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The map label for this gene is yjiA [H]

Identifier: 86751654

GI number: 86751654

Start: 5150083

End: 5151126

Strand: Reverse

Name: yjiA [H]

Synonym: RPB_4556

Alternate gene names: 86751654

Gene position: 5151126-5150083 (Counterclockwise)

Preceding gene: 86751655

Following gene: 86751653

Centisome position: 96.61

GC content: 62.36

Gene sequence:

>1044_bases
ATGACGAACTCCGCCGCCTCGAAAATTCCCGTCACCGTGCTCACCGGCTATCTCGGCGCCGGCAAGACGACGCTGCTCAA
CCGCATCCTGTCGGAGAATCACGGCAAGAAATACGCGGTGATCGTCAACGAGTTCGGCGAGATCGGCATCGACAACGACC
TGATCATCGGTGCCGACGAGGAAGTGTTCGAGATGAACAATGGCTGCGTCTGCTGCACGGTGCGCGGCGACCTGGTCCGG
ATTCTCGGCGGGCTGATGAAGCGCAAGGGCAAGTTCGACGCCATCATCGTCGAGACCACCGGGCTCGCCGATCCGGCGCC
GGTGGCGCAGACCTTCTTCGTCGACGAGGACGTGATGGCGAGCGCACGGCTCGACGCGGTGGTGACGGTGGCCGACGCCA
AATGGCTGAGCGACCGCCTCAAGGATGCGCCCGAGGCCAAGAACCAGATCGCCTTCGCGGACGTCATCGTGCTCAACAAG
ACCGACCTCGTCACCAAGGCCGAACTCGCCGAAGTCGAGGCGCGGATCCGCGCGATCAATCCCTATGCCCGGCTGCATCA
CACCGAACGCTGCCAGATCCCGATCGCCGACGTACTCGATCGCGGCGCGTTCGATCTCGACCGCATTCTGGAGATCGAGC
CGGAGTTTCTCGATGCCGGCGACGATCACGATCACCACCATGATCACGATCATGGTCATCATCATCACGACCACCACGGC
CACGGCCTGAAGCACTATCACGATGAGGACATGCAATCGCTGTCGCTGAAGAGCGACAAGCCGATCGACCCGGCGAAGTT
CATGCCCTGGCTGCAGCAATTGGTGCAGACCGAAGGCGGAAAGATCCTGCGCTCCAAGGGGATTCTGTCTTTTGCGGGTG
ACGACGACCGCTACGTGTTTCAGGGCGTGCACATGATGCTCGAGGGCGATCACCAGCGCGCCTGGAAGGACGACGAGCCG
CGCGAAAGCCGCGTCGTGTTCATCGGTCGCGAATTGCCCGAACAGGCGATCCGCGACGGCTTCGCGAAGTGCGTGGCGCA
ATGA

Upstream 100 bases:

>100_bases
GCGTCTCGCTGGATGAAAACAACGCCTTCACTCTCATCCTTCGAGATGCGCGCAGTCGTGCGCTCCTCAGGGTGAGAGCT
CGTTCTGGAGCACCTGCCTG

Downstream 100 bases:

>100_bases
GCGACTTCGAAACGTCCGGCGAGGCGGCCTCGATCGTCTCGGTCACCGACCGCGTCCGCGAGGTCGCGATCGGCGCGCCG
GTGGGGGCGGTGCATTTCCT

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTNSAASKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIIGADEEVFEMNNGCVCCTVRGDLVR
ILGGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVMASARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVIVLNK
TDLVTKAELAEVEARIRAINPYARLHHTERCQIPIADVLDRGAFDLDRILEIEPEFLDAGDDHDHHHDHDHGHHHHDHHG
HGLKHYHDEDMQSLSLKSDKPIDPAKFMPWLQQLVQTEGGKILRSKGILSFAGDDDRYVFQGVHMMLEGDHQRAWKDDEP
RESRVVFIGRELPEQAIRDGFAKCVAQ

Sequences:

>Translated_347_residues
MTNSAASKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIIGADEEVFEMNNGCVCCTVRGDLVR
ILGGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVMASARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVIVLNK
TDLVTKAELAEVEARIRAINPYARLHHTERCQIPIADVLDRGAFDLDRILEIEPEFLDAGDDHDHHHDHDHGHHHHDHHG
HGLKHYHDEDMQSLSLKSDKPIDPAKFMPWLQQLVQTEGGKILRSKGILSFAGDDDRYVFQGVHMMLEGDHQRAWKDDEP
RESRVVFIGRELPEQAIRDGFAKCVAQ
>Mature_346_residues
TNSAASKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIIGADEEVFEMNNGCVCCTVRGDLVRI
LGGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVMASARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVIVLNKT
DLVTKAELAEVEARIRAINPYARLHHTERCQIPIADVLDRGAFDLDRILEIEPEFLDAGDDHDHHHDHDHGHHHHDHHGH
GLKHYHDEDMQSLSLKSDKPIDPAKFMPWLQQLVQTEGGKILRSKGILSFAGDDDRYVFQGVHMMLEGDHQRAWKDDEPR
ESRVVFIGRELPEQAIRDGFAKCVAQ

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=362, Percent_Identity=33.4254143646409, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI126722884, Length=362, Percent_Identity=33.1491712707182, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI148727351, Length=362, Percent_Identity=33.1491712707182, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI146231952, Length=362, Percent_Identity=32.8729281767956, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI223941779, Length=354, Percent_Identity=33.0508474576271, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI223941776, Length=363, Percent_Identity=32.2314049586777, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI119120938, Length=135, Percent_Identity=48.8888888888889, Blast_Score=138, Evalue=7e-33,
Organism=Escherichia coli, GI87082430, Length=342, Percent_Identity=35.0877192982456, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1788499, Length=165, Percent_Identity=34.5454545454545, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324356, Length=383, Percent_Identity=28.9817232375979, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38680; Mature: 38549

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSAASKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIIGADE
CCCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECCCH
EVFEMNNGCVCCTVRGDLVRILGGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVMA
HHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHEEECCHHHHH
SARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVIVLNKTDLVTKAELAEVEARIRAIN
HHHHCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
PYARLHHTERCQIPIADVLDRGAFDLDRILEIEPEFLDAGDDHDHHHDHDHGHHHHDHHG
HHHHHCCCCCCCCCHHHHHCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
HGLKHYHDEDMQSLSLKSDKPIDPAKFMPWLQQLVQTEGGKILRSKGILSFAGDDDRYVF
CCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHH
QGVHMMLEGDHQRAWKDDEPRESRVVFIGRELPEQAIRDGFAKCVAQ
HHHHHEEECCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNSAASKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEIGIDNDLIIGADE
CCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEECCCH
EVFEMNNGCVCCTVRGDLVRILGGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVMA
HHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHEEECCHHHHH
SARLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVIVLNKTDLVTKAELAEVEARIRAIN
HHHHCEEEEEHHHHHHHHHHHCCCCHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
PYARLHHTERCQIPIADVLDRGAFDLDRILEIEPEFLDAGDDHDHHHDHDHGHHHHDHHG
HHHHHCCCCCCCCCHHHHHCCCCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
HGLKHYHDEDMQSLSLKSDKPIDPAKFMPWLQQLVQTEGGKILRSKGILSFAGDDDRYVF
CCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHH
QGVHMMLEGDHQRAWKDDEPRESRVVFIGRELPEQAIRDGFAKCVAQ
HHHHHEEECCHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]