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The map label for this gene is trpS [H]

Identifier: 87198612

GI number: 87198612

Start: 633608

End: 634627

Strand: Direct

Name: trpS [H]

Synonym: Saro_0588

Alternate gene names: 87198612

Gene position: 633608-634627 (Clockwise)

Preceding gene: 87198611

Following gene: 87198613

Centisome position: 17.79

GC content: 65.78

Gene sequence:

>1020_bases
ATGCGTATCGTTTCCGGTATCCAGCCCACGGGCAATCTCCACCTCGGCAACTACCTGGGTGCGATCCGGAACTGGGTGCG
CATGCAGGACGAGTGGTCGGCCAAGGGCGGAGAATGCCTCTATTTCCTGGCGGACCTCCATGCCATCTCCATGCCGCACA
GCCCCGCCGAACTCGCCGCCAACACGCGTGAGATGGTGGCGGCGCTGGTTTCCTGCGGAATCGATCCCGACAAGTCCGTC
CTGTTCAACCAGGCGCAGGTCCCGGCCCATGCGGAAATGCAGTGGCTGCTGAACGGCACGGCCCGCATGGGCTGGCTGAA
CCGCATGACGCAGTGGAAGGACAAGGCTGGCAAGAACCGCGAGGGCGCCTCGGTCGCGCTGTTCACCTATCCGGTGCTCC
AGGCCGCCGACGTGCTGCTTTACCAGGCGACGCACGTTCCGGTGGGCGAAGACCAGAAGCAGCACCTCGAACTGGCCCGC
GACGTGGCGCAGAAGTTCAACAACGACTTCGCGTCGGAAGATGCGCCGGTGTTCACGCTGCCCGATCCGATCATCCCGCC
CGAGGCCGCGCGAATCATGTCGCTGCGCGACGGTTCGGCCAAGATGAGCAAGTCCGACCCTTCGGACATGAGCCGCATCA
ACCTGACCGACGATGCCGATGCGATCATGCAGAAGGTCAGGAAGGCCAAGACCGATCCCGAGCCGCTGCCGGGCACGATG
GAAGGGCTTGCGGGGCGTCCGGAAGCGAACAACCTCGTCGGCATCTACGCAGCCATGGCGGGCATTTCGCCCGCCGATGT
GCTCGCCCGGTTCGAGGGCCAGGGCTTCGGCCAGTTCAAGCCGGCGCTTGGCGAACTTCTGGTCGAGAAGCTTTCGCCGA
TGGCCGCGCGCTATCGCGAACTGCGCGAGGACCGGGCCGCGCTCGACGCGATCCTTGCCAAGGGTGCGGAAAAGGCGCGC
GCCCTGGCCGCCCCCACGCTGGCGCGGACCTATGACGCGCTGGGTCTCGTAAGAGGCTGA

Upstream 100 bases:

>100_bases
TGGTCGTCTATGGGCTAGCCGCCGTCCTGACCGGGGCTTTCCGGGCAGGCGACCTCAAGCTTCTCCTGCGGCGCGGCCGC
ACCAACTGAAGGCAAGCAGA

Downstream 100 bases:

>100_bases
TTTCAGTCCGGAATGGCTGGAAAATATGGCTGCCTGCAACTTATGTTGCAGGCACCATTCAACGTGCATTCAGCACCTCC
CGTCCATAAGTACGGCATGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MRIVSGIQPTGNLHLGNYLGAIRNWVRMQDEWSAKGGECLYFLADLHAISMPHSPAELAANTREMVAALVSCGIDPDKSV
LFNQAQVPAHAEMQWLLNGTARMGWLNRMTQWKDKAGKNREGASVALFTYPVLQAADVLLYQATHVPVGEDQKQHLELAR
DVAQKFNNDFASEDAPVFTLPDPIIPPEAARIMSLRDGSAKMSKSDPSDMSRINLTDDADAIMQKVRKAKTDPEPLPGTM
EGLAGRPEANNLVGIYAAMAGISPADVLARFEGQGFGQFKPALGELLVEKLSPMAARYRELREDRAALDAILAKGAEKAR
ALAAPTLARTYDALGLVRG

Sequences:

>Translated_339_residues
MRIVSGIQPTGNLHLGNYLGAIRNWVRMQDEWSAKGGECLYFLADLHAISMPHSPAELAANTREMVAALVSCGIDPDKSV
LFNQAQVPAHAEMQWLLNGTARMGWLNRMTQWKDKAGKNREGASVALFTYPVLQAADVLLYQATHVPVGEDQKQHLELAR
DVAQKFNNDFASEDAPVFTLPDPIIPPEAARIMSLRDGSAKMSKSDPSDMSRINLTDDADAIMQKVRKAKTDPEPLPGTM
EGLAGRPEANNLVGIYAAMAGISPADVLARFEGQGFGQFKPALGELLVEKLSPMAARYRELREDRAALDAILAKGAEKAR
ALAAPTLARTYDALGLVRG
>Mature_339_residues
MRIVSGIQPTGNLHLGNYLGAIRNWVRMQDEWSAKGGECLYFLADLHAISMPHSPAELAANTREMVAALVSCGIDPDKSV
LFNQAQVPAHAEMQWLLNGTARMGWLNRMTQWKDKAGKNREGASVALFTYPVLQAADVLLYQATHVPVGEDQKQHLELAR
DVAQKFNNDFASEDAPVFTLPDPIIPPEAARIMSLRDGSAKMSKSDPSDMSRINLTDDADAIMQKVRKAKTDPEPLPGTM
EGLAGRPEANNLVGIYAAMAGISPADVLARFEGQGFGQFKPALGELLVEKLSPMAARYRELREDRAALDAILAKGAEKAR
ALAAPTLARTYDALGLVRG

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=336, Percent_Identity=42.5595238095238, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI41352700, Length=184, Percent_Identity=50.5434782608696, Blast_Score=205, Evalue=4e-53,
Organism=Escherichia coli, GI1789786, Length=335, Percent_Identity=41.4925373134328, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=36.1194029850746, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=36.1194029850746, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320474, Length=356, Percent_Identity=38.4831460674157, Blast_Score=229, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=40.7079646017699, Blast_Score=235, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36831; Mature: 36831

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVSGIQPTGNLHLGNYLGAIRNWVRMQDEWSAKGGECLYFLADLHAISMPHSPAELAA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCHHHHHH
NTREMVAALVSCGIDPDKSVLFNQAQVPAHAEMQWLLNGTARMGWLNRMTQWKDKAGKNR
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
EGASVALFTYPVLQAADVLLYQATHVPVGEDQKQHLELARDVAQKFNNDFASEDAPVFTL
CCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
PDPIIPPEAARIMSLRDGSAKMSKSDPSDMSRINLTDDADAIMQKVRKAKTDPEPLPGTM
CCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCCCCCHH
EGLAGRPEANNLVGIYAAMAGISPADVLARFEGQGFGQFKPALGELLVEKLSPMAARYRE
HHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LREDRAALDAILAKGAEKARALAAPTLARTYDALGLVRG
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIVSGIQPTGNLHLGNYLGAIRNWVRMQDEWSAKGGECLYFLADLHAISMPHSPAELAA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCHHHHHH
NTREMVAALVSCGIDPDKSVLFNQAQVPAHAEMQWLLNGTARMGWLNRMTQWKDKAGKNR
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
EGASVALFTYPVLQAADVLLYQATHVPVGEDQKQHLELARDVAQKFNNDFASEDAPVFTL
CCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
PDPIIPPEAARIMSLRDGSAKMSKSDPSDMSRINLTDDADAIMQKVRKAKTDPEPLPGTM
CCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHEECCCCCHHHHHHHHHHHCCCCCCCCCHH
EGLAGRPEANNLVGIYAAMAGISPADVLARFEGQGFGQFKPALGELLVEKLSPMAARYRE
HHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LREDRAALDAILAKGAEKARALAAPTLARTYDALGLVRG
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]