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The map label for this gene is mhpC [C]

Identifier: 87198715

GI number: 87198715

Start: 730917

End: 731789

Strand: Direct

Name: mhpC [C]

Synonym: Saro_0691

Alternate gene names: 87198715

Gene position: 730917-731789 (Clockwise)

Preceding gene: 87198714

Following gene: 87198716

Centisome position: 20.52

GC content: 64.26

Gene sequence:

>873_bases
ATGCAGTTACTCGGTCCGACCTCGAACACCTTCATCTCCCAGCGCTTGCGCCTCCACTACGTGGACTGGGGCAATGCCGA
CAAGCCGCCGCTCCTGCTGGTGCATGGCGGGCGCGACCATTGCCGTTCGTGGGACTGGACGGCAGAGGCGCTGCGCGAGG
ACTGGCACATCATCGCGCTCGACCATCGCGGTCATGGCGATAGCCAGTGGACCCAGGACGGCAACTACCGCACGATGGAC
CTCGTCTATGACGTGGCCCAGCTTATCCACCAGCTAGACCTGGCACCGGTGACGATCGTCTCGCACTCGTGGGGCGCCAA
CACCAGCCTGCGCTATGCCGGCCTGTTCCCCGAGAACGTGCGCAAGATCGTGGCGATCGAGGGCCTGTTCCCCACGCCCG
AGCGCGAGGCTCTGATGAAGGACGTGCCCTTCGCTCGCCGCGTGCGCGAATTCATCGTCGAGAAGCGCAAGGCCGCCGGT
CGCCTGCCCCGCCGCTACGCGACGCTGGAAGACGCTTACGCGCGCATGAAGGGTGAAAACCCCTACCTGACCGACGCCCA
GGCCCGGCACCTGACGCTCCATGGCATCAACCGCAACGAGGACGGCACCTTCAGTTGGAAGTTCGACCCGCATCTCAATG
TCGATGGCGCGCCCTATGACATCAGCACCGACCAGCGCAACGAACTGTGGGGCGCGATCACCTGCCCGACGCTGCTGCTG
AACGGCGCGGATTCGTGGGCCGGAAATCCGGACAGGAACGGCATGGCGCAACATTTCCGCAATGCCCAAGTGGTCGAATT
CGAGAATGCCGGCCACTGGCTCCACCATGACCAGTTCGACCGGTTCATCGCCACGCTCAGGGATTTCCTCTGA

Upstream 100 bases:

>100_bases
CAACCCCGAACTCACCTTCTCTGCGACCAAGGAAAGGTAGTTCCGCCTTAGTCGGCCCGGGGGGTTGAAACCGCAGGGCG
AAGGGCGCAGTTAGCCTCCC

Downstream 100 bases:

>100_bases
GTGTCGGCGTGAAACTGAAGGTCGCCAGCTACAACATCCACAAGGGCGTCGGGCTTGACCGCCGCCGCGATCCGGACCGC
ATCCTGACTGTCCTGCGCGA

Product: alpha/beta hydrolase

Products: NA

Alternate protein names: Atropine acylhydrolase; Atropinesterase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MQLLGPTSNTFISQRLRLHYVDWGNADKPPLLLVHGGRDHCRSWDWTAEALREDWHIIALDHRGHGDSQWTQDGNYRTMD
LVYDVAQLIHQLDLAPVTIVSHSWGANTSLRYAGLFPENVRKIVAIEGLFPTPEREALMKDVPFARRVREFIVEKRKAAG
RLPRRYATLEDAYARMKGENPYLTDAQARHLTLHGINRNEDGTFSWKFDPHLNVDGAPYDISTDQRNELWGAITCPTLLL
NGADSWAGNPDRNGMAQHFRNAQVVEFENAGHWLHHDQFDRFIATLRDFL

Sequences:

>Translated_290_residues
MQLLGPTSNTFISQRLRLHYVDWGNADKPPLLLVHGGRDHCRSWDWTAEALREDWHIIALDHRGHGDSQWTQDGNYRTMD
LVYDVAQLIHQLDLAPVTIVSHSWGANTSLRYAGLFPENVRKIVAIEGLFPTPEREALMKDVPFARRVREFIVEKRKAAG
RLPRRYATLEDAYARMKGENPYLTDAQARHLTLHGINRNEDGTFSWKFDPHLNVDGAPYDISTDQRNELWGAITCPTLLL
NGADSWAGNPDRNGMAQHFRNAQVVEFENAGHWLHHDQFDRFIATLRDFL
>Mature_290_residues
MQLLGPTSNTFISQRLRLHYVDWGNADKPPLLLVHGGRDHCRSWDWTAEALREDWHIIALDHRGHGDSQWTQDGNYRTMD
LVYDVAQLIHQLDLAPVTIVSHSWGANTSLRYAGLFPENVRKIVAIEGLFPTPEREALMKDVPFARRVREFIVEKRKAAG
RLPRRYATLEDAYARMKGENPYLTDAQARHLTLHGINRNEDGTFSWKFDPHLNVDGAPYDISTDQRNELWGAITCPTLLL
NGADSWAGNPDRNGMAQHFRNAQVVEFENAGHWLHHDQFDRFIATLRDFL

Specific function: Alkaloid degradation [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI23200008, Length=271, Percent_Identity=27.6752767527675, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI23200012, Length=271, Percent_Identity=27.6752767527675, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI218777840, Length=117, Percent_Identity=31.6239316239316, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI13376164, Length=117, Percent_Identity=31.6239316239316, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI218777837, Length=119, Percent_Identity=31.0924369747899, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=296, Percent_Identity=23.3108108108108, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562298, Length=112, Percent_Identity=33.9285714285714, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.10 [H]

Molecular weight: Translated: 33342; Mature: 33342

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLGPTSNTFISQRLRLHYVDWGNADKPPLLLVHGGRDHCRSWDWTAEALREDWHIIAL
CCCCCCCCHHHHHHCEEEEEEECCCCCCCCEEEEECCHHHHCCCCHHHHHHHCCCEEEEE
DHRGHGDSQWTQDGNYRTMDLVYDVAQLIHQLDLAPVTIVSHSWGANTSLRYAGLFPENV
ECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCHHHC
RKIVAIEGLFPTPEREALMKDVPFARRVREFIVEKRKAAGRLPRRYATLEDAYARMKGEN
EEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
PYLTDAQARHLTLHGINRNEDGTFSWKFDPHLNVDGAPYDISTDQRNELWGAITCPTLLL
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHEEEEECHHHEE
NGADSWAGNPDRNGMAQHFRNAQVVEFENAGHWLHHDQFDRFIATLRDFL
CCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQLLGPTSNTFISQRLRLHYVDWGNADKPPLLLVHGGRDHCRSWDWTAEALREDWHIIAL
CCCCCCCCHHHHHHCEEEEEEECCCCCCCCEEEEECCHHHHCCCCHHHHHHHCCCEEEEE
DHRGHGDSQWTQDGNYRTMDLVYDVAQLIHQLDLAPVTIVSHSWGANTSLRYAGLFPENV
ECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCHHHC
RKIVAIEGLFPTPEREALMKDVPFARRVREFIVEKRKAAGRLPRRYATLEDAYARMKGEN
EEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
PYLTDAQARHLTLHGINRNEDGTFSWKFDPHLNVDGAPYDISTDQRNELWGAITCPTLLL
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHEEEEECHHHEE
NGADSWAGNPDRNGMAQHFRNAQVVEFENAGHWLHHDQFDRFIATLRDFL
CCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA