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The map label for this gene is blh [H]

Identifier: 86751697

GI number: 86751697

Start: 5193505

End: 5194377

Strand: Reverse

Name: blh [H]

Synonym: RPB_4599

Alternate gene names: 86751697

Gene position: 5194377-5193505 (Counterclockwise)

Preceding gene: 86751698

Following gene: 86751696

Centisome position: 97.43

GC content: 64.6

Gene sequence:

>873_bases
ATGACCAAGCCGATCGTGAAGCCGTTCTGGGACGAGGCGACTGGAAGCTGGCAATACGTATTTCATGATCCGCAGACGAT
GCGGGGCGCGGTGGTCGATCCGGTGTGGAACTACGACCCGAAAGCCGGTGCCACATTCACCCGCAGTGTCGACGAGATCG
TCGCCTATGTGCGGGAGGCCGGAATCGACGTCGTCTGGATCCTCGACACGCATCCGCATGCCGATCATTTCTCGGCGGCG
CCGCTCCTGTCCGAACGGCTGAAGGCGCCGACCGGGATCGGCGAGCGCGTCACCGAGGTGCAGAAGCTGTGGCAGAAGAT
CTATCATCTGCCGGAGTCGTTTCCGACCGACGGCCGCCAATGGGACCGGCTGTTCGCCGACGGCGACATCTTCATGGTCG
GCGACATTCCGGTGCGGGTGATGTTTTCGCCTGGACACACATTGGCGTCGGTCACCTATGTGGCCGGCGATGCCGCCTTC
GTCCATGATACGCTGATGATGCCGGACAGCGGCACCAGCCGCGCCGATTTTCCCGGCGGCTCGTCGAAGCAGCTGTATGC
CAGCCTGCAGCGGATCCTGTCGCTCCCCGACGACACCCGGCTTTACGTCGGCCACGACTATGCGCCCGAGGGGCGCGACG
CGCAGTGCATGGCGACGGTCGCCGAACACAAGGCGCGCAACATCCATCTTGCCGGCGGTCGCAGCGAAGCCGAGTTCTGC
GCCGCCCGCGACCGGCGCGACGCGTCTCTGCCGCTGCCGAAACTGATGCTCGCAGCGCTGCAAATCAACATCCGCGGCGG
CCGCAAGCCGGAGCCGGAAGCCGACGGGCGCTCTTATTTGAAGATTCCGCTGGACTATTTCGAGCCGCGTTGA

Upstream 100 bases:

>100_bases
GAAGCAGCTCTGGATGATGAAGGCAGCCCGCGCCTGACGATTGCTGCGGCGTCTTCCGAAGGGGGCGCCGCGGTTTACCG
ATGCAGAGGAGGACCGACCG

Downstream 100 bases:

>100_bases
TCGCCCGGATTGCGGAAGGCGCCGGTCGTTGCATCGGCGTCTTCCGGGCCGCGGCGCGGCTCCCCGGCGGTCGCCGATCC
GGATTCCGATCCGCTCCGTC

Product: Beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTKPIVKPFWDEATGSWQYVFHDPQTMRGAVVDPVWNYDPKAGATFTRSVDEIVAYVREAGIDVVWILDTHPHADHFSAA
PLLSERLKAPTGIGERVTEVQKLWQKIYHLPESFPTDGRQWDRLFADGDIFMVGDIPVRVMFSPGHTLASVTYVAGDAAF
VHDTLMMPDSGTSRADFPGGSSKQLYASLQRILSLPDDTRLYVGHDYAPEGRDAQCMATVAEHKARNIHLAGGRSEAEFC
AARDRRDASLPLPKLMLAALQINIRGGRKPEPEADGRSYLKIPLDYFEPR

Sequences:

>Translated_290_residues
MTKPIVKPFWDEATGSWQYVFHDPQTMRGAVVDPVWNYDPKAGATFTRSVDEIVAYVREAGIDVVWILDTHPHADHFSAA
PLLSERLKAPTGIGERVTEVQKLWQKIYHLPESFPTDGRQWDRLFADGDIFMVGDIPVRVMFSPGHTLASVTYVAGDAAF
VHDTLMMPDSGTSRADFPGGSSKQLYASLQRILSLPDDTRLYVGHDYAPEGRDAQCMATVAEHKARNIHLAGGRSEAEFC
AARDRRDASLPLPKLMLAALQINIRGGRKPEPEADGRSYLKIPLDYFEPR
>Mature_289_residues
TKPIVKPFWDEATGSWQYVFHDPQTMRGAVVDPVWNYDPKAGATFTRSVDEIVAYVREAGIDVVWILDTHPHADHFSAAP
LLSERLKAPTGIGERVTEVQKLWQKIYHLPESFPTDGRQWDRLFADGDIFMVGDIPVRVMFSPGHTLASVTYVAGDAAFV
HDTLMMPDSGTSRADFPGGSSKQLYASLQRILSLPDDTRLYVGHDYAPEGRDAQCMATVAEHKARNIHLAGGRSEAEFCA
ARDRRDASLPLPKLMLAALQINIRGGRKPEPEADGRSYLKIPLDYFEPR

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=266, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1787158, Length=186, Percent_Identity=28.494623655914, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538952, Length=268, Percent_Identity=25.3731343283582, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221330176, Length=264, Percent_Identity=25, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32351; Mature: 32220

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVKPFWDEATGSWQYVFHDPQTMRGAVVDPVWNYDPKAGATFTRSVDEIVAYVREA
CCCCCCCCCCCCCCCCEEEEEECCCHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GIDVVWILDTHPHADHFSAAPLLSERLKAPTGIGERVTEVQKLWQKIYHLPESFPTDGRQ
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
WDRLFADGDIFMVGDIPVRVMFSPGHTLASVTYVAGDAAFVHDTLMMPDSGTSRADFPGG
HHHEECCCCEEEECCCCEEEEECCCCCEEEEEEECCCHHHHHHEEECCCCCCCCCCCCCC
SSKQLYASLQRILSLPDDTRLYVGHDYAPEGRDAQCMATVAEHKARNIHLAGGRSEAEFC
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHH
AARDRRDASLPLPKLMLAALQINIRGGRKPEPEADGRSYLKIPLDYFEPR
HHCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEEHHHCCCC
>Mature Secondary Structure 
TKPIVKPFWDEATGSWQYVFHDPQTMRGAVVDPVWNYDPKAGATFTRSVDEIVAYVREA
CCCCCCCCCCCCCCCEEEEEECCCHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
GIDVVWILDTHPHADHFSAAPLLSERLKAPTGIGERVTEVQKLWQKIYHLPESFPTDGRQ
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHH
WDRLFADGDIFMVGDIPVRVMFSPGHTLASVTYVAGDAAFVHDTLMMPDSGTSRADFPGG
HHHEECCCCEEEECCCCEEEEECCCCCEEEEEEECCCHHHHHHEEECCCCCCCCCCCCCC
SSKQLYASLQRILSLPDDTRLYVGHDYAPEGRDAQCMATVAEHKARNIHLAGGRSEAEFC
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHH
AARDRRDASLPLPKLMLAALQINIRGGRKPEPEADGRSYLKIPLDYFEPR
HHCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]