Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 87198466

GI number: 87198466

Start: 480687

End: 481424

Strand: Direct

Name: ompR [H]

Synonym: Saro_0441

Alternate gene names: 87198466

Gene position: 480687-481424 (Clockwise)

Preceding gene: 87198465

Following gene: 87198467

Centisome position: 13.5

GC content: 63.96

Gene sequence:

>738_bases
ATGAACGAAGCGCCGATCCGCATTCTCCTGGTGGATGACGAACCGGCCCTGCGCGAACCCCTGGCGGACTATCTGGTCCG
CCAGGGGTTCGTCGTAACGCAGGCCGGTACTGCCGCCGAAGCACGCAGCCGTTTACTTGAAACCGGTTGCGACCTGGTCC
TGCTCGACATCATGATGCCGGGCGAAGACGGGCTGTCGCTGTGCCGCCATCTTGTGGAATCGAAGCGGCTTCCGGTCATT
TTCATCACCGCGAAGGGCGAATCCACCGATCGCATCGTCGGGCTGGAAATCGGTGCCGACGACTATGTCGTGAAGCCCTT
CGACCCGCGCGAACTCGTCGCCCGCATCCGTTCGGTCCTGCGCCGCGCAACCAAGCAGTCGAGCGAGGTTTCGGACGAGG
TCATCTATGAATTCGAGGGCTGGCGGCTCGATCCGCTCAAGCGCCGGCTGATCGATGCCGAAGGCGCGGTCGTCGCCATA
TCCTCGGCCGAGTTCCGCCTGCTCATGGCTTTCCTCGACCATCCCCGCCAGGTCCTCGATCGCGATCGTCTGCTCGATAT
GGTCCAGGGCCGTGAAGCGCACCTGTTCGACCGCGCGGTGGACAACCAGATTTCGCGCCTGCGCCGAAAGATCGAGGTCG
ACAGCCGCAATCCGGAACTGATCCAGACCGTCTGGGGTGGCGGCTACATGCTCGCCGCCGAAGTCCGCAAGCGCGCCGCC
GTCGAAGGCGAAGCCTGA

Upstream 100 bases:

>100_bases
TGAAGGAAATGATGGGCAAGATGGGCCGCCCCGGCGAACGTGGCCCGATGGGCGCAATGGGCGATGGACCTCCGCCCCCG
CCTCCGGCTAACTGATTGCC

Downstream 100 bases:

>100_bases
ACCGTGCGAGCCTTGCGCCTCTGGCCCCGTAGCCTGCAGGGACAGGTCCTGCTGGCGATTGCCTTCGCCCTGCTGATCGC
GCAGACGATCTCGGCGGTGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNEAPIRILLVDDEPALREPLADYLVRQGFVVTQAGTAAEARSRLLETGCDLVLLDIMMPGEDGLSLCRHLVESKRLPVI
FITAKGESTDRIVGLEIGADDYVVKPFDPRELVARIRSVLRRATKQSSEVSDEVIYEFEGWRLDPLKRRLIDAEGAVVAI
SSAEFRLLMAFLDHPRQVLDRDRLLDMVQGREAHLFDRAVDNQISRLRRKIEVDSRNPELIQTVWGGGYMLAAEVRKRAA
VEGEA

Sequences:

>Translated_245_residues
MNEAPIRILLVDDEPALREPLADYLVRQGFVVTQAGTAAEARSRLLETGCDLVLLDIMMPGEDGLSLCRHLVESKRLPVI
FITAKGESTDRIVGLEIGADDYVVKPFDPRELVARIRSVLRRATKQSSEVSDEVIYEFEGWRLDPLKRRLIDAEGAVVAI
SSAEFRLLMAFLDHPRQVLDRDRLLDMVQGREAHLFDRAVDNQISRLRRKIEVDSRNPELIQTVWGGGYMLAAEVRKRAA
VEGEA
>Mature_245_residues
MNEAPIRILLVDDEPALREPLADYLVRQGFVVTQAGTAAEARSRLLETGCDLVLLDIMMPGEDGLSLCRHLVESKRLPVI
FITAKGESTDRIVGLEIGADDYVVKPFDPRELVARIRSVLRRATKQSSEVSDEVIYEFEGWRLDPLKRRLIDAEGAVVAI
SSAEFRLLMAFLDHPRQVLDRDRLLDMVQGREAHLFDRAVDNQISRLRRKIEVDSRNPELIQTVWGGGYMLAAEVRKRAA
VEGEA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=46.1538461538462, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.8695652173913, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=38.6266094420601, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1788394, Length=248, Percent_Identity=37.0967741935484, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=38.034188034188, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=37.8260869565217, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=37.0044052863436, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=235, Percent_Identity=36.5957446808511, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=31.3304721030043, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=31.8777292576419, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.6666666666667, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=31.4655172413793, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.0043668122271, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=32.1739130434783, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=39.2523364485981, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27604; Mature: 27604

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAPIRILLVDDEPALREPLADYLVRQGFVVTQAGTAAEARSRLLETGCDLVLLDIMMP
CCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECC
GEDGLSLCRHLVESKRLPVIFITAKGESTDRIVGLEIGADDYVVKPFDPRELVARIRSVL
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHH
RRATKQSSEVSDEVIYEFEGWRLDPLKRRLIDAEGAVVAISSAEFRLLMAFLDHPRQVLD
HHHHHHHHCCCHHHEEEECCCEECHHHHHHHCCCCCEEEECCHHHHHHHHHHHCHHHHHH
RDRLLDMVQGREAHLFDRAVDNQISRLRRKIEVDSRNPELIQTVWGGGYMLAAEVRKRAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHC
VEGEA
CCCCC
>Mature Secondary Structure
MNEAPIRILLVDDEPALREPLADYLVRQGFVVTQAGTAAEARSRLLETGCDLVLLDIMMP
CCCCCEEEEEECCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECC
GEDGLSLCRHLVESKRLPVIFITAKGESTDRIVGLEIGADDYVVKPFDPRELVARIRSVL
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHH
RRATKQSSEVSDEVIYEFEGWRLDPLKRRLIDAEGAVVAISSAEFRLLMAFLDHPRQVLD
HHHHHHHHCCCHHHEEEECCCEECHHHHHHHCCCCCEEEECCHHHHHHHHHHHCHHHHHH
RDRLLDMVQGREAHLFDRAVDNQISRLRRKIEVDSRNPELIQTVWGGGYMLAAEVRKRAA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEHHHHHHHHC
VEGEA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]