| Definition | Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome. |
|---|---|
| Accession | NC_007794 |
| Length | 3,561,584 |
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The map label for this gene is benD
Identifier: 87198564
GI number: 87198564
Start: 589371
End: 590162
Strand: Direct
Name: benD
Synonym: Saro_0540
Alternate gene names: 87198564
Gene position: 589371-590162 (Clockwise)
Preceding gene: 87198563
Following gene: 87198565
Centisome position: 16.55
GC content: 67.3
Gene sequence:
>792_bases ATGTCTGAGTACGGGGCGCATTTCGCGGGTCGTTTTGACGGCAAGGTCATGGTCGTGACCGGGGCGGCGCAGGGGATCGG GCGCGGCGTGGCGGAGCGCGCGGCTGCCGAGGGCGCACAGGTCCTGCTGGTTGATCGTGCCGACTTCGTGACAGATGTTG CGGCAGCGATCGGGCCGAAGGCGCATGCGTTCGTGGCAGACCTCGAGGGGCATGCGGGCGCTGCGGCCGCCGTGGCGCAC GGGCTTGCGGTTTTCGGTCGGATCGACATCCTGATCAACAACGTCGGCGGCGCGATCCGCATGCGGCCTTACGATCAGTT CACGTCCGAGCAGATCGATGCCGAAATCCGCCGCTCGCTGATGCCGACGCTCTACTGCTGCCATGCGGTGCTGCCGCCGA TGCTGGCGCAAGGGGCGGGGACGATCGTCAACGTATCGTCCAATGCCACGCGTGGGATACGGCGCGGGCCGTACTCGGCG GCGAAGGGCGGGATCAACGCTCTGACCCAGAGCCTCGCCATGGAGTATGGCGAGCAAGGCATCCGCGTCGTCGCCACGGC GCCGGGCGGCACGAGTGCGCCCGCACGCAAGGTTCCGCGCAATGCCGAGGGCGACAGCGCGCAGGAGCAGGCTTGGATGG CAGAGGCGGTGGAGCAGGTGACCCGGTCCACCTTCATGAAACGCTATGGCACGCTCGAGGAGCAGATCGCACCGATCCTG TTCCTCGCGTCCGACGAGGCAAGTTACATTACGGGAACCGTCCTGCCCGTTGCGGGCGGTGATCTCGGCTGA
Upstream 100 bases:
>100_bases ACCTTCTGCACGCTGCGACGGAGCATGGACGGCTTCAGCATTGGCTCCAAGAAGGTCGTGCTGAAGAACGACTACATCCA CCAGGTGATCGATGTCTATC
Downstream 100 bases:
>100_bases GCAGTCCAGAAGGCTATCGAGAAGGCATCTAACATAGACAGCCCTTATGCCTGCGATTACGCTCGCGTGATGAGTGACGC CCCGCAGCACCGCCTGAAGA
Product: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
Products: NA
Alternate protein names: 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase [H]
Number of amino acids: Translated: 263; Mature: 262
Protein sequence:
>263_residues MSEYGAHFAGRFDGKVMVVTGAAQGIGRGVAERAAAEGAQVLLVDRADFVTDVAAAIGPKAHAFVADLEGHAGAAAAVAH GLAVFGRIDILINNVGGAIRMRPYDQFTSEQIDAEIRRSLMPTLYCCHAVLPPMLAQGAGTIVNVSSNATRGIRRGPYSA AKGGINALTQSLAMEYGEQGIRVVATAPGGTSAPARKVPRNAEGDSAQEQAWMAEAVEQVTRSTFMKRYGTLEEQIAPIL FLASDEASYITGTVLPVAGGDLG
Sequences:
>Translated_263_residues MSEYGAHFAGRFDGKVMVVTGAAQGIGRGVAERAAAEGAQVLLVDRADFVTDVAAAIGPKAHAFVADLEGHAGAAAAVAH GLAVFGRIDILINNVGGAIRMRPYDQFTSEQIDAEIRRSLMPTLYCCHAVLPPMLAQGAGTIVNVSSNATRGIRRGPYSA AKGGINALTQSLAMEYGEQGIRVVATAPGGTSAPARKVPRNAEGDSAQEQAWMAEAVEQVTRSTFMKRYGTLEEQIAPIL FLASDEASYITGTVLPVAGGDLG >Mature_262_residues SEYGAHFAGRFDGKVMVVTGAAQGIGRGVAERAAAEGAQVLLVDRADFVTDVAAAIGPKAHAFVADLEGHAGAAAAVAHG LAVFGRIDILINNVGGAIRMRPYDQFTSEQIDAEIRRSLMPTLYCCHAVLPPMLAQGAGTIVNVSSNATRGIRRGPYSAA KGGINALTQSLAMEYGEQGIRVVATAPGGTSAPARKVPRNAEGDSAQEQAWMAEAVEQVTRSTFMKRYGTLEEQIAPILF LASDEASYITGTVLPVAGGDLG
Specific function: Degradation of 2-hydro-1,2-dihydroxy benzoate (DHB) to catechol [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=29.6, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.8880308880309, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=268, Percent_Identity=30.2238805970149, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=30.1960784313725, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=27.7992277992278, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI5031737, Length=268, Percent_Identity=29.1044776119403, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=32.6530612244898, Blast_Score=69, Evalue=3e-12, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.976833976834, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=31.1284046692607, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=28.8461538461538, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=29.9610894941634, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.6274509803922, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI2367175, Length=263, Percent_Identity=30.0380228136882, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=29.5019157088123, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.1338582677165, Blast_Score=67, Evalue=9e-13, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=29.0076335877863, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=26.7716535433071, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=24.9027237354086, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=26.5536723163842, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI71994600, Length=269, Percent_Identity=31.2267657992565, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=32.089552238806, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=26.4822134387352, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=30.2583025830258, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=28.8389513108614, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71994604, Length=268, Percent_Identity=28.7313432835821, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562904, Length=201, Percent_Identity=31.8407960199005, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=31.3653136531365, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=31.0861423220974, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=29.5719844357977, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.5185185185185, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=203, Percent_Identity=30.5418719211823, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17563726, Length=191, Percent_Identity=31.413612565445, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17531453, Length=193, Percent_Identity=32.1243523316062, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=29.0909090909091, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=27.8810408921933, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=27.8810408921933, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562908, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI25152911, Length=201, Percent_Identity=34.3283582089552, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=272, Percent_Identity=25, Blast_Score=70, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=31, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=32.1705426356589, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=34.9019607843137, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=32.0610687022901, Blast_Score=102, Evalue=4e-22, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=31.2741312741313, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=29.718875502008, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=30.7984790874525, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=32.824427480916, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=31.1557788944724, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=31.25, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=9e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.25 [H]
Molecular weight: Translated: 27314; Mature: 27183
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSEYGAHFAGRFDGKVMVVTGAAQGIGRGVAERAAAEGAQVLLVDRADFVTDVAAAIGPK CCCCCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCC AHAFVADLEGHAGAAAAVAHGLAVFGRIDILINNVGGAIRMRPYDQFTSEQIDAEIRRSL HHEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH MPTLYCCHAVLPPMLAQGAGTIVNVSSNATRGIRRGPYSAAKGGINALTQSLAMEYGEQG HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCCCHHHHCCHHHHHHHHHHHHCCCC IRVVATAPGGTSAPARKVPRNAEGDSAQEQAWMAEAVEQVTRSTFMKRYGTLEEQIAPIL CEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE FLASDEASYITGTVLPVAGGDLG EEECCCCCEEEEEEEEECCCCCC >Mature Secondary Structure SEYGAHFAGRFDGKVMVVTGAAQGIGRGVAERAAAEGAQVLLVDRADFVTDVAAAIGPK CCCCCCCCEECCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHCCC AHAFVADLEGHAGAAAAVAHGLAVFGRIDILINNVGGAIRMRPYDQFTSEQIDAEIRRSL HHEEEEECCCCCCHHHHHHHHHHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH MPTLYCCHAVLPPMLAQGAGTIVNVSSNATRGIRRGPYSAAKGGINALTQSLAMEYGEQG HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHCCCCHHHHCCHHHHHHHHHHHHCCCC IRVVATAPGGTSAPARKVPRNAEGDSAQEQAWMAEAVEQVTRSTFMKRYGTLEEQIAPIL CEEEEECCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEE FLASDEASYITGTVLPVAGGDLG EEECCCCCEEEEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1740120 [H]