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The map label for this gene is argS

Identifier: 87199111

GI number: 87199111

Start: 1131811

End: 1133559

Strand: Direct

Name: argS

Synonym: Saro_1089

Alternate gene names: 87199111

Gene position: 1131811-1133559 (Clockwise)

Preceding gene: 87199110

Following gene: 87199112

Centisome position: 31.78

GC content: 64.78

Gene sequence:

>1749_bases
ATGACTGACGCCACGATCAATCTTCACGCCGACTTCGCTCGGGTCATCGACGCTGCGCTTGATGCGCTGGAAGCTGCGGG
CACGCTGCCTGGCACCCTGTCGCGAAGCGCCGTCACCTGCGAACCGCCCCGCGATCCGAGCCATGGCGATCTGGCGACCA
ACGCGGCCATGGTCCTGGCCAAGCCCGCGGGCACCAATCCGCGCGCATTGGCGACGGCGCTGGCGGCAGAGCTTGAAAAG
GAGCCGCGCGTCGTTTCCGCCGAGATCGCCGGTCCGGGGTTCATCAACCTGCGCCTGACCGACGACGCCTGGCGCGGCGA
GCTTGCGCTGATCGGCTCGGCGGGCGCGGACTACGGGCGTTCGACGATGGGCGGCAGCAAGGTCGTGAACGTCGAATACG
TCTCGGCCAATCCCACGGGGCCGATGCACATGGGCCATTGCCGGGGCGCGGTGGTGGGCGATGCCCTGGCCGATCTGCTG
GCCTTCAGCGGACACCAGGTCATCAAGGAATACTACGTCAACGATGCTGGTGCGCAGGTCGACGTGCTCGCCCGCTCGGT
CCACATGCGCTACCGCGAGGCGCTGGGCGAAACGGTCGAGATTCCCGAAGGTCTTTATCCTGGCGACTATCTCGTTCCTG
TGGGCAAGGCGCTCGCCGAGGAATTTGGCGACAAGTATGCCAAGGCGGCCGAAGCCGACTGGCTGATCCTGTTCCGCACG
CGCGCCGTTGCGGCGATGATGGACATGATCCGCTCCGACCTTGCGACGCTGGGGATCCACCACGACCTTTTCTCCTCCGA
AGCGGAGCTTCAGGCATCGGGCAAGGTGGACGCCGCCGAGCAGTGGCTGCGGGCACATGACCTGGTATACGATGGCCTGC
TCGAAGCGCCCAAGGGCAAGACCCCCGAGGACTGGGAGCCGGTGGTGCTGCCGTTGTTCCGCTCCACGAAGTTCGGTGAC
GATCAGGACCGCCCGATCAAGAAGTCGAACGGAGCGTGGACCTATTTCGGCGCGGACCTCGCCTACCACTTTCAGAAGGC
GCAGACTGCCGATGCCCTCGTCGACATCTGGGGCGCGGACCACGCTGGCACTGTCAAGCGGATCAAGGCCGCAGTTGCGG
CGTTGACCAGCGCGGACGGCGGCACGCCCAAGCCCTTCGAGGTCAAGCTGGTACAGATGGTCCAGTTGCTGCGCGACGGC
GAGCCGGTGAAAATGTCCAAGCGTTCCGGCAACTTCGTTACGCTTTCTGACGTGGTCGAAGAAGTCGGCAAGGATGTGGT
GCGCTTCACCATGCTCACCCGCAAGCCCGACGCGCAGATGGATTTCGACTTCGCCAAGGTGGTCGAGGCGTCGAAGGACA
ACCCGGTGTTCTACGTGCAGTATGCCCATGCCCGCATCTGCCGGAACCTGCGCAAGGGCGCTGACGAGGGCTTTGCGCCT
TCATCCGCCAATCTCGACCTGCTGGGTGATGAGGAACTGGCGCTGGTCAAGCTTGCCGCGCAGTTCCCGCGCACGATCGA
GGCCGCCGCGGCGGCGCGCGAACCGCACCGGATCGCATTCTTCCTGCACGACCTCGCGTCGGCCTTCCACTCGTTCTACA
ATCTGGGGAACGACCGTCCGGACAAACGCTTCATTGTGGCACAAGACTCCGCAATGACCGCAGCCCGCCTTTTCCTTGCC
GCGCAAATCGGGCAGGTAATCCGCAATGGCCTCGCTGTCCTTGGCGTCGAGGCCGCGCAAGAGCTTTGA

Upstream 100 bases:

>100_bases
GCCGCTGACGGACCGTTTATCCGGGCCGATTGCGGGAACAGGAAAGGGCGTCTGATCGGCGCCCTTTCGCTTTTGGCGCG
ATTGGGCTAACCGCCCGCCC

Downstream 100 bases:

>100_bases
TGGGCAAAACGGGGCGGGCTACGGCATGAACGGCGAAGGCGGTCAGAATTCCTGGGATGAGCAGGCGGCGGGCAAGCCGT
TTGACGTATCGGCGGAACTC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MTDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLAKPAGTNPRALATALAAELEK
EPRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGRSTMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLL
AFSGHQVIKEYYVNDAGAQVDVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRT
RAVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGKTPEDWEPVVLPLFRSTKFGD
DQDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGADHAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDG
EPVKMSKRSGNFVTLSDVVEEVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAP
SSANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRPDKRFIVAQDSAMTAARLFLA
AQIGQVIRNGLAVLGVEAAQEL

Sequences:

>Translated_582_residues
MTDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLAKPAGTNPRALATALAAELEK
EPRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGRSTMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLL
AFSGHQVIKEYYVNDAGAQVDVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRT
RAVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGKTPEDWEPVVLPLFRSTKFGD
DQDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGADHAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDG
EPVKMSKRSGNFVTLSDVVEEVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAP
SSANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRPDKRFIVAQDSAMTAARLFLA
AQIGQVIRNGLAVLGVEAAQEL
>Mature_581_residues
TDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLAKPAGTNPRALATALAAELEKE
PRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGRSTMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLLA
FSGHQVIKEYYVNDAGAQVDVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRTR
AVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGKTPEDWEPVVLPLFRSTKFGDD
QDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGADHAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDGE
PVKMSKRSGNFVTLSDVVEEVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAPS
SANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRPDKRFIVAQDSAMTAARLFLAA
QIGQVIRNGLAVLGVEAAQEL

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=594, Percent_Identity=23.7373737373737, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1788184, Length=597, Percent_Identity=25.7956448911223, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71985061, Length=625, Percent_Identity=22.4, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985068, Length=573, Percent_Identity=22.8621291448517, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=25.3496503496504, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI18859963, Length=590, Percent_Identity=23.5593220338983, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_NOVAD (Q2G9D9)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496368.1
- ProteinModelPortal:   Q2G9D9
- STRING:   Q2G9D9
- GeneID:   3916385
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_1089
- NMPDR:   fig|48935.1.peg.1276
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   ETIRGCL
- ProtClustDB:   PRK01611
- BioCyc:   NARO279238:SARO_1089-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62755; Mature: 62624

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00178 AA_TRNA_LIGASE_I; PS00014 ER_TARGET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLA
CCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHCCCEEEEE
KPAGTNPRALATALAAELEKEPRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGR
ECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCC
STMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLLAFSGHQVIKEYYVNDAGAQV
CCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
DVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRT
HHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
RAVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TPEDWEPVVLPLFRSTKFGDDQDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGAD
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCC
HAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDGEPVKMSKRSGNFVTLSDVVE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHH
EVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAP
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCC
SSANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRP
CCCCEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
DKRFIVAQDSAMTAARLFLAAQIGQVIRNGLAVLGVEAAQEL
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHCC
>Mature Secondary Structure 
TDATINLHADFARVIDAALDALEAAGTLPGTLSRSAVTCEPPRDPSHGDLATNAAMVLA
CCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHCCCEEEEE
KPAGTNPRALATALAAELEKEPRVVSAEIAGPGFINLRLTDDAWRGELALIGSAGADYGR
ECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCC
STMGGSKVVNVEYVSANPTGPMHMGHCRGAVVGDALADLLAFSGHQVIKEYYVNDAGAQV
CCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHH
DVLARSVHMRYREALGETVEIPEGLYPGDYLVPVGKALAEEFGDKYAKAAEADWLILFRT
HHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
RAVAAMMDMIRSDLATLGIHHDLFSSEAELQASGKVDAAEQWLRAHDLVYDGLLEAPKGK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
TPEDWEPVVLPLFRSTKFGDDQDRPIKKSNGAWTYFGADLAYHFQKAQTADALVDIWGAD
CCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCC
HAGTVKRIKAAVAALTSADGGTPKPFEVKLVQMVQLLRDGEPVKMSKRSGNFVTLSDVVE
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHH
EVGKDVVRFTMLTRKPDAQMDFDFAKVVEASKDNPVFYVQYAHARICRNLRKGADEGFAP
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCC
SSANLDLLGDEELALVKLAAQFPRTIEAAAAAREPHRIAFFLHDLASAFHSFYNLGNDRP
CCCCEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
DKRFIVAQDSAMTAARLFLAAQIGQVIRNGLAVLGVEAAQEL
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA