Click here to switch to the map view.

The map label for this gene is 87198459

Identifier: 87198459

GI number: 87198459

Start: 471997

End: 472533

Strand: Direct

Name: 87198459

Synonym: Saro_0434

Alternate gene names: NA

Gene position: 471997-472533 (Clockwise)

Preceding gene: 87198457

Following gene: 87198460

Centisome position: 13.25

GC content: 71.69

Gene sequence:

>537_bases
ATGGCAAAGCGCCAGACCATCCAGCGCGCGCGTGCGCCGCATCTGATCCTGCTCAGCGATGCACGCAACGATGCGGCGCT
GGCCCGCGCGATCGCGCGGCTGCCGCGCGGGTCGGCGCTGGTCTTCCGGCACTATCACCTGCCTGCTCACGAACGGCGGC
GGCGCTTTGCGGAACTGCGCCGGCTGGCAAGAGCGCGCGGCATCTCGATGATCGGCGCGCGCGTTCCCACCGCCTGGGGG
GGCGAGGGCGTCTACGGAACTGCGCGCGAGGTGGCGGGAAGGCGGGGTATCCGGCTTGCCACCGCCCACTCGCTCGGTGA
AGTCGCTGCCGCAGCGAGAGCAGGTGCCGACGCGGTCCTGCTATCCCCGGTTCATCCTACTCGCTCACATCCGGGAGCGC
CGGTACTGGGCCCGGTGCGCTTCCTGCTGCTCGCGCGCCGGTCTCCGCTGCCGGTGATCGCGCTTGGCGGTATGACGGCG
CGGCGTGCGGCGCGCTTGCCGGTGCATGGCTGGGCGGCTATCGACGGCCTCGCTTAA

Upstream 100 bases:

>100_bases
GCGACCGGCGATGCGGGCTGCGGAAGCGATGCGGGCGCGAACCGCATCGAGCGGCGATGAAGGGACTGCCTGTTCCATGG
CGCGGTGCTATAGCGCCGGG

Downstream 100 bases:

>100_bases
GCCATTGCTCCAGCGCGATTCCCCGCGGGATTCTTGACGCTGACTCCCTAACCGGCGCATGATGGCCAAAGCAAGGGCAG
GGATACGCGCAATCATGGCT

Product: thiamine monophosphate synthase

Products: diphosphate; thiamine monophosphate

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MAKRQTIQRARAPHLILLSDARNDAALARAIARLPRGSALVFRHYHLPAHERRRRFAELRRLARARGISMIGARVPTAWG
GEGVYGTAREVAGRRGIRLATAHSLGEVAAAARAGADAVLLSPVHPTRSHPGAPVLGPVRFLLLARRSPLPVIALGGMTA
RRAARLPVHGWAAIDGLA

Sequences:

>Translated_178_residues
MAKRQTIQRARAPHLILLSDARNDAALARAIARLPRGSALVFRHYHLPAHERRRRFAELRRLARARGISMIGARVPTAWG
GEGVYGTAREVAGRRGIRLATAHSLGEVAAAARAGADAVLLSPVHPTRSHPGAPVLGPVRFLLLARRSPLPVIALGGMTA
RRAARLPVHGWAAIDGLA
>Mature_177_residues
AKRQTIQRARAPHLILLSDARNDAALARAIARLPRGSALVFRHYHLPAHERRRRFAELRRLARARGISMIGARVPTAWGG
EGVYGTAREVAGRRGIRLATAHSLGEVAAAARAGADAVLLSPVHPTRSHPGAPVLGPVRFLLLARRSPLPVIALGGMTAR
RAARLPVHGWAAIDGLA

Specific function: Unknown

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.3

Molecular weight: Translated: 19066; Mature: 18934

Theoretical pI: Translated: 12.65; Mature: 12.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRQTIQRARAPHLILLSDARNDAALARAIARLPRGSALVFRHYHLPAHERRRRFAELR
CCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
RLARARGISMIGARVPTAWGGEGVYGTAREVAGRRGIRLATAHSLGEVAAAARAGADAVL
HHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEE
LSPVHPTRSHPGAPVLGPVRFLLLARRSPLPVIALGGMTARRAARLPVHGWAAIDGLA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCHHCCCCC
>Mature Secondary Structure 
AKRQTIQRARAPHLILLSDARNDAALARAIARLPRGSALVFRHYHLPAHERRRRFAELR
CCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
RLARARGISMIGARVPTAWGGEGVYGTAREVAGRRGIRLATAHSLGEVAAAARAGADAVL
HHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCEEE
LSPVHPTRSHPGAPVLGPVRFLLLARRSPLPVIALGGMTARRAARLPVHGWAAIDGLA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate; 4-Methyl-5-(2-phosphono-oxyethyl)-thiazole

Specific reaction: 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)thiazole = diphosphate + thiamine monophosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA