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The map label for this gene is prmA [H]

Identifier: 87199759

GI number: 87199759

Start: 1836751

End: 1837707

Strand: Reverse

Name: prmA [H]

Synonym: Saro_1742

Alternate gene names: 87199759

Gene position: 1837707-1836751 (Counterclockwise)

Preceding gene: 87199760

Following gene: 87199758

Centisome position: 51.6

GC content: 71.26

Gene sequence:

>957_bases
ATGAGCTGGAAAGTTACCGTGTTCGCGCCGCGCGACGAGGTCCAGGCGGCGCTCGTCGCGCATGAGGACGCGTGGGACTG
GGACCACGACATCGTCATCGCCGGCAGCGAGATCGCGGAGGACAAGCCGGAGGACTGGCAGCTCGAGGCGTGGCTCGACC
GCAAGCCGACCAAGGCCGACCGGAACGCGATCGCGGACCTGTTCGAGGGCGCACCGCCCAAACTGAACGTCGAGAAGCTG
CCGGACGCCGACTGGGTCACGCTCAGCCAGCAAGGCGTCGAGCCGATCCGCGAGGGCGCCTTCCACGTCCACACACCCGA
GTACCCGCCACTGGCGCAAGCCGGCGTGCGCGACTTCGTGATCCCCGCAAGCCAGGCGTTCGGCACCGGCCAGCACGCGA
CGACCGCGGGGTGCCTGGCGATGCTGACCCACATGAAGCGGCAGGGCATCCTGGTGCGCAACCTTGCGGACATCGGCACC
GGCACAGGCCTGCTCGCCTTCGCCGGCCTGCACCTGTGGCCCTCCGCCCGCGCCATCGCCAGCGACATCGACGCGGTCTG
CGGGCCGGTGGTGGCGGAGAACGCGGCCAACAACGGCATTGCACTGGGCGACGGACCGGGGCGCATGGCCATGGTCATCG
CGGCCGGCATGGAGCATCCGCTGTTGCAGGCGGCCGGACCATACGACCTGCTCATCGCCAACATCCTGGCGGGGCCGCTC
GTCGAACTGGCCCCCGAGTTCGCCCGCGCGGTGGTGCCGGGTGGAAGCATCCTGCTGGCCGGGCTCCTCGAGACGCAGGA
GGCGGCCGTGCGCGCCGCCTACCGCAAGGCCGGCCTCAGGCTGGCGGCACGGATGGTTCGCGGCGACTGGTCGATCCTGT
GGCTGCGCCGCCGGAGCGCTGGCGGCGTGCGGTCGAGCCGAGTCGGGGCCTTGCCGGAGTGGTCCAAGCGGTGGTGA

Upstream 100 bases:

>100_bases
TGTTCGAGCGGATGAGCGCAGAGCGCCGCCTCGACGAGCCCGGCGCCTGCAAGGCACTGGCCGCCGGAGCGCGCGACCGT
CTTGAAAAGGCACTGGCACA

Downstream 100 bases:

>100_bases
ACCGTTCAGGTTGCGCCCGATCGGCCTGAACAGGTTTACGGGGTTTACACAGTCCAGGAGAACTTTCGCGAGGCCCGCGA
CCCACGCCTTTGCGATGCGA

Product: 50S ribosomal protein L11P methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSWKVTVFAPRDEVQAALVAHEDAWDWDHDIVIAGSEIAEDKPEDWQLEAWLDRKPTKADRNAIADLFEGAPPKLNVEKL
PDADWVTLSQQGVEPIREGAFHVHTPEYPPLAQAGVRDFVIPASQAFGTGQHATTAGCLAMLTHMKRQGILVRNLADIGT
GTGLLAFAGLHLWPSARAIASDIDAVCGPVVAENAANNGIALGDGPGRMAMVIAAGMEHPLLQAAGPYDLLIANILAGPL
VELAPEFARAVVPGGSILLAGLLETQEAAVRAAYRKAGLRLAARMVRGDWSILWLRRRSAGGVRSSRVGALPEWSKRW

