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The map label for this gene is engA

Identifier: 87198885

GI number: 87198885

Start: 913308

End: 914693

Strand: Direct

Name: engA

Synonym: Saro_0863

Alternate gene names: 87198885

Gene position: 913308-914693 (Clockwise)

Preceding gene: 87198883

Following gene: 87198888

Centisome position: 25.64

GC content: 64.86

Gene sequence:

>1386_bases
ATGCGCCCTCAGGTAATCATCATCGGACGCCCCAATGTGGGCAAGTCCACGCTGTTCAACCGACTCGTCGGCAAGAAGCT
GGCGCTGGTCGACGACCAGCCGGGCGTGACCCGCGACCGCCGTTTTGGCGATGCTTCTCTACTGGGTCTCGACTTCACCA
TCGTCGATACCGCCGGTTGGGAGGACGAGGACCCCTCGACGCTGCCCGGCCGCATGCGCAAGCAGACAGAGGCTTCGCTC
GTCGGCGCGGATGTCGCCTTGTTCGTCATCGATGCGCGCGCGGGCGTCACGCCGCTGGACGAGGAAATCGCCCGTTACCT
GCGCCAGAGCACGGTGCCGATCGTACTCATGGCCAACAAGGCCGAAGGCCGCGCCGGCGATCCCGGGATTTTCGAGGCAT
TCTCGCTCGGCTTCGGTGAACCCGTCGCCTTTTCCGCCGAACATGGTCAGGGCCTTGCCGACCTTTTCGAGGCGCTGCTG
CCGCTGATCGGCGAAAAGCAGGACGACGAGGACGGCGAAGGTGAAGAGGCCGAGGACGAGGAAGAGGAGTTCGATCCCGA
ATCCGTTCTCAAGCTGGCCATCGTGGGCCGTCCCAACGCCGGCAAGTCGACGCTGATCAACAAGCTGCTCGGCGAGGATC
GCCTGCTGACCGGGCCGGAAGCCGGGATCACCCGCGATTCCATCGCCATCGACTGGCAGTGGTTCGATCCGGAACGCGAA
GCCTATCGCCCGGTCCGCCTGATCGACACGGCCGGCATGCGCAAGAAGGCGCAGGTCACCGACAAGCTCGAAAAGCTTTC
TGTCGCCGACGCGCGCCATGCCATCGATTTCGCCGAAGTCGTGGTGCTGGTTCTCGATGCCACGCGCGGGCTTGAACATC
AGGATCTCAAGATCGCCTCGATGGTGATCGAAGAAGGCCGCGCACTGATGATCGCGATCAACAAGTGGGATGTCGCCGAA
GATCCTTCGGGCCTGTTCCAAGGTATCCGCAAGGCGCTCGACGAAGGGCTGGCGCAGGTGCGCGGCGTGCCATTGCTCGC
CATTTCGGGCCGCACCGGCAAGGGATTGGACGAACTGCTGAAAGCGGCCTTCGAAATCCGCGCCGCCTGGTCGAAGCGCG
TGCCGACCGCCGCTCTCAACCGCTGGTTCGACGACGCGCTCGCCGCCAATCCGCCGCCCGCGCCCGGCGGACGCCGGATC
AAGCTGCGCTACATCACCCAGGCCAAGACGCGTCCCCCCGGTTTCGTTCTGTTCGGCACGCGTCTGGACCAGTTGCCCGA
AAGCTACCGGCGCTATCTGATCAACGGCATCCGGCGCGAGCTGGGCTTCGATGCCGTGCCGATCCGCCTGACCCTGCGCA
GCCCCAAGAACCCGTTCGCCAAGTAG

Upstream 100 bases:

>100_bases
TTATGTTCATACTCCCGTGAATGGTTAATGGCGGCATAACGAATGCACCGGACTTAAAGCCGTGCTTGCGTTCACGCGCA
GGAACAGCCACGGAAAAACC

Downstream 100 bases:

>100_bases
TCAGAACGCTGCCTTGACCCCGACGCTCCACCGGCGCGGGGCGGCGGGCCCGAGGGCGCGCGGGTCCTGCGCGTCGGGCG
CTTCGGCAAGATAGACCTCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRPQVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRFGDASLLGLDFTIVDTAGWEDEDPSTLPGRMRKQTEASL
VGADVALFVIDARAGVTPLDEEIARYLRQSTVPIVLMANKAEGRAGDPGIFEAFSLGFGEPVAFSAEHGQGLADLFEALL
PLIGEKQDDEDGEGEEAEDEEEEFDPESVLKLAIVGRPNAGKSTLINKLLGEDRLLTGPEAGITRDSIAIDWQWFDPERE
AYRPVRLIDTAGMRKKAQVTDKLEKLSVADARHAIDFAEVVVLVLDATRGLEHQDLKIASMVIEEGRALMIAINKWDVAE
DPSGLFQGIRKALDEGLAQVRGVPLLAISGRTGKGLDELLKAAFEIRAAWSKRVPTAALNRWFDDALAANPPPAPGGRRI
KLRYITQAKTRPPGFVLFGTRLDQLPESYRRYLINGIRRELGFDAVPIRLTLRSPKNPFAK

Sequences:

>Translated_461_residues
MRPQVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRFGDASLLGLDFTIVDTAGWEDEDPSTLPGRMRKQTEASL
VGADVALFVIDARAGVTPLDEEIARYLRQSTVPIVLMANKAEGRAGDPGIFEAFSLGFGEPVAFSAEHGQGLADLFEALL
PLIGEKQDDEDGEGEEAEDEEEEFDPESVLKLAIVGRPNAGKSTLINKLLGEDRLLTGPEAGITRDSIAIDWQWFDPERE
AYRPVRLIDTAGMRKKAQVTDKLEKLSVADARHAIDFAEVVVLVLDATRGLEHQDLKIASMVIEEGRALMIAINKWDVAE
DPSGLFQGIRKALDEGLAQVRGVPLLAISGRTGKGLDELLKAAFEIRAAWSKRVPTAALNRWFDDALAANPPPAPGGRRI
KLRYITQAKTRPPGFVLFGTRLDQLPESYRRYLINGIRRELGFDAVPIRLTLRSPKNPFAK
>Mature_461_residues
MRPQVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRFGDASLLGLDFTIVDTAGWEDEDPSTLPGRMRKQTEASL
VGADVALFVIDARAGVTPLDEEIARYLRQSTVPIVLMANKAEGRAGDPGIFEAFSLGFGEPVAFSAEHGQGLADLFEALL
PLIGEKQDDEDGEGEEAEDEEEEFDPESVLKLAIVGRPNAGKSTLINKLLGEDRLLTGPEAGITRDSIAIDWQWFDPERE
AYRPVRLIDTAGMRKKAQVTDKLEKLSVADARHAIDFAEVVVLVLDATRGLEHQDLKIASMVIEEGRALMIAINKWDVAE
DPSGLFQGIRKALDEGLAQVRGVPLLAISGRTGKGLDELLKAAFEIRAAWSKRVPTAALNRWFDDALAANPPPAPGGRRI
KLRYITQAKTRPPGFVLFGTRLDQLPESYRRYLINGIRRELGFDAVPIRLTLRSPKNPFAK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=479, Percent_Identity=41.3361169102296, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=31.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367268, Length=177, Percent_Identity=30.5084745762712, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_NOVAD (Q2GA15)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_496142.1
- ProteinModelPortal:   Q2GA15
- SMR:   Q2GA15
- STRING:   Q2GA15
- GeneID:   3915919
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_0863
- NMPDR:   fig|48935.1.peg.3418
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q2GA15
- ProtClustDB:   PRK00093
- BioCyc:   NARO279238:SARO_0863-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50626; Mature: 50626

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPQVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRFGDASLLGLDFTIVDTAGW
CCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCC
EDEDPSTLPGRMRKQTEASLVGADVALFVIDARAGVTPLDEEIARYLRQSTVPIVLMANK
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
AEGRAGDPGIFEAFSLGFGEPVAFSAEHGQGLADLFEALLPLIGEKQDDEDGEGEEAEDE
CCCCCCCCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
EEEFDPESVLKLAIVGRPNAGKSTLINKLLGEDRLLTGPEAGITRDSIAIDWQWFDPERE
HHHCCHHHEEEEEEECCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCHHH
AYRPVRLIDTAGMRKKAQVTDKLEKLSVADARHAIDFAEVVVLVLDATRGLEHQDLKIAS
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MVIEEGRALMIAINKWDVAEDPSGLFQGIRKALDEGLAQVRGVPLLAISGRTGKGLDELL
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
KAAFEIRAAWSKRVPTAALNRWFDDALAANPPPAPGGRRIKLRYITQAKTRPPGFVLFGT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECC
RLDQLPESYRRYLINGIRRELGFDAVPIRLTLRSPKNPFAK
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MRPQVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRFGDASLLGLDFTIVDTAGW
CCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCC
EDEDPSTLPGRMRKQTEASLVGADVALFVIDARAGVTPLDEEIARYLRQSTVPIVLMANK
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
AEGRAGDPGIFEAFSLGFGEPVAFSAEHGQGLADLFEALLPLIGEKQDDEDGEGEEAEDE
CCCCCCCCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
EEEFDPESVLKLAIVGRPNAGKSTLINKLLGEDRLLTGPEAGITRDSIAIDWQWFDPERE
HHHCCHHHEEEEEEECCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEEECCHHH
AYRPVRLIDTAGMRKKAQVTDKLEKLSVADARHAIDFAEVVVLVLDATRGLEHQDLKIAS
HCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MVIEEGRALMIAINKWDVAEDPSGLFQGIRKALDEGLAQVRGVPLLAISGRTGKGLDELL
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
KAAFEIRAAWSKRVPTAALNRWFDDALAANPPPAPGGRRIKLRYITQAKTRPPGFVLFGT
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCEEEECC
RLDQLPESYRRYLINGIRRELGFDAVPIRLTLRSPKNPFAK
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA