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The map label for this gene is pkn1 [H]

Identifier: 87198560

GI number: 87198560

Start: 585343

End: 586290

Strand: Direct

Name: pkn1 [H]

Synonym: Saro_0536

Alternate gene names: 87198560

Gene position: 585343-586290 (Clockwise)

Preceding gene: 87198559

Following gene: 87198562

Centisome position: 16.43

GC content: 63.5

Gene sequence:

>948_bases
GTGTCCAGGGAAGCGGAACAGCGGCATGCCGGAATGCGCCTGATCGAAGGCGGCACGTTCCTCATGGGCTCCGAGGCATT
CTACCCGGAAGAGGCGCCCGTGCGCCGCGTCAGGGTCGACAGCTTCTGGATCGACGAGACACCTGTAACCAACTTTCAGT
TCGCCGCCTTCATCGAGGCGACAGGCTACGTCACGGTTGCCGAGGTCGCACCTGATCCGAAGGACTATCCTGGCATGATA
CCGGGTATGGACCGGGCCGGATCGCTCGTCTTCCAGAAGACGTCGGGACCCGTCGACATGGCGGATGCTTCCAATTGGTG
GCGTTTTACCTTCGGGGCTTGCTGGAAGCATCCACTTGGCCCCGGCAGCGACCTCGCCGGGCTCGAAGACCATCCGGTGG
TCCATGTCGCATATCCCGATGCAGAGGCTTACGCGACCTGGGCGGGCAAGTGCCTGCCGACCGAGGCGGAGTTCGAATTC
GCCGCGCGCGGGGGGCTCGATGGCCAGGACTATGCGTGGGGTTCCGAACTGGCGCCCGATGGCCGGATGATGGCCAACTA
CTGGCAGGGCCTGTTCCCTTTCGCCAATCAATGCCTCGATGGATGGGAGCGCACGTCGCCGGTGCGAAGCTTTCCTCCCA
ATGGTCATGGCGTTTACGACATGATCGGCAACACCTGGGAATGGACTTCCGACTGGTGGACCGCGAAGCCCATGCCCCCG
AAGGCGAAGAGGTCATGCTGCCCGATCGACAATCCGCGAGGTGGCAGGCTCAGGGAAAGTTTCGACCCGGACCATCCGGG
CGTCCGTATCGGTCGCAAGGTCATCAAGGGCGGGTCGCACTTGTGCGCCGCCAACTACTGCCAGCGCTATCGCCCCGCCG
CGCGGCATCCGGAAATGGTCGATACCGCCACCTCCCACATCGGCTTCAGGTGTGTTGTCCGGGGATGA

Upstream 100 bases:

>100_bases
GGGCGCGCTTGCGGCAGACGAAGCGCAAGCTTCGTCTGCCTTGCGAAATGGCAAGGAGGCCGGGCCGCGTGAAGCGTGGC
CTTCGGTGGAGCGAAGCAAG

Downstream 100 bases:

>100_bases
CCGGACAGGATGCGCGCCCCGGTTCTCCGAACACCCGGTTCCAGTTTCGGCATTCCGGGATCAGGGGGCGGAGTGGGCGA
GGATTTCGGGTACGGGGTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSREAEQRHAGMRLIEGGTFLMGSEAFYPEEAPVRRVRVDSFWIDETPVTNFQFAAFIEATGYVTVAEVAPDPKDYPGMI
PGMDRAGSLVFQKTSGPVDMADASNWWRFTFGACWKHPLGPGSDLAGLEDHPVVHVAYPDAEAYATWAGKCLPTEAEFEF
AARGGLDGQDYAWGSELAPDGRMMANYWQGLFPFANQCLDGWERTSPVRSFPPNGHGVYDMIGNTWEWTSDWWTAKPMPP
KAKRSCCPIDNPRGGRLRESFDPDHPGVRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATSHIGFRCVVRG

Sequences:

>Translated_315_residues
MSREAEQRHAGMRLIEGGTFLMGSEAFYPEEAPVRRVRVDSFWIDETPVTNFQFAAFIEATGYVTVAEVAPDPKDYPGMI
PGMDRAGSLVFQKTSGPVDMADASNWWRFTFGACWKHPLGPGSDLAGLEDHPVVHVAYPDAEAYATWAGKCLPTEAEFEF
AARGGLDGQDYAWGSELAPDGRMMANYWQGLFPFANQCLDGWERTSPVRSFPPNGHGVYDMIGNTWEWTSDWWTAKPMPP
KAKRSCCPIDNPRGGRLRESFDPDHPGVRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATSHIGFRCVVRG
>Mature_314_residues
SREAEQRHAGMRLIEGGTFLMGSEAFYPEEAPVRRVRVDSFWIDETPVTNFQFAAFIEATGYVTVAEVAPDPKDYPGMIP
GMDRAGSLVFQKTSGPVDMADASNWWRFTFGACWKHPLGPGSDLAGLEDHPVVHVAYPDAEAYATWAGKCLPTEAEFEFA
ARGGLDGQDYAWGSELAPDGRMMANYWQGLFPFANQCLDGWERTSPVRSFPPNGHGVYDMIGNTWEWTSDWWTAKPMPPK
AKRSCCPIDNPRGGRLRESFDPDHPGVRIGRKVIKGGSHLCAANYCQRYRPAARHPEMVDTATSHIGFRCVVRG

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=313, Percent_Identity=41.2140575079872, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI257470975, Length=313, Percent_Identity=39.297124600639, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI257470977, Length=313, Percent_Identity=38.6581469648562, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI194248088, Length=305, Percent_Identity=35.0819672131148, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI194248087, Length=305, Percent_Identity=33.7704918032787, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI226437577, Length=209, Percent_Identity=37.799043062201, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI194248090, Length=205, Percent_Identity=40, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI20130397, Length=311, Percent_Identity=37.620578778135, Blast_Score=198, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 35042; Mature: 34910

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREAEQRHAGMRLIEGGTFLMGSEAFYPEEAPVRRVRVDSFWIDETPVTNFQFAAFIEA
CCCHHHHHHCCCEEECCCCEEECCCCCCCCCCCCEEEEECEEECCCCCCCCEEEEEEEEE
TGYVTVAEVAPDPKDYPGMIPGMDRAGSLVFQKTSGPVDMADASNWWRFTFGACWKHPLG
CCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCEEEEHHHHHCCCCC
PGSDLAGLEDHPVVHVAYPDAEAYATWAGKCLPTEAEFEFAARGGLDGQDYAWGSELAPD
CCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
GRMMANYWQGLFPFANQCLDGWERTSPVRSFPPNGHGVYDMIGNTWEWTSDWWTAKPMPP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCCCEECCCCCC
KAKRSCCPIDNPRGGRLRESFDPDHPGVRIGRKVIKGGSHLCAANYCQRYRPAARHPEMV
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHH
DTATSHIGFRCVVRG
HHHHHCCCEEEEECC
>Mature Secondary Structure 
SREAEQRHAGMRLIEGGTFLMGSEAFYPEEAPVRRVRVDSFWIDETPVTNFQFAAFIEA
CCHHHHHHCCCEEECCCCEEECCCCCCCCCCCCEEEEECEEECCCCCCCCEEEEEEEEE
TGYVTVAEVAPDPKDYPGMIPGMDRAGSLVFQKTSGPVDMADASNWWRFTFGACWKHPLG
CCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCEEEEHHHHHCCCCC
PGSDLAGLEDHPVVHVAYPDAEAYATWAGKCLPTEAEFEFAARGGLDGQDYAWGSELAPD
CCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCC
GRMMANYWQGLFPFANQCLDGWERTSPVRSFPPNGHGVYDMIGNTWEWTSDWWTAKPMPP
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEECCCCCEECCCCCC
KAKRSCCPIDNPRGGRLRESFDPDHPGVRIGRKVIKGGSHLCAANYCQRYRPAARHPEMV
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHH
DTATSHIGFRCVVRG
HHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]