Sequences:

>Translated_318_residues
MSWKVTVFAPRDEVQAALVAHEDAWDWDHDIVIAGSEIAEDKPEDWQLEAWLDRKPTKADRNAIADLFEGAPPKLNVEKL
PDADWVTLSQQGVEPIREGAFHVHTPEYPPLAQAGVRDFVIPASQAFGTGQHATTAGCLAMLTHMKRQGILVRNLADIGT
GTGLLAFAGLHLWPSARAIASDIDAVCGPVVAENAANNGIALGDGPGRMAMVIAAGMEHPLLQAAGPYDLLIANILAGPL
VELAPEFARAVVPGGSILLAGLLETQEAAVRAAYRKAGLRLAARMVRGDWSILWLRRRSAGGVRSSRVGALPEWSKRW
>Mature_317_residues
SWKVTVFAPRDEVQAALVAHEDAWDWDHDIVIAGSEIAEDKPEDWQLEAWLDRKPTKADRNAIADLFEGAPPKLNVEKLP
DADWVTLSQQGVEPIREGAFHVHTPEYPPLAQAGVRDFVIPASQAFGTGQHATTAGCLAMLTHMKRQGILVRNLADIGTG
TGLLAFAGLHLWPSARAIASDIDAVCGPVVAENAANNGIALGDGPGRMAMVIAAGMEHPLLQAAGPYDLLIANILAGPLV
ELAPEFARAVVPGGSILLAGLLETQEAAVRAAYRKAGLRLAARMVRGDWSILWLRRRSAGGVRSSRVGALPEWSKRW

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=222, Percent_Identity=31.981981981982, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34107; Mature: 33976

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKVTVFAPRDEVQAALVAHEDAWDWDHDIVIAGSEIAEDKPEDWQLEAWLDRKPTKAD
CCEEEEEECCHHHHHHHHHCCCCCCCCCCCEEEECCHHCCCCCCCCEEEEECCCCCCHHH
RNAIADLFEGAPPKLNVEKLPDADWVTLSQQGVEPIREGAFHVHTPEYPPLAQAGVRDFV
HHHHHHHHCCCCCCCCHHHCCCCCEEEECHHCCHHHHCCCEEEECCCCCCHHHHCCHHEE
IPASQAFGTGQHATTAGCLAMLTHMKRQGILVRNLADIGTGTGLLAFAGLHLWPSARAIA
CCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHH
SDIDAVCGPVVAENAANNGIALGDGPGRMAMVIAAGMEHPLLQAAGPYDLLIANILAGPL
HHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHH
VELAPEFARAVVPGGSILLAGLLETQEAAVRAAYRKAGLRLAARMVRGDWSILWLRRRSA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GGVRSSRVGALPEWSKRW
CCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SWKVTVFAPRDEVQAALVAHEDAWDWDHDIVIAGSEIAEDKPEDWQLEAWLDRKPTKAD
CEEEEEECCHHHHHHHHHCCCCCCCCCCCEEEECCHHCCCCCCCCEEEEECCCCCCHHH
RNAIADLFEGAPPKLNVEKLPDADWVTLSQQGVEPIREGAFHVHTPEYPPLAQAGVRDFV
HHHHHHHHCCCCCCCCHHHCCCCCEEEECHHCCHHHHCCCEEEECCCCCCHHHHCCHHEE
IPASQAFGTGQHATTAGCLAMLTHMKRQGILVRNLADIGTGTGLLAFAGLHLWPSARAIA
CCCHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHH
SDIDAVCGPVVAENAANNGIALGDGPGRMAMVIAAGMEHPLLQAAGPYDLLIANILAGPL
HHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHH
VELAPEFARAVVPGGSILLAGLLETQEAAVRAAYRKAGLRLAARMVRGDWSILWLRRRSA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GGVRSSRVGALPEWSKRW
CCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]