Click here to switch to the map view.

The map label for this gene is yogA [H]

Identifier: 86750468

GI number: 86750468

Start: 3838780

End: 3839802

Strand: Direct

Name: yogA [H]

Synonym: RPB_3357

Alternate gene names: 86750468

Gene position: 3838780-3839802 (Clockwise)

Preceding gene: 86750467

Following gene: 86750469

Centisome position: 72.0

GC content: 65.3

Gene sequence:

>1023_bases
ATGCGCGCGCTCACTCTCGTTGCCGACCGCGATCTCGCGGTCTCCGATCTGCCGCCGCCGCCGCCGCCCGCGGCCGGCGA
GGTGCAGATCCGCGTCGCCGCGGTCGCGCTCAACCACATCGACGTCTGGGGCTATCGCGGCATGGCGTTCGTCAAGCGCA
AGCTGCCGATCGTGGTCGGCGCCGAAGCGTCGGGCACAATCGAGGCGGTCGGCGACGGCGTGACGCGCTTTGCGCCAGGC
CAGAAGGTCGTGATGTACGGCGCGCTGACCTGCGGTCACTGCAAGGCCTGCCTCGAAGGCCGCGATAATTTCTGTGAGAA
TGTCGGCGGACTGATCGGCTTCCACGTCGACGGATTCGCGCGTGAACTGATGAACATCCCGGCTCGGCTGGTGATCCCGG
TGCCGGACAGCGTGAGCCTGCGCGACGCCGCCTGCGCGCCGATCGCGTTCTCCACCGTGCAGCACATGCTGTTCGACAAC
GCCAAACTGCAGCCCGGCGAAACCATTCTGGTGCATGCCGGTGGCTCGGGCATCGGCACCGTCGCGATCATGATGGCCAA
GGCGATCGGCTGCACCGTGATCACCACGGTCGGCGACGACAGCAAGATCGAAGGCGTCAAGAAGCTCGGCGCGGACTACG
TGATCAACTACCGCAACCACCGCTTCGAGCACGAGACCCGAAAGATCACCAAGAAGAAGGGCGTTGACGTCGTGTTCGAA
CACGTCGGCGCCGACACCTTCAACGGCTCGCTGCTGGTGATGAAGCGCGGCGGCCGGCTCGTGACCTGCGGCTCGACCTC
GGGCCCGACCGCGACCATCAACCTGATGCAGCTGTTCCAGCAACAATACCGCATCTTCGGCTCGTTCGGCGCGACGATGA
AGAACATCGCCGAAAGCCTCGACAAGATGGCCGCGGGGATGCTGCCGGTGATCGACACCGAGGTGCCACTCGACGACGTC
GGCGCCGCACTGAAGCGGATGGAAAGCCGCCAGGTGTTCGGCAAGATCATCGTCCACTTCTGA

Upstream 100 bases:

>100_bases
ATGTCGAACTCGTTCGGGTTCGGCGGCCAGAACGCTTCCCTGATTCTGACGCGCGAGCCGGTCTAGCCGCGCCAGAACAC
AACTGTTTCGGACACGATAC

Downstream 100 bases:

>100_bases
TGAAACTACACCTGCTCCGCGCCAAGCTGCGTGCGCAACGCGCAGCCAAGACCGCCGCAGGCACTATCGCCGGCTCGGCG
GCGATCGGCGCGCTGCACCT

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRALTLVADRDLAVSDLPPPPPPAAGEVQIRVAAVALNHIDVWGYRGMAFVKRKLPIVVGAEASGTIEAVGDGVTRFAPG
QKVVMYGALTCGHCKACLEGRDNFCENVGGLIGFHVDGFARELMNIPARLVIPVPDSVSLRDAACAPIAFSTVQHMLFDN
AKLQPGETILVHAGGSGIGTVAIMMAKAIGCTVITTVGDDSKIEGVKKLGADYVINYRNHRFEHETRKITKKKGVDVVFE
HVGADTFNGSLLVMKRGGRLVTCGSTSGPTATINLMQLFQQQYRIFGSFGATMKNIAESLDKMAAGMLPVIDTEVPLDDV
GAALKRMESRQVFGKIIVHF

Sequences:

>Translated_340_residues
MRALTLVADRDLAVSDLPPPPPPAAGEVQIRVAAVALNHIDVWGYRGMAFVKRKLPIVVGAEASGTIEAVGDGVTRFAPG
QKVVMYGALTCGHCKACLEGRDNFCENVGGLIGFHVDGFARELMNIPARLVIPVPDSVSLRDAACAPIAFSTVQHMLFDN
AKLQPGETILVHAGGSGIGTVAIMMAKAIGCTVITTVGDDSKIEGVKKLGADYVINYRNHRFEHETRKITKKKGVDVVFE
HVGADTFNGSLLVMKRGGRLVTCGSTSGPTATINLMQLFQQQYRIFGSFGATMKNIAESLDKMAAGMLPVIDTEVPLDDV
GAALKRMESRQVFGKIIVHF
>Mature_340_residues
MRALTLVADRDLAVSDLPPPPPPAAGEVQIRVAAVALNHIDVWGYRGMAFVKRKLPIVVGAEASGTIEAVGDGVTRFAPG
QKVVMYGALTCGHCKACLEGRDNFCENVGGLIGFHVDGFARELMNIPARLVIPVPDSVSLRