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The map label for this gene is rnr [H]

Identifier: 87198528

GI number: 87198528

Start: 545339

End: 546724

Strand: Direct

Name: rnr [H]

Synonym: Saro_0503

Alternate gene names: 87198528

Gene position: 545339-546724 (Clockwise)

Preceding gene: 87198527

Following gene: 87198529

Centisome position: 15.31

GC content: 69.05

Gene sequence:

>1386_bases
ATGAGAGCCATCCACGATCCCCACGGCGCGCTGGCCGGCGGGCTTGCCGCCATCCGCGCGCAGTACCAGATCCCGGCAGG
CTTCACGCCCGAGGTTCTGGCCGCTGCCGAGGCCGCCGCGCAAAAGGCGCCTGCCGGGCACGCGGATCGCACCGAGATAC
CCTTCGTCACGCTCGATCCGGCCAGTTCCACCGACCTCGACCAGGCCTTCTGGATCGAGCCATCGGGAAGCGATCTAGTC
CTGCGCTATGCGATCGCGGATGTCGCATGGTTCGTGAGCGACGGCGATGCCGTGGATGCCGAGGCCTGGAAGCGGGGCGA
GACGATCTACCTTCCGGAAGGCAAGGCGGGTCTCTATCCCCCGATCCTGTCGGAACGCGCCGCCAGCCTCCTGCCAGATG
GTCCGCGGCCTGCGGTCGTGTTTACGGTGAGGCTCGGCAGCGATGGCGAATGCCGCCTGGAAGGCGCCGAGCGCGCAATC
GTCCGCAGCCGCGCAAAGCTCGCCTACGACAACGTTCGCGACGAGGACATGCCAGCCGGCTTCGCCGAGTTTGCCGCGCG
GGTGAATGCGGCCGAGGCTGCGCGCGGAGCCGCCCGGGTCGATCCTCCGGAACAGGAGGTCGAACCTTTGGGCGACGGCC
GCTACGCCCTGCGCCTCCGTCCACTTCTGCTGTCGGAAAGGCGCAATGCCGCACTTTCGCTGGCGACGAACCTTGCGGTC
GCCGATGCCTTGCAGACGGCGGGCACGGGGCTGTTCCGGGTCATGGCCGGGCCGAGCGCGAAGGCCATGGCGCGTCTTCG
CTCGACGGCGGCCGGTCTCGGGCTGGACTGGCCGGCGGACATCGACCTGAAGGCGCTCGAACGGACGCTCGACCAGAAAA
ATCCGCATCACGCCGCCTTCATGCTGGCGGTGCGCCGCGCCGGGAACGGGGCAGGCTATGCGCCGTGGATACCTGGCGTC
ACCCCCTGGCACGAGGCAGTGGCGGCCACCTATGCCCATGCCACCGCACCTCTGCGTCGACTGGCGGACCGGTATGTGAT
CCGCGCGGCCCTTGCGGTCATGGCGGGGCGCCCTGTACCTGCGGAGGTCGAGGATGCCTTTCGCCGACTTCCCGCGGTCA
TGGCCAAGGCCGAGGCGACCTCCGGCCAGATCGAGCGGGCAGTTATCGACCTGGCCGAGGCGGTGATGCTTCAGGGCCGG
GAGGGCGAGCGCTTTGCCGCTTGCGTGACCGACATCGATGGCGACTCGGCGCGCATCCACCTTGCGGACCTGCCTGTCGT
CGGCCGAACCCGAATTCCCGGGGCGACGCCTGGCCAAAGGGTCGACTTGCGCCTTGACGGCGTCGATCTGAGCACGCGAC
GGCTTACTTTCAGCGCCGCCGACTGA

Upstream 100 bases:

>100_bases
CGCAACCAGATGGAAGCGGTGAAGGCAGGCATGGAAAAGCGAGCCGGGGATTTCGTCGATCCATGACCCTGACGGCAATG
ACCCAGGTTAAAGGTCCGGC

Downstream 100 bases:

>100_bases
CGATCATGCCCGTGATGCAAGAACCCCTTGCGGCATTGCCCGCTTCCGGCTAACCGCGCCAAACCACGCAGCTCCTGCGA
TCGAGGCCCGATGGCGGAGT

Product: ribonuclease II

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRAIHDPHGALAGGLAAIRAQYQIPAGFTPEVLAAAEAAAQKAPAGHADRTEIPFVTLDPASSTDLDQAFWIEPSGSDLV
LRYAIADVAWFVSDGDAVDAEAWKRGETIYLPEGKAGLYPPILSERAASLLPDGPRPAVVFTVRLGSDGECRLEGAERAI
VRSRAKLAYDNVRDEDMPAGFAEFAARVNAAEAARGAARVDPPEQEVEPLGDGRYALRLRPLLLSERRNAALSLATNLAV
ADALQTAGTGLFRVMAGPSAKAMARLRSTAAGLGLDWPADIDLKALERTLDQKNPHHAAFMLAVRRAGNGAGYAPWIPGV
TPWHEAVAATYAHATAPLRRLADRYVIRAALAVMAGRPVPAEVEDAFRRLPAVMAKAEATSGQIERAVIDLAEAVMLQGR
EGERFAACVTDIDGDSARIHLADLPVVGRTRIPGATPGQRVDLRLDGVDLSTRRLTFSAAD

Sequences:

>Translated_461_residues
MRAIHDPHGALAGGLAAIRAQYQIPAGFTPEVLAAAEAAAQKAPAGHADRTEIPFVTLDPASSTDLDQAFWIEPSGSDLV
LRYAIADVAWFVSDGDAVDAEAWKRGETIYLPEGKAGLYPPILSERAASLLPDGPRPAVVFTVRLGSDGECRLEGAERAI
VRSRAKLAYDNVRDEDMPAGFAEFAARVNAAEAARGAARVDPPEQEVEPLGDGRYALRLRPLLLSERRNAALSLATNLAV
ADALQTAGTGLFRVMAGPSAKAMARLRSTAAGLGLDWPADIDLKALERTLDQKNPHHAAFMLAVRRAGNGAGYAPWIPGV
TPWHEAVAATYAHATAPLRRLADRYVIRAALAVMAGRPVPAEVEDAFRRLPAVMAKAEATSGQIERAVIDLAEAVMLQGR
EGERFAACVTDIDGDSARIHLADLPVVGRTRIPGATPGQRVDLRLDGVDLSTRRLTFSAAD
>Mature_461_residues
MRAIHDPHGALAGGLAAIRAQYQIPAGFTPEVLAAAEAAAQKAPAGHADRTEIPFVTLDPASSTDLDQAFWIEPSGSDLV
LRYAIADVAWFVSDGDAVDAEAWKRGETIYLPEGKAGLYPPILSERAASLLPDGPRPAVVFTVRLGSDGECRLEGAERAI
VRSRAKLAYDNVRDEDMPAGFAEFAARVNAAEAARGAARVDPPEQEVEPLGDGRYALRLRPLLLSERRNAALSLATNLAV
ADALQTAGTGLFRVMAGPSAKAMARLRSTAAGLGLDWPADIDLKALERTLDQKNPHHAAFMLAVRRAGNGAGYAPWIPGV
TPWHEAVAATYAHATAPLRRLADRYVIRAALAVMAGRPVPAEVEDAFRRLPAVMAKAEATSGQIERAVIDLAEAVMLQGR
EGERFAACVTDIDGDSARIHLADLPVVGRTRIPGATPGQRVDLRLDGVDLSTRRLTFSAAD

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=341, Percent_Identity=23.7536656891496, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI190014625, Length=341, Percent_Identity=23.7536656891496, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87082383, Length=502, Percent_Identity=24.7011952191235, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787542, Length=400, Percent_Identity=25.75, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212645896, Length=331, Percent_Identity=25.0755287009063, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 48995; Mature: 48995

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIHDPHGALAGGLAAIRAQYQIPAGFTPEVLAAAEAAAQKAPAGHADRTEIPFVTLDP
CCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
ASSTDLDQAFWIEPSGSDLVLRYAIADVAWFVSDGDAVDAEAWKRGETIYLPEGKAGLYP
CCCCCCCCEEEECCCCCCEEEEEEHHHHHEEECCCCCCCHHHHHCCCEEEECCCCCCCCC
PILSERAASLLPDGPRPAVVFTVRLGSDGECRLEGAERAIVRSRAKLAYDNVRDEDMPAG
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCC
FAEFAARVNAAEAARGAARVDPPEQEVEPLGDGRYALRLRPLLLSERRNAALSLATNLAV
HHHHHHHHCHHHHHCCCCCCCCCHHHHCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ADALQTAGTGLFRVMAGPSAKAMARLRSTAAGLGLDWPADIDLKALERTLDQKNPHHAAF
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
MLAVRRAGNGAGYAPWIPGVTPWHEAVAATYAHATAPLRRLADRYVIRAALAVMAGRPVP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEVEDAFRRLPAVMAKAEATSGQIERAVIDLAEAVMLQGREGERFAACVTDIDGDSARIH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEE
LADLPVVGRTRIPGATPGQRVDLRLDGVDLSTRRLTFSAAD
EECCCEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MRAIHDPHGALAGGLAAIRAQYQIPAGFTPEVLAAAEAAAQKAPAGHADRTEIPFVTLDP
CCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
ASSTDLDQAFWIEPSGSDLVLRYAIADVAWFVSDGDAVDAEAWKRGETIYLPEGKAGLYP
CCCCCCCCEEEECCCCCCEEEEEEHHHHHEEECCCCCCCHHHHHCCCEEEECCCCCCCCC
PILSERAASLLPDGPRPAVVFTVRLGSDGECRLEGAERAIVRSRAKLAYDNVRDEDMPAG
CHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCC
FAEFAARVNAAEAARGAARVDPPEQEVEPLGDGRYALRLRPLLLSERRNAALSLATNLAV
HHHHHHHHCHHHHHCCCCCCCCCHHHHCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHH
ADALQTAGTGLFRVMAGPSAKAMARLRSTAAGLGLDWPADIDLKALERTLDQKNPHHAAF
HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
MLAVRRAGNGAGYAPWIPGVTPWHEAVAATYAHATAPLRRLADRYVIRAALAVMAGRPVP
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEVEDAFRRLPAVMAKAEATSGQIERAVIDLAEAVMLQGREGERFAACVTDIDGDSARIH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEE
LADLPVVGRTRIPGATPGQRVDLRLDGVDLSTRRLTFSAAD
EECCCEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]