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The map label for this gene is benK [H]

Identifier: 87198826

GI number: 87198826

Start: 854402

End: 855700

Strand: Direct

Name: benK [H]

Synonym: Saro_0804

Alternate gene names: 87198826

Gene position: 854402-855700 (Clockwise)

Preceding gene: 87198825

Following gene: 87198827

Centisome position: 23.99

GC content: 67.13

Gene sequence:

>1299_bases
ATGTCACAAACCCCGCGCGAGGTGATCGAGCAGACGCCGATGGGCGTCCGCCAGTGGATCGCCGTGGTCCTGATGATCGC
GCTGAACGCGCTCGACGGGTTCGACGTCCTGTCCAGCGCCTTTGCCGCCCCCGGCATCGCCAAGGAATGGGGCATCCAGC
GCGACGCGCTGGGTGTCGTGCTGTCGATGGAACTGGTCGGCATGGGCTTTGGCTCGATCCTGCTGGGCGGCGCGGCGGAC
CGCTTCGGGCGGCGTCCGACTATCCTCGGCTGCCTGTTGGTCATGGCCACCGGCATGTGGCTGGCGACGACTTCGGCGAG
CCCGTCGGGCCTTGCCCTGTGGCGCTTCATCACCGGCCTCGGCATCGGCGGCATGCTGGCGGCGATCAACGCGGTGACGG
CCGAATTCTCCAGCCTCAAGGGCCGTTCGCTGGCCATGGCGCTGATGGTCATCGGATACCCGATCGGCGCGACGGTGGGC
GGGACCATCGCCGGAATGCTGCTGAAGGGTGGCGACTGGCGGCTGGTCTTCGAATTCGGCGCGATCGCCACGGCGGTGTT
CATCCCGCTCGTGTTCCTGTTCGTGCCCGAGACGCCGGATTACTACGTCACCCGTCGCGAGCCGGACGCGCTCGACAAGG
TCAACGCCAGCCTGCGCAAGCTGGCCCTGCCGCTCGCCACGATCCTGCCGCCTGCGCCGGCAGTGGTCGACAAGCCGAGC
GTGTTCGACATCTTCAAGCCCGGCCTGATCCGGACGACCCTGCTGTTCACGCTAGGCTATTCGTTCCACGCGGTGACGTT
CTACTACATCCTCAAGTGGAGCCCCAAGATCGTCGCGGACTTCGGTTACACCCAGCCCGAGGCTGCGAGCGTGCTGGTCT
GGGCGAACATCGGCGGGGCGACCGGCGGGGCGCTGTTCGGATTTGCCATGCACAAGTTCGGGTTGAAGTGGCCGACCATC
GCGATGCTGGTTGGCGGCGCGATTGCGGTCGTGGCTTTCGGCTTCGGACGAGAGAGCCTCGACGGGTGGAAGATGGCGGT
GTTCTTCACCGGCTTCACCACCAACGCCGCGATCGTCGGCTTCTACGCCCTCTTCGCCAAGGGCTTCCCGACCCACGTGC
GGGCGACCGGCACCGGCTTTGCCATCGGCGCCGGACGCATCGGCGCAGCGGGTTCGCCGATCCTGGCGGGCGTGCTGTTC
ACGCAGGCAGGCCTCGGTCTGCTGGGCGTCTCGGTCGTGATGGCGATGGGATCGGTCGTGGCAGCGCTGCTGCTGCTGAT
GCTGCGCAAGGAAGTCTAG

Upstream 100 bases:

>100_bases
CCGACAAGGAAGTGCGGCAGCTCATCGAACTGCTTTCCAGAATCCACGAATAAGTTATAAGCAATAGCAATCAGAATTTT
GGGATGAGGAATCGGGTCGC

Downstream 100 bases:

>100_bases
GCCGTTCGCATATGTGAACGAGGTTTACACGGTTTATACAGTCCAGAGCGAAATCGAGGGGCCGGGGCGGACAGGGTTCG
CACCGGCCCTTTCGCGTTGA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSQTPREVIEQTPMGVRQWIAVVLMIALNALDGFDVLSSAFAAPGIAKEWGIQRDALGVVLSMELVGMGFGSILLGGAAD
RFGRRPTILGCLLVMATGMWLATTSASPSGLALWRFITGLGIGGMLAAINAVTAEFSSLKGRSLAMALMVIGYPIGATVG
GTIAGMLLKGGDWRLVFEFGAIATAVFIPLVFLFVPETPDYYVTRREPDALDKVNASLRKLALPLATILPPAPAVVDKPS
VFDIFKPGLIRTTLLFTLGYSFHAVTFYYILKWSPKIVADFGYTQPEAASVLVWANIGGATGGALFGFAMHKFGLKWPTI
AMLVGGAIAVVAFGFGRESLDGWKMAVFFTGFTTNAAIVGFYALFAKGFPTHVRATGTGFAIGAGRIGAAGSPILAGVLF
TQAGLGLLGVSVVMAMGSVVAALLLLMLRKEV

Sequences:

>Translated_432_residues
MSQTPREVIEQTPMGVRQWIAVVLMIALNALDGFDVLSSAFAAPGIAKEWGIQRDALGVVLSMELVGMGFGSILLGGAAD
RFGRRPTILGCLLVMATGMWLATTSASPSGLALWRFITGLGIGGMLAAINAVTAEFSSLKGRSLAMALMVIGYPIGATVG
GTIAGMLLKGGDWRLVFEFGAIATAVFIPLVFLFVPETPDYYVTRREPDALDKVNASLRKLALPLATILPPAPAVVDKPS
VFDIFKPGLIRTTLLFTLGYSFHAVTFYYILKWSPKIVADFGYTQPEAASVLVWANIGGATGGALFGFAMHKFGLKWPTI
AMLVGGAIAVVAFGFGRESLDGWKMAVFFTGFTTNAAIVGFYALFAKGFPTHVRATGTGFAIGAGRIGAAGSPILAGVLF
TQAGLGLLGVSVVMAMGSVVAALLLLMLRKEV
>Mature_431_residues
SQTPREVIEQTPMGVRQWIAVVLMIALNALDGFDVLSSAFAAPGIAKEWGIQRDALGVVLSMELVGMGFGSILLGGAADR
FGRRPTILGCLLVMATGMWLATTSASPSGLALWRFITGLGIGGMLAAINAVTAEFSSLKGRSLAMALMVIGYPIGATVGG
TIAGMLLKGGDWRLVFEFGAIATAVFIPLVFLFVPETPDYYVTRREPDALDKVNASLRKLALPLATILPPAPAVVDKPSV
FDIFKPGLIRTTLLFTLGYSFHAVTFYYILKWSPKIVADFGYTQPEAASVLVWANIGGATGGALFGFAMHKFGLKWPTIA
MLVGGAIAVVAFGFGRESLDGWKMAVFFTGFTTNAAIVGFYALFAKGFPTHVRATGTGFAIGAGRIGAAGSPILAGVLFT
QAGLGLLGVSVVMAMGSVVAALLLLMLRKEV

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=432, Percent_Identity=22.2222222222222, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI213021148, Length=430, Percent_Identity=25.3488372093023, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=420, Percent_Identity=27.3809523809524, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082404, Length=402, Percent_Identity=23.8805970149254, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082231, Length=467, Percent_Identity=20.1284796573876, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=409, Percent_Identity=24.2053789731051, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32565921, Length=388, Percent_Identity=24.2268041237113, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922616, Length=396, Percent_Identity=23.989898989899, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45329; Mature: 45198

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTPREVIEQTPMGVRQWIAVVLMIALNALDGFDVLSSAFAAPGIAKEWGIQRDALGVV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCHHHHHHH
LSMELVGMGFGSILLGGAADRFGRRPTILGCLLVMATGMWLATTSASPSGLALWRFITGL
HHHHHHHCCHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHC
GIGGMLAAINAVTAEFSSLKGRSLAMALMVIGYPIGATVGGTIAGMLLKGGDWRLVFEFG
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCEEEEEEHH
AIATAVFIPLVFLFVPETPDYYVTRREPDALDKVNASLRKLALPLATILPPAPAVVDKPS
HHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VFDIFKPGLIRTTLLFTLGYSFHAVTFYYILKWSPKIVADFGYTQPEAASVLVWANIGGA
HHHHHCCHHHHHHHHHHHCCHHHHEEEEHHEECCCCEEEECCCCCCCCCEEEEEEECCCC
TGGALFGFAMHKFGLKWPTIAMLVGGAIAVVAFGFGRESLDGWKMAVFFTGFTTNAAIVG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHH
FYALFAKGFPTHVRATGTGFAIGAGRIGAAGSPILAGVLFTQAGLGLLGVSVVMAMGSVV
HHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AALLLLMLRKEV
HHHHHHHHHHCC
>Mature Secondary Structure 
SQTPREVIEQTPMGVRQWIAVVLMIALNALDGFDVLSSAFAAPGIAKEWGIQRDALGVV
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCHHHHHHH
LSMELVGMGFGSILLGGAADRFGRRPTILGCLLVMATGMWLATTSASPSGLALWRFITGL
HHHHHHHCCHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHC
GIGGMLAAINAVTAEFSSLKGRSLAMALMVIGYPIGATVGGTIAGMLLKGGDWRLVFEFG
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCEEEEEEHH
AIATAVFIPLVFLFVPETPDYYVTRREPDALDKVNASLRKLALPLATILPPAPAVVDKPS
HHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VFDIFKPGLIRTTLLFTLGYSFHAVTFYYILKWSPKIVADFGYTQPEAASVLVWANIGGA
HHHHHCCHHHHHHHHHHHCCHHHHEEEEHHEECCCCEEEECCCCCCCCCEEEEEEECCCC
TGGALFGFAMHKFGLKWPTIAMLVGGAIAVVAFGFGRESLDGWKMAVFFTGFTTNAAIVG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHH
FYALFAKGFPTHVRATGTGFAIGAGRIGAAGSPILAGVLFTQAGLGLLGVSVVMAMGSVV
HHHHHHCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AALLLLMLRKEV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]