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The map label for this gene is dgdR [H]

Identifier: 86750937

GI number: 86750937

Start: 4372180

End: 4373049

Strand: Reverse

Name: dgdR [H]

Synonym: RPB_3829

Alternate gene names: 86750937

Gene position: 4373049-4372180 (Counterclockwise)

Preceding gene: 86750940

Following gene: 86750934

Centisome position: 82.02

GC content: 71.26

Gene sequence:

>870_bases
ATGGTTATCCGGATGCCGCGCCCGCTGCTCAATCTCGATCTCGACCTGGTCCGGGCATTCGTCGCCATCGCCACGCTGGG
CAATTTCACCCGCGCGGCGGAGTCGCTGCGGCGCCAGCAATCGACCGTGTCGCTGCAGTTGCAGCGGCTGGAAGACGCGC
TCGGCCGCAAGCTGCTGGAGCGCAATCCGCGCAGTGTCCGGCTGACGCCCGAGGGCGAGGTGTTTCTCGCCCATGCGCGC
CGGCTGCTCGACGTCAACGACGAACTGGTCGCCCGCGTCACCGAGCCGGCGCTGCACGGCGCGGTGCGGCTCGGCACGCC
CGAGGATTTCGCGACGCGGCATCTGCCCGAGGTGCTGTCGCGCTTCGCCCGGGCCTATCCGGCGGTGGCGCTGGAAGTGA
CCTGCGATCTGACGCTGCATGTCATCGACGGCTTCAGGAAAGGCAGCTTCGATCTGGCGCTGATCAAGCGCGAGCGGGTC
GGCGAGGCCGCCGGCATCCGGGTGTGGCGCGAGCCGCTGGTGTGGGTCGCCGGCGAGGCGGCGCCGCAGCAGCGCGACGG
GCCGCTGCCGCTGGTGGTGTCGCCGAGCCCCTGCGTCTACCGTAAGCGCGCCACCGAGGCCCTCGATAAGGCGCGGCGGC
CGTGGCGGATCGCCTATACCTGCGGCTCGCTCGCCGGCTCGCTGGCGGCGGTGCGCGGCGGGCTCGGCGTCACGGTGCTG
CCGAAGGACATGGTGCCGGAGGATCTGCACGTGATCGACGGAGGCCCGCTGCCGAGCCTCAGGGACACCGAGATCGCGTT
GCTGCAGCGCGAGCGATTGTCCCTGCCGGCGCAGCGGCTGAAGGAGCACATCGTGCGCTCGCTGGGGTGA

Upstream 100 bases:

>100_bases
GCGGCGGCGTGAGGCCCGCGGCAGCGGGCGGGGCGGAACCTAGGTGCGGTTGCAGCATCTTGGAAATTGATTATAGAAAC
TTCTATCATTGCATTTTACA

Downstream 100 bases:

>100_bases
GTCATGCGCGAATGAGCTGCTTCCCGGCGGGCCGACTTGTGAGTATCAGCCCTTGCGCAGCGCGAAATGCGCTCCGCAGA
ACGCCATCACGGCGCCGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MVIRMPRPLLNLDLDLVRAFVAIATLGNFTRAAESLRRQQSTVSLQLQRLEDALGRKLLERNPRSVRLTPEGEVFLAHAR
RLLDVNDELVARVTEPALHGAVRLGTPEDFATRHLPEVLSRFARAYPAVALEVTCDLTLHVIDGFRKGSFDLALIKRERV
GEAAGIRVWREPLVWVAGEAAPQQRDGPLPLVVSPSPCVYRKRATEALDKARRPWRIAYTCGSLAGSLAAVRGGLGVTVL
PKDMVPEDLHVIDGGPLPSLRDTEIALLQRERLSLPAQRLKEHIVRSLG

Sequences:

>Translated_289_residues
MVIRMPRPLLNLDLDLVRAFVAIATLGNFTRAAESLRRQQSTVSLQLQRLEDALGRKLLERNPRSVRLTPEGEVFLAHAR
RLLDVNDELVARVTEPALHGAVRLGTPEDFATRHLPEVLSRFARAYPAVALEVTCDLTLHVIDGFRKGSFDLALIKRERV
GEAAGIRVWREPLVWVAGEAAPQQRDGPLPLVVSPSPCVYRKRATEALDKARRPWRIAYTCGSLAGSLAAVRGGLGVTVL
PKDMVPEDLHVIDGGPLPSLRDTEIALLQRERLSLPAQRLKEHIVRSLG
>Mature_289_residues
MVIRMPRPLLNLDLDLVRAFVAIATLGNFTRAAESLRRQQSTVSLQLQRLEDALGRKLLERNPRSVRLTPEGEVFLAHAR
RLLDVNDELVARVTEPALHGAVRLGTPEDFATRHLPEVLSRFARAYPAVALEVTCDLTLHVIDGFRKGSFDLALIKRERV
GEAAGIRVWREPLVWVAGEAAPQQRDGPLPLVVSPSPCVYRKRATEALDKARRPWRIAYTCGSLAGSLAAVRGGLGVTVL
PKDMVPEDLHVIDGGPLPSLRDTEIALLQRERLSLPAQRLKEHIVRSLG

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=267, Percent_Identity=36.3295880149813, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1787806, Length=253, Percent_Identity=27.6679841897233, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=31.0483870967742, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=258, Percent_Identity=24.031007751938, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=30.5882352941176, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=260, Percent_Identity=28.0769230769231, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693193, Length=133, Percent_Identity=33.8345864661654, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789639, Length=128, Percent_Identity=29.6875, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI157672245, Length=125, Percent_Identity=32, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=120, Percent_Identity=35, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081904, Length=140, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786448, Length=145, Percent_Identity=31.7241379310345, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788297, Length=236, Percent_Identity=26.271186440678, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI2367136, Length=119, Percent_Identity=34.453781512605, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31998; Mature: 31998

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRMPRPLLNLDLDLVRAFVAIATLGNFTRAAESLRRQQSTVSLQLQRLEDALGRKLLE
CEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNPRSVRLTPEGEVFLAHARRLLDVNDELVARVTEPALHGAVRLGTPEDFATRHLPEVLS
CCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHH
RFARAYPAVALEVTCDLTLHVIDGFRKGSFDLALIKRERVGEAAGIRVWREPLVWVAGEA
HHHHHCCCEEEEEEECEEEEEHHCCCCCCCEEEEEEHHHCCCHHHHHHHHCCEEEEECCC
APQQRDGPLPLVVSPSPCVYRKRATEALDKARRPWRIAYTCGSLAGSLAAVRGGLGVTVL
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCEEEC
PKDMVPEDLHVIDGGPLPSLRDTEIALLQRERLSLPAQRLKEHIVRSLG
CCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVIRMPRPLLNLDLDLVRAFVAIATLGNFTRAAESLRRQQSTVSLQLQRLEDALGRKLLE
CEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNPRSVRLTPEGEVFLAHARRLLDVNDELVARVTEPALHGAVRLGTPEDFATRHLPEVLS
CCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHH
RFARAYPAVALEVTCDLTLHVIDGFRKGSFDLALIKRERVGEAAGIRVWREPLVWVAGEA
HHHHHCCCEEEEEEECEEEEEHHCCCCCCCEEEEEEHHHCCCHHHHHHHHCCEEEEECCC
APQQRDGPLPLVVSPSPCVYRKRATEALDKARRPWRIAYTCGSLAGSLAAVRGGLGVTVL
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCEEEC
PKDMVPEDLHVIDGGPLPSLRDTEIALLQRERLSLPAQRLKEHIVRSLG
CCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]