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The map label for this gene is ykoH [H]

Identifier: 87199649

GI number: 87199649

Start: 1707602

End: 1709143

Strand: Reverse

Name: ykoH [H]

Synonym: Saro_1632

Alternate gene names: 87199649

Gene position: 1709143-1707602 (Counterclockwise)

Preceding gene: 87199651

Following gene: 87199648

Centisome position: 47.99

GC content: 62.26

Gene sequence:

>1542_bases
GTGAATGCGCTCCGCCTTAAGCTGTGGATGACGCTCGCCTTCGTCATGCTGACAGTGGCAGTGCCCGGCGTTATCGCGCG
CCATGCGCTCGGCGTCGTACGCGCACAGCATGCCCGCTCCGAAGCCTCATCCCAGTCGCTCAGCGCATTCCAGCGCCTCG
CCGTGCTCGGCTACACGCTGCAGCAGGAACGCTACGTCGATCCGGAAGGCTTTGCGAAGGACCGCCTGCTGTACATCGAC
GGAGTCCGTTCGCACGTCACAAATGCTGAACGGTACATCAATGCCGAAATCCGCCTGATCAGCGAAACCCCGCTCGATCG
CCGCAACCGGGCCAAATCCATCGAGGAAGAAGTCAAGCAGCGGGCGAAGCTTCACGTGATCGGGGCCAACCTGGAAAAGT
CGCTCATGGGCGACGGCCGGGAGACTCTGTGGGAAGACCTAGTCTTCGAAGCCATCAAGGTCGAAGAACGCGAAGCAAAG
GAATACCAGCGCAGCTCCATCGAAACCTTCCAGAGCGTGTCCGACACCCTGTTCCTTACGGTGTCGGTCGTTGGCATATT
CGGCATTCTTGCCCTCATATGGGGTCAGCGCCAGGTCATCCGCCCGCTCGGCGCATTGTGGCGCGGCACGCGGGAAATGG
CCGAAGGCCGCTACGATCGCCGCGTCCCGGTCGTCGGCACAACCGAGTTTCGTACCATCGCCAACAGCTTCAACACGATG
GCCGCGCGCGTCGAAGAAGCCGCCTTGTCGATGCAGCGTACGAACGAGGAACTGGAACGTGCGGTTGCGCGCCGGACATC
CGAACTCGCCACGACCAACCGCTCCCTCGAACGGGCGAACCGGCTGCGGCGGCAATTCCTGGCCGATGCCAGCCACGAAT
TGCGCACGCCCCTGTCGATCATGCGCAGCGAAGCCGAAATCACACTGCGCAAGGCGGATGCGGACATGGACGAACTCAGG
ACCGGGCTCGACCGCGTGGTTCGGCTTTCCGCGCTCATGGCCGAAATGATCGAAGACATGTTGCAGGTCGCCCGTGCCGA
AGAGCCGATGCTGCAGACCGTCATCGCGCCATTCGATGTGGTTGCCGCAACACGCACCTGCATCGACGATTTCCACCGCG
TGATCGAGGATGATGGCGGACAGATCATCCTGACCGAATGCCCCGATGCACTGATCGTCGAAGGCGATGCGGTCCGCCTG
CAACAGGTGATCCGCATCGTCGTGGACAATGCCGTGTGCTATTCCTCACATGCACCTCACGTGGAAGTCGCTATCCGTCA
GGAAGAGGGCGACGCGGTAATCGAGGTGTCGGACCAGGGGGACGGCATCCCCGCCGAAGACATTCCCCACCTGTTCCAGC
GCTTCCGTCGCGGCAGCCGCAAAGTCGGCAGTGGCCAGGGCCTCGGCCTTTCCATTGCCAGGTCCATTCTGGAAGCGCTC
GGTGGCACGATCAGCCTAGAGAGCCGGCTCCATGAAGGAACCCGGGTATCGATACGTCTCCCCCTCCCGCCAAGCGGGAC
GGCACATGGAATCATCGCATGA

Upstream 100 bases:

>100_bases
GTCTTGAAGTGCGGCGCCTTCTGCTGGCTGTGTCTGGTCAGAGCGTTCGGCCGCCTTGCGGACCCGTCGGGGCGCGGATC
CAGCGGCAGAGGTCCATCTC

Downstream 100 bases:

>100_bases
GAATACTCATCATCGAGGACGAGATCGAACTGGCGGGTGCCTTGCACCGTGGCCTTACCCAGGAAGGCTGCAAGGTCACC
CTCGCGACCGACGGCTCCAC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MNALRLKLWMTLAFVMLTVAVPGVIARHALGVVRAQHARSEASSQSLSAFQRLAVLGYTLQQERYVDPEGFAKDRLLYID
GVRSHVTNAERYINAEIRLISETPLDRRNRAKSIEEEVKQRAKLHVIGANLEKSLMGDGRETLWEDLVFEAIKVEEREAK
EYQRSSIETFQSVSDTLFLTVSVVGIFGILALIWGQRQVIRPLGALWRGTREMAEGRYDRRVPVVGTTEFRTIANSFNTM
AARVEEAALSMQRTNEELERAVARRTSELATTNRSLERANRLRRQFLADASHELRTPLSIMRSEAEITLRKADADMDELR
TGLDRVVRLSALMAEMIEDMLQVARAEEPMLQTVIAPFDVVAATRTCIDDFHRVIEDDGGQIILTECPDALIVEGDAVRL
QQVIRIVVDNAVCYSSHAPHVEVAIRQEEGDAVIEVSDQGDGIPAEDIPHLFQRFRRGSRKVGSGQGLGLSIARSILEAL
GGTISLESRLHEGTRVSIRLPLPPSGTAHGIIA

