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The map label for this gene is ahpC [C]

Identifier: 86751699

GI number: 86751699

Start: 5194961

End: 5195602

Strand: Reverse

Name: ahpC [C]

Synonym: RPB_4601

Alternate gene names: 86751699

Gene position: 5195602-5194961 (Counterclockwise)

Preceding gene: 86751702

Following gene: 86751698

Centisome position: 97.45

GC content: 65.42

Gene sequence:

>642_bases
ATGACCGATTTCGCCACGCCTGCCCCCCAACTCAACGCCCCCGCGCCCGCATTCAATGCACCGACCACCCATGGCCCCAA
GACGCTGGCCGATTACGCCGGCAAGTGGCTGATCCTGTTCTCGCATCCGGCGGATTTCACCCCGGTCTGCACCACCGAAT
TCATCGCCTTCGCCAAAAAGCACGACGCCTTTGCGGCGCGTGGTGCCGAGCTGCTCGGCCTGTCGATCGACAGTCACTAT
TCGCACATCGCCTGGATGCTGAACATCAAGGAGAAGTTCGGGGTCGAGATCAGATTTCCGATCATCGCCGACCTCAGCAT
GACCGTGGCCAGGGCGTACGGCATGATCCAGCCGGGTGCGTCCGACACGTCGGCGGTGCGCGCGACGTTCCTGATCGATC
CCGAAGGCAAGCTGCGCGCGATGGTCTACTACCCGATGATCGCCGGCCGTTCGGTCGACGAGATCTATCGGCTGCTGGTG
GCGCTGCAGACGGCCGACGCCAACAAGTGCGCGATGCCGGAGAGCTGGCAGCCGGGCGATGCGGTGATCGTGCCGCCCCC
GGCGACAGCGGCCGCTGCGCTCGCCCGCGCCGGTGAGGGCTACGACACGGTCGACTGGTACTACTCGACCCGCGCTCTCT
GA

Upstream 100 bases:

>100_bases
AGTTAGTCTATCACAGAAAGAAATATAATCAATTTCTCCAATCAGTCAGCCTCGCATACATCCGAGGTGCTCGGGACATC
CCGATCACCAGGAGACTGCA

Downstream 100 bases:

>100_bases
GGCTGCGCGCAAGCTCCGGCGCGCGCCGGAGCTCTTCCTTCAACTCATTCGTCTGATCATCACGGAGGATCAAGCCATGA
CCAATGCTGCGCAGACCACG

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDFATPAPQLNAPAPAFNAPTTHGPKTLADYAGKWLILFSHPADFTPVCTTEFIAFAKKHDAFAARGAELLGLSIDSHY
SHIAWMLNIKEKFGVEIRFPIIADLSMTVARAYGMIQPGASDTSAVRATFLIDPEGKLRAMVYYPMIAGRSVDEIYRLLV
ALQTADANKCAMPESWQPGDAVIVPPPATAAAALARAGEGYDTVDWYYSTRAL

Sequences:

>Translated_213_residues
MTDFATPAPQLNAPAPAFNAPTTHGPKTLADYAGKWLILFSHPADFTPVCTTEFIAFAKKHDAFAARGAELLGLSIDSHY
SHIAWMLNIKEKFGVEIRFPIIADLSMTVARAYGMIQPGASDTSAVRATFLIDPEGKLRAMVYYPMIAGRSVDEIYRLLV
ALQTADANKCAMPESWQPGDAVIVPPPATAAAALARAGEGYDTVDWYYSTRAL
>Mature_212_residues
TDFATPAPQLNAPAPAFNAPTTHGPKTLADYAGKWLILFSHPADFTPVCTTEFIAFAKKHDAFAARGAELLGLSIDSHYS
HIAWMLNIKEKFGVEIRFPIIADLSMTVARAYGMIQPGASDTSAVRATFLIDPEGKLRAMVYYPMIAGRSVDEIYRLLVA
LQTADANKCAMPESWQPGDAVIVPPPATAAAALARAGEGYDTVDWYYSTRAL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=195, Percent_Identity=40, Blast_Score=131, Evalue=4e-31,
Organism=Homo sapiens, GI32189392, Length=186, Percent_Identity=35.4838709677419, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI5453549, Length=161, Percent_Identity=37.888198757764, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=35.1648351648352, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=35.1648351648352, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=35.1648351648352, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI5802974, Length=203, Percent_Identity=31.5270935960591, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=33.5260115606936, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI33188454, Length=80, Percent_Identity=42.5, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786822, Length=159, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554494, Length=170, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193204376, Length=180, Percent_Identity=35.5555555555556, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32565831, Length=180, Percent_Identity=35.5555555555556, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25153706, Length=202, Percent_Identity=34.1584158415842, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319407, Length=201, Percent_Identity=42.7860696517413, Blast_Score=158, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6323613, Length=160, Percent_Identity=39.375, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320661, Length=160, Percent_Identity=35.625, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=38.5365853658537, Blast_Score=136, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24652434, Length=205, Percent_Identity=38.5365853658537, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652436, Length=205, Percent_Identity=38.5365853658537, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=34.0314136125654, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=34.0314136125654, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17157991, Length=187, Percent_Identity=37.4331550802139, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24641739, Length=187, Percent_Identity=37.4331550802139, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357347, Length=176, Percent_Identity=39.7727272727273, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI17738015, Length=198, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24581278, Length=197, Percent_Identity=35.5329949238579, Blast_Score=118, Evalue=3e-27,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23069; Mature: 22937

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFATPAPQLNAPAPAFNAPTTHGPKTLADYAGKWLILFSHPADFTPVCTTEFIAFAKK
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHH
HDAFAARGAELLGLSIDSHYSHIAWMLNIKEKFGVEIRFPIIADLSMTVARAYGMIQPGA
HHHHHHCCCEEEEEEECCCCCEEEEEEEEHHHHCCEEEECEEECHHHHHHHHHCCCCCCC
SDTSAVRATFLIDPEGKLRAMVYYPMIAGRSVDEIYRLLVALQTADANKCAMPESWQPGD
CCCCEEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
AVIVPPPATAAAALARAGEGYDTVDWYYSTRAL
EEEECCCCHHHHHHHHCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TDFATPAPQLNAPAPAFNAPTTHGPKTLADYAGKWLILFSHPADFTPVCTTEFIAFAKK
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHH
HDAFAARGAELLGLSIDSHYSHIAWMLNIKEKFGVEIRFPIIADLSMTVARAYGMIQPGA
HHHHHHCCCEEEEEEECCCCCEEEEEEEEHHHHCCEEEECEEECHHHHHHHHHCCCCCCC
SDTSAVRATFLIDPEGKLRAMVYYPMIAGRSVDEIYRLLVALQTADANKCAMPESWQPGD
CCCCEEEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
AVIVPPPATAAAALARAGEGYDTVDWYYSTRAL
EEEECCCCHHHHHHHHCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]