTCGGCGAACTGTT
CCGCTGGCTGTCCTACAAGACCATCGGCACCAGCACGATCCAGTCGCGCGCCTGCGCGGTCGTCGCGCGCGGCACCTATA
TCTTTGCCCTCCCGGGATCGAACGGTGCGGTAAAGGACGGGTGGGACGGGATTCTCGACGAACAGCTCGACAGCCGCAAC
CGGCCCTGCAATTTCGTCGAACTGATGCCGAGGCTCCTCGAGAAATAG

Upstream 100 bases:

>100_bases
CAGGCGGGCGGCCCGTCCGACAGCCGGCTCGGCCTCGTCCAGGGCATGTGGCCGAAGTTCCCGGGCCTTGCGGGAGCGGA
CAACGTAAGGATCGCTTCGC

Downstream 100 bases:

>100_bases
TTCCGGATCGGACCCTTCGTCCGAAATCCACATTTGATCCATCATCGCCGCATACGTCCGTCGCAGGATTTCGTGACGGG
AGAGATGGACTGTGGTGGCA

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MAIDPSREFKPINIALLTVSDTRGPDEDTSGDILAERIRAKGHKLAARAMEKDDADRIVSRLNNWVDDRSVDAVIITGGT
GLTGRDVTPEALDRVKTREIPGFGELFRWLSYKTIGTSTIQSRACAVVARGTYIFALPGSNGAVKDGWDGILDEQLDSRN
RPCNFVELMPRLLEK

Sequences:

>Translated_175_residues
MAIDPSREFKPINIALLTVSDTRGPDEDTSGDILAERIRAKGHKLAARAMEKDDADRIVSRLNNWVDDRSVDAVIITGGT
GLTGRDVTPEALDRVKTREIPGFGELFRWLSYKTIGTSTIQSRACAVVARGTYIFALPGSNGAVKDGWDGILDEQLDSRN
RPCNFVELMPRLLEK
>Mature_174_residues
AIDPSREFKPINIALLTVSDTRGPDEDTSGDILAERIRAKGHKLAARAMEKDDADRIVSRLNNWVDDRSVDAVIITGGTG
LTGRDVTPEALDRVKTREIPGFGELFRWLSYKTIGTSTIQSRACAVVARGTYIFALPGSNGAVKDGWDGILDEQLDSRNR
PCNFVELMPRLLEK

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=31.5068493150685, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=31.5068493150685, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1787000, Length=160, Percent_Identity=49.375, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1786190, Length=103, Percent_Identity=38.8349514563107, Blast_Score=70, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17136978, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24638841, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19287; Mature: 19156

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDPSREFKPINIALLTVSDTRGPDEDTSGDILAERIRAKGHKLAARAMEKDDADRIVS
CCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
RLNNWVDDRSVDAVIITGGTGLTGRDVTPEALDRVKTREIPGFGELFRWLSYKTIGTSTI
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHH
QSRACAVVARGTYIFALPGSNGAVKDGWDGILDEQLDSRNRPCNFVELMPRLLEK
HHHHEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AIDPSREFKPINIALLTVSDTRGPDEDTSGDILAERIRAKGHKLAARAMEKDDADRIVS
CCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
RLNNWVDDRSVDAVIITGGTGLTGRDVTPEALDRVKTREIPGFGELFRWLSYKTIGTSTI
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHH
QSRACAVVARGTYIFALPGSNGAVKDGWDGILDEQLDSRNRPCNFVELMPRLLEK
HHHHEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]