Sequences:

>Translated_513_residues
MNALRLKLWMTLAFVMLTVAVPGVIARHALGVVRAQHARSEASSQSLSAFQRLAVLGYTLQQERYVDPEGFAKDRLLYID
GVRSHVTNAERYINAEIRLISETPLDRRNRAKSIEEEVKQRAKLHVIGANLEKSLMGDGRETLWEDLVFEAIKVEEREAK
EYQRSSIETFQSVSDTLFLTVSVVGIFGILALIWGQRQVIRPLGALWRGTREMAEGRYDRRVPVVGTTEFRTIANSFNTM
AARVEEAALSMQRTNEELERAVARRTSELATTNRSLERANRLRRQFLADASHELRTPLSIMRSEAEITLRKADADMDELR
TGLDRVVRLSALMAEMIEDMLQVARAEEPMLQTVIAPFDVVAATRTCIDDFHRVIEDDGGQIILTECPDALIVEGDAVRL
QQVIRIVVDNAVCYSSHAPHVEVAIRQEEGDAVIEVSDQGDGIPAEDIPHLFQRFRRGSRKVGSGQGLGLSIARSILEAL
GGTISLESRLHEGTRVSIRLPLPPSGTAHGIIA
>Mature_513_residues
MNALRLKLWMTLAFVMLTVAVPGVIARHALGVVRAQHARSEASSQSLSAFQRLAVLGYTLQQERYVDPEGFAKDRLLYID
GVRSHVTNAERYINAEIRLISETPLDRRNRAKSIEEEVKQRAKLHVIGANLEKSLMGDGRETLWEDLVFEAIKVEEREAK
EYQRSSIETFQSVSDTLFLTVSVVGIFGILALIWGQRQVIRPLGALWRGTREMAEGRYDRRVPVVGTTEFRTIANSFNTM
AARVEEAALSMQRTNEELERAVARRTSELATTNRSLERANRLRRQFLADASHELRTPLSIMRSEAEITLRKADADMDELR
TGLDRVVRLSALMAEMIEDMLQVARAEEPMLQTVIAPFDVVAATRTCIDDFHRVIEDDGGQIILTECPDALIVEGDAVRL
QQVIRIVVDNAVCYSSHAPHVEVAIRQEEGDAVIEVSDQGDGIPAEDIPHLFQRFRRGSRKVGSGQGLGLSIARSILEAL
GGTISLESRLHEGTRVSIRLPLPPSGTAHGIIA

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=356, Percent_Identity=28.0898876404494, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788393, Length=315, Percent_Identity=26.984126984127, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=29.6610169491525, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=336, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790551, Length=329, Percent_Identity=28.2674772036474, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786600, Length=384, Percent_Identity=26.8229166666667, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=343, Percent_Identity=25.9475218658892, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790861, Length=217, Percent_Identity=25.3456221198157, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=26.2172284644195, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=308, Percent_Identity=25.974025974026, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=24.5454545454545, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=24.6913580246914, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57230; Mature: 57230

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALRLKLWMTLAFVMLTVAVPGVIARHALGVVRAQHARSEASSQSLSAFQRLAVLGYTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQERYVDPEGFAKDRLLYIDGVRSHVTNAERYINAEIRLISETPLDRRNRAKSIEEEVKQ
HHCCCCCCCCCCCCCEEEEECHHHHHCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
RAKLHVIGANLEKSLMGDGRETLWEDLVFEAIKVEEREAKEYQRSSIETFQSVSDTLFLT
HHEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVVGIFGILALIWGQRQVIRPLGALWRGTREMAEGRYDRRVPVVGTTEFRTIANSFNTM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHH
AARVEEAALSMQRTNEELERAVARRTSELATTNRSLERANRLRRQFLADASHELRTPLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHH
MRSEAEITLRKADADMDELRTGLDRVVRLSALMAEMIEDMLQVARAEEPMLQTVIAPFDV
HHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAATRTCIDDFHRVIEDDGGQIILTECPDALIVEGDAVRLQQVIRIVVDNAVCYSSHAPH
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCEECCCCCC
VEVAIRQEEGDAVIEVSDQGDGIPAEDIPHLFQRFRRGSRKVGSGQGLGLSIARSILEAL
EEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
GGTISLESRLHEGTRVSIRLPLPPSGTAHGIIA
CCCEEEHHHHCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNALRLKLWMTLAFVMLTVAVPGVIARHALGVVRAQHARSEASSQSLSAFQRLAVLGYTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQERYVDPEGFAKDRLLYIDGVRSHVTNAERYINAEIRLISETPLDRRNRAKSIEEEVKQ
HHCCCCCCCCCCCCCEEEEECHHHHHCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
RAKLHVIGANLEKSLMGDGRETLWEDLVFEAIKVEEREAKEYQRSSIETFQSVSDTLFLT
HHEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVVGIFGILALIWGQRQVIRPLGALWRGTREMAEGRYDRRVPVVGTTEFRTIANSFNTM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHH
AARVEEAALSMQRTNEELERAVARRTSELATTNRSLERANRLRRQFLADASHELRTPLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHH
MRSEAEITLRKADADMDELRTGLDRVVRLSALMAEMIEDMLQVARAEEPMLQTVIAPFDV
HHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VAATRTCIDDFHRVIEDDGGQIILTECPDALIVEGDAVRLQQVIRIVVDNAVCYSSHAPH
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCEECCCCCC
VEVAIRQEEGDAVIEVSDQGDGIPAEDIPHLFQRFRRGSRKVGSGQGLGLSIARSILEAL
EEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
GGTISLESRLHEGTRVSIRLPLPPSGTAHGIIA
CCCEEEHHHHCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]