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The map label for this gene is yafC [C]

Identifier: 86751602

GI number: 86751602

Start: 5091660

End: 5092574

Strand: Reverse

Name: yafC [C]

Synonym: RPB_4504

Alternate gene names: 86751602

Gene position: 5092574-5091660 (Counterclockwise)

Preceding gene: 86751605

Following gene: 86751600

Centisome position: 95.52

GC content: 71.26

Gene sequence:

>915_bases
ATGACCAAGCTGCCGGATTTCGAAGCGCTGGCGATCTTCGCCAAGGTCGTCGAGTTGCGATCCTTTGCGGCCACCGCGGC
CGAGCTGGCGCTGTCCAAGGCGACGGTGTCGAAGGCGGTGACGCGGCTCGAGGCGCGGCTCGGCGCCCGGCTGTTCAATC
GGACGTCGCGGCGGCTGGCGCTCACCGACGCCGGCCAGCGGCTGGCCGAGCGCGCCGCGCAATTGCTCGCCGACGGCGAG
GCGGCGGAAAGCGAGGCGCTGGCGCAGTCGGCCGCGCCGCGCGGCCTGGTGCGGCTGGCGGTGCCGATGACCTTCGGCGT
CAAGGTGATCGCGCCGCTGCTGCCGGACTTCCTCGCCGCCTATCCCGAGGTCTCGATCGACCTGCATCTGTCGGATGCGA
TGGTCGATCTGATCGGCGAGGGCTTCGACGCAGGCGTGCGGATCGCCTCATTGCCGGATTCGTCGCTGGTGGCGCGGCGG
CTGTGCGCGATGCCGCGCTACACGGTGGCATCGAAGGCCTATCTGGCGCAGCACGGCCGCCCGACGCATCCGATGCATCT
CGCCGCGCATCGCTGCTTCGGCTACGCCTATTTGTCGACGCCGAATGTCTGGACCTACACCAATGCGGAAGGCGAACAGG
CGTCGGTGCGGCCGTCCGGCCCGCTCCGTGTCAACAATGGCGAGGCGGTGCTGCCGGCGGTGATCGCGGGGCTCGGCATC
GCCGATCTGCCGGAGTTCATCGTCGGCGACGCCATCGCTGCCGGCGCGGTCGAGGTGATCCTGCAGGGCTGGCACCAGCG
CGAAGGCTCGGTGCATCTGGTGATGCCGCCCGGCGGCCCCCGGCCGGCGCGGGTCGAGGTGCTGGCGGCGTTCCTGGCCG
ACCGGCTGGGGCCGAAGCGCCGCCTCCCGAGCTGA

Upstream 100 bases:

>100_bases
GGTGAGGTGTTGGGTATTGGAATAGTGGCTCGCTTGCATTTCAGAAATAGAAATGATTGAAACTAATTGTTTCCAATAAC
GTCCTAATGCGAGCTGAGGC

Downstream 100 bases:

>100_bases
GCGCGCGCGTGCTGGCGCGACGCGCTCAGTTCAGATTGACGTTGAACTCGTAGGATTTCTCCGGCCCGACCAGGGTGAAT
TTCAGCGCCGCGCCTTCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTKLPDFEALAIFAKVVELRSFAATAAELALSKATVSKAVTRLEARLGARLFNRTSRRLALTDAGQRLAERAAQLLADGE
AAESEALAQSAAPRGLVRLAVPMTFGVKVIAPLLPDFLAAYPEVSIDLHLSDAMVDLIGEGFDAGVRIASLPDSSLVARR
LCAMPRYTVASKAYLAQHGRPTHPMHLAAHRCFGYAYLSTPNVWTYTNAEGEQASVRPSGPLRVNNGEAVLPAVIAGLGI
ADLPEFIVGDAIAAGAVEVILQGWHQREGSVHLVMPPGGPRPARVEVLAAFLADRLGPKRRLPS

Sequences:

>Translated_304_residues
MTKLPDFEALAIFAKVVELRSFAATAAELALSKATVSKAVTRLEARLGARLFNRTSRRLALTDAGQRLAERAAQLLADGE
AAESEALAQSAAPRGLVRLAVPMTFGVKVIAPLLPDFLAAYPEVSIDLHLSDAMVDLIGEGFDAGVRIASLPDSSLVARR
LCAMPRYTVASKAYLAQHGRPTHPMHLAAHRCFGYAYLSTPNVWTYTNAEGEQASVRPSGPLRVNNGEAVLPAVIAGLGI
ADLPEFIVGDAIAAGAVEVILQGWHQREGSVHLVMPPGGPRPARVEVLAAFLADRLGPKRRLPS
>Mature_303_residues
TKLPDFEALAIFAKVVELRSFAATAAELALSKATVSKAVTRLEARLGARLFNRTSRRLALTDAGQRLAERAAQLLADGEA
AESEALAQSAAPRGLVRLAVPMTFGVKVIAPLLPDFLAAYPEVSIDLHLSDAMVDLIGEGFDAGVRIASLPDSSLVARRL
CAMPRYTVASKAYLAQHGRPTHPMHLAAHRCFGYAYLSTPNVWTYTNAEGEQASVRPSGPLRVNNGEAVLPAVIAGLGIA
DLPEFIVGDAIAAGAVEVILQGWHQREGSVHLVMPPGGPRPARVEVLAAFLADRLGPKRRLPS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=248, Percent_Identity=35.8870967741936, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=31.5789473684211, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=267, Percent_Identity=35.2059925093633, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=31.8791946308725, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787128, Length=281, Percent_Identity=28.4697508896797, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789440, Length=303, Percent_Identity=29.7029702970297, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787589, Length=278, Percent_Identity=30.2158273381295, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI157672245, Length=237, Percent_Identity=29.535864978903, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789173, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788481, Length=139, Percent_Identity=31.6546762589928, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32306; Mature: 32175

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLPDFEALAIFAKVVELRSFAATAAELALSKATVSKAVTRLEARLGARLFNRTSRRLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGQRLAERAAQLLADGEAAESEALAQSAAPRGLVRLAVPMTFGVKVIAPLLPDFLAA
EHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
YPEVSIDLHLSDAMVDLIGEGFDAGVRIASLPDSSLVARRLCAMPRYTVASKAYLAQHGR
CCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
PTHPMHLAAHRCFGYAYLSTPNVWTYTNAEGEQASVRPSGPLRVNNGEAVLPAVIAGLGI
CCCHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCH
ADLPEFIVGDAIAAGAVEVILQGWHQREGSVHLVMPPGGPRPARVEVLAAFLADRLGPKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
RLPS
CCCC
>Mature Secondary Structure 
TKLPDFEALAIFAKVVELRSFAATAAELALSKATVSKAVTRLEARLGARLFNRTSRRLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LTDAGQRLAERAAQLLADGEAAESEALAQSAAPRGLVRLAVPMTFGVKVIAPLLPDFLAA
EHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
YPEVSIDLHLSDAMVDLIGEGFDAGVRIASLPDSSLVARRLCAMPRYTVASKAYLAQHGR
CCCCEEEEEHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCC
PTHPMHLAAHRCFGYAYLSTPNVWTYTNAEGEQASVRPSGPLRVNNGEAVLPAVIAGLGI
CCCHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCH
ADLPEFIVGDAIAAGAVEVILQGWHQREGSVHLVMPPGGPRPARVEVLAAFLADRLGPKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
RLPS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]