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The map label for this gene is msrB [H]

Identifier: 86750930

GI number: 86750930

Start: 4367002

End: 4367499

Strand: Reverse

Name: msrB [H]

Synonym: RPB_3821

Alternate gene names: 86750930

Gene position: 4367499-4367002 (Counterclockwise)

Preceding gene: 86750931

Following gene: 86750929

Centisome position: 81.92

GC content: 67.47

Gene sequence:

>498_bases
ATGATCGACCGCCGCATCCTGCTCGCTTCCGCCGCGCTCGCGGCGGTGTTCGGATTCCGCTGGCTGCGGCCCGACGACGC
CCGCGCCGCGGAAAAATTCGAGATCGAAAAGACGCCGGAGGAATGGCGCAAGCAGCTCACGCCGATGCAGTACCACATCC
TGCGCGAGGAAGGCACCGAGCGGCCGTTCTCCAGCCCGCTGCTGAAGGAACACCGCAAGGGCACCTTCGCCTGCGCCGGC
TGCGACCTGCCGCTGTTTTCGTCCGAGACCAAATACGACAGCGGCACCGGCTGGCCGAGCTTCTGGCAGCCGCTGCCGAA
CGCGGTCGGCGAGCGCAAGGACTCGACGCTCGGCATGGTGCGCACCGAAATCCACTGCCGCCGCTGCGGAGGCCATCTCG
GCCATGTGTTCGACGACGGCCCGAAGCCGACCGGCCTGCGCTACTGCATGGACGGCTTCGCACTGACCTTCAAGCCGGAG
ACGTCGAAGCCGAGCTGA

Upstream 100 bases:

>100_bases
CCGGCAGGGCGCTGATGTAACTTTGAGGGTGCCGCCTGCGTATCTCGGACCAAGGCCACACAATCCGATCCGCCCCGCCC
GCGCACCGCACGGAGACACC

Downstream 100 bases:

>100_bases
CGGGCTCCCTGGGGCGGTTCGTCGCGGAACGGGCCGCCCCGAAGCATTTTGCTTGTCGCTACGTCTCAATTCGAGGTTTT
CAAGCCGCGAAAGCCTCCGG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MIDRRILLASAALAAVFGFRWLRPDDARAAEKFEIEKTPEEWRKQLTPMQYHILREEGTERPFSSPLLKEHRKGTFACAG
CDLPLFSSETKYDSGTGWPSFWQPLPNAVGERKDSTLGMVRTEIHCRRCGGHLGHVFDDGPKPTGLRYCMDGFALTFKPE
TSKPS

Sequences:

>Translated_165_residues
MIDRRILLASAALAAVFGFRWLRPDDARAAEKFEIEKTPEEWRKQLTPMQYHILREEGTERPFSSPLLKEHRKGTFACAG
CDLPLFSSETKYDSGTGWPSFWQPLPNAVGERKDSTLGMVRTEIHCRRCGGHLGHVFDDGPKPTGLRYCMDGFALTFKPE
TSKPS
>Mature_165_residues
MIDRRILLASAALAAVFGFRWLRPDDARAAEKFEIEKTPEEWRKQLTPMQYHILREEGTERPFSSPLLKEHRKGTFACAG
CDLPLFSSETKYDSGTGWPSFWQPLPNAVGERKDSTLGMVRTEIHCRRCGGHLGHVFDDGPKPTGLRYCMDGFALTFKPE
TSKPS

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=136, Percent_Identity=45.5882352941176, Blast_Score=134, Evalue=4e-32,
Organism=Homo sapiens, GI301336162, Length=136, Percent_Identity=45.5882352941176, Blast_Score=134, Evalue=4e-32,
Organism=Homo sapiens, GI73089054, Length=136, Percent_Identity=45.5882352941176, Blast_Score=134, Evalue=4e-32,
Organism=Homo sapiens, GI37620216, Length=136, Percent_Identity=45.5882352941176, Blast_Score=133, Evalue=7e-32,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=47.7611940298507, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=49.5867768595041, Blast_Score=129, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=137, Percent_Identity=37.2262773722628, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI115532676, Length=135, Percent_Identity=37.7777777777778, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6319816, Length=138, Percent_Identity=39.1304347826087, Blast_Score=111, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645799, Length=140, Percent_Identity=47.8571428571429, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI221378664, Length=130, Percent_Identity=49.2307692307692, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI221378662, Length=137, Percent_Identity=48.1751824817518, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI45553335, Length=140, Percent_Identity=47.8571428571429, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356369, Length=140, Percent_Identity=47.8571428571429, Blast_Score=132, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24645801, Length=151, Percent_Identity=44.3708609271523, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645804, Length=151, Percent_Identity=44.3708609271523, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18688; Mature: 18688

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRILLASAALAAVFGFRWLRPDDARAAEKFEIEKTPEEWRKQLTPMQYHILREEGTE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHCCCC
RPFSSPLLKEHRKGTFACAGCDLPLFSSETKYDSGTGWPSFWQPLPNAVGERKDSTLGMV
CCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
RTEIHCRRCGGHLGHVFDDGPKPTGLRYCMDGFALTFKPETSKPS
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCC
>Mature Secondary Structure
MIDRRILLASAALAAVFGFRWLRPDDARAAEKFEIEKTPEEWRKQLTPMQYHILREEGTE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHCCCHHHHHHHHCCCC
RPFSSPLLKEHRKGTFACAGCDLPLFSSETKYDSGTGWPSFWQPLPNAVGERKDSTLGMV
CCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHH
RTEIHCRRCGGHLGHVFDDGPKPTGLRYCMDGFALTFKPETSKPS
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]