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The map label for this gene is tldD [H]

Identifier: 87198438

GI number: 87198438

Start: 452563

End: 454002

Strand: Direct

Name: tldD [H]

Synonym: Saro_0413

Alternate gene names: 87198438

Gene position: 452563-454002 (Clockwise)

Preceding gene: 87198437

Following gene: 87198439

Centisome position: 12.71

GC content: 67.15

Gene sequence:

>1440_bases
ATGACCGATCCCGACACGCGCTCGCTGCTCTACCGCTCTGGCCTGCTCACCCCGGATGATGCCCGGCGCCTCACGCGCGA
TGCGCTGACGGCCTGCGACGATGGCGAGCTCTATCTCCAGTTCATCGCCAGCGAGAGTTTCGGGTTCGACGACGGTCGGC
TGAAGACTGCCGACTATTCCCGTGACGCCGGTTTCGGCCTGCGGGGCGTTTCGGGCGAAATGACCGGCTTTGCCCATGCC
AACGAGATTTCCGCCGCCGCCATCGCCCGCGCCGGCGAGACGCTGAAGCTGCTCGACCCGGCAAAGGGCCAGCCCGCTCC
GCCGCCGCGCAACAACAACCGCCATCTCTACACCGAAGCCTCCCCGCTCGATGCCGTGCCGTTCGAGGCCAAGGTTCGCC
TGCTCGAATCGATCGACGCTGCCGCTCGCGCCCGCGATCCGCGCGTGGTGCAGGTCTCGGCCTCGCTCGCGGGATCGTGG
TCGGTCGTGGAAATCGTGCGCCCGGATGGTTTCGTCGCCCACGACGTGCGGCCGCTCGTCCGCCTCAACGTCTCGATCGT
CGCGGAAAAGGATGGCCGGCGCGAGACCGGTTCCTTTGGTATCGGCGGCCGGCGCCTCTACGACGATCTCTTCGCACCCG
AAACCTGGAGCCGCGCTATCGACGAGGCGCTTTCCCAGGCGCTCGTGAACCTCGAATCGGTCGCGGCCCCGGCGGGCGAG
ATGACCGTGCTGCTTGGCCCGGGCTGGCCCGGCGTTCTCCTCCACGAAGCTGTCGGCCACGGCCTGGAAGGCGATTTCAA
CCGCAAGGGAACCAGCGCGTTCTCGGGCCGCATCGGCCAGCGCGTCGCTGCACCCGGGGTGACCGTGATCGATGACGGCA
CGTTGCTTGGCGTCAATGGGCAGGGCCGCCGCGGCTCGCTCTCCATCGACGACGAGGGCACGCCAACCCAGGAGAACATC
CTGATCGAGGACGGCATTCTCAAGGGCTACATCCAGGATCGCCTCAATGCCCGGCTCATGGGCGTGGCGCCCACCGGTAA
CGGTCGGCGCGAATCCTATGCCCATGCCCCCATGCCGCGCATGACCAACACCTTTATGCGCGCAGGCAACGACGATCCCG
CAGAACTGCTCTCTCGCGTGAAGAACGGCATCTTTGCCAAGTCTTTCGGCGGCGGGCAGGTCGACATAACCAGCGGCAAG
TTCGTGTTCTCCTGCACCGAGGCCTATCACATCGAGAACGGCAGGCTCGGCGCGCCGATCAAGGGCGCGACTCTGATTGG
CGACGGCCCGACCTGTCTCACCAAGGTCACCGGGATCGGCAACGACCTCGCCCTCGATGAAGGCGTCGGCGTCTGCGGCA
AGGGCGGGCAGAGCGTGCCGGCCGGCGTCGGACAGCCGACCTTGCTGGTCGAGGGTCTTACGGTGGGCGGTACGGCGTGA

Upstream 100 bases:

>100_bases
GCGGTCCTGCGGATACTGCGGCGGCTGCCTGAACGGCGTTGCGCTCGCAGGGGCATTGCGCTCTCTGGCCTTTGCTGGAT
GAGCGCTTATATCGGACGGC

Downstream 100 bases:

>100_bases
CCGAGGCGGGCGCGGAGATCACCGGGGGATGCCCCTGCGGTGCCCTCCGCTACCGCGCCGCCTAACACGGATTCGTGCCC
TATGCCTGCCACTGCCACGG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTDPDTRSLLYRSGLLTPDDARRLTRDALTACDDGELYLQFIASESFGFDDGRLKTADYSRDAGFGLRGVSGEMTGFAHA
NEISAAAIARAGETLKLLDPAKGQPAPPPRNNNRHLYTEASPLDAVPFEAKVRLLESIDAAARARDPRVVQVSASLAGSW
SVVEIVRPDGFVAHDVRPLVRLNVSIVAEKDGRRETGSFGIGGRRLYDDLFAPETWSRAIDEALSQALVNLESVAAPAGE
MTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVIDDGTLLGVNGQGRRGSLSIDDEGTPTQENI
LIEDGILKGYIQDRLNARLMGVAPTGNGRRESYAHAPMPRMTNTFMRAGNDDPAELLSRVKNGIFAKSFGGGQVDITSGK
FVFSCTEAYHIENGRLGAPIKGATLIGDGPTCLTKVTGIGNDLALDEGVGVCGKGGQSVPAGVGQPTLLVEGLTVGGTA

Sequences:

>Translated_479_residues
MTDPDTRSLLYRSGLLTPDDARRLTRDALTACDDGELYLQFIASESFGFDDGRLKTADYSRDAGFGLRGVSGEMTGFAHA
NEISAAAIARAGETLKLLDPAKGQPAPPPRNNNRHLYTEASPLDAVPFEAKVRLLESIDAAARARDPRVVQVSASLAGSW
SVVEIVRPDGFVAHDVRPLVRLNVSIVAEKDGRRETGSFGIGGRRLYDDLFAPETWSRAIDEALSQALVNLESVAAPAGE
MTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVIDDGTLLGVNGQGRRGSLSIDDEGTPTQENI
LIEDGILKGYIQDRLNARLMGVAPTGNGRRESYAHAPMPRMTNTFMRAGNDDPAELLSRVKNGIFAKSFGGGQVDITSGK
FVFSCTEAYHIENGRLGAPIKGATLIGDGPTCLTKVTGIGNDLALDEGVGVCGKGGQSVPAGVGQPTLLVEGLTVGGTA
>Mature_478_residues
TDPDTRSLLYRSGLLTPDDARRLTRDALTACDDGELYLQFIASESFGFDDGRLKTADYSRDAGFGLRGVSGEMTGFAHAN
EISAAAIARAGETLKLLDPAKGQPAPPPRNNNRHLYTEASPLDAVPFEAKVRLLESIDAAARARDPRVVQVSASLAGSWS
VVEIVRPDGFVAHDVRPLVRLNVSIVAEKDGRRETGSFGIGGRRLYDDLFAPETWSRAIDEALSQALVNLESVAAPAGEM
TVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVIDDGTLLGVNGQGRRGSLSIDDEGTPTQENIL
IEDGILKGYIQDRLNARLMGVAPTGNGRRESYAHAPMPRMTNTFMRAGNDDPAELLSRVKNGIFAKSFGGGQVDITSGKF
VFSCTEAYHIENGRLGAPIKGATLIGDGPTCLTKVTGIGNDLALDEGVGVCGKGGQSVPAGVGQPTLLVEGLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=483, Percent_Identity=52.7950310559006, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50431; Mature: 50300

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPDTRSLLYRSGLLTPDDARRLTRDALTACDDGELYLQFIASESFGFDDGRLKTADYS
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCC
RDAGFGLRGVSGEMTGFAHANEISAAAIARAGETLKLLDPAKGQPAPPPRNNNRHLYTEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEECC
SPLDAVPFEAKVRLLESIDAAARARDPRVVQVSASLAGSWSVVEIVRPDGFVAHDVRPLV
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEHHCCCEEE
RLNVSIVAEKDGRRETGSFGIGGRRLYDDLFAPETWSRAIDEALSQALVNLESVAAPAGE
EEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
MTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVIDDGTLLGVNG
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHCCCCCEEEECCEEEECCC
QGRRGSLSIDDEGTPTQENILIEDGILKGYIQDRLNARLMGVAPTGNGRRESYAHAPMPR
CCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCH
MTNTFMRAGNDDPAELLSRVKNGIFAKSFGGGQVDITSGKFVFSCTEAYHIENGRLGAPI
HHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCEEEEECCCEEEEEEEEEEECCCCCCCCC
KGATLIGDGPTCLTKVTGIGNDLALDEGVGVCGKGGQSVPAGVGQPTLLVEGLTVGGTA
CCCEEECCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TDPDTRSLLYRSGLLTPDDARRLTRDALTACDDGELYLQFIASESFGFDDGRLKTADYS
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCC
RDAGFGLRGVSGEMTGFAHANEISAAAIARAGETLKLLDPAKGQPAPPPRNNNRHLYTEA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEECC
SPLDAVPFEAKVRLLESIDAAARARDPRVVQVSASLAGSWSVVEIVRPDGFVAHDVRPLV
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCEEHHCCCEEE
RLNVSIVAEKDGRRETGSFGIGGRRLYDDLFAPETWSRAIDEALSQALVNLESVAAPAGE
EEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
MTVLLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGQRVAAPGVTVIDDGTLLGVNG
EEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHCCCCCEEEECCEEEECCC
QGRRGSLSIDDEGTPTQENILIEDGILKGYIQDRLNARLMGVAPTGNGRRESYAHAPMPR
CCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCH
MTNTFMRAGNDDPAELLSRVKNGIFAKSFGGGQVDITSGKFVFSCTEAYHIENGRLGAPI
HHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCEEEEECCCEEEEEEEEEEECCCCCCCCC
KGATLIGDGPTCLTKVTGIGNDLALDEGVGVCGKGGQSVPAGVGQPTLLVEGLTVGGTA
CCCEEECCCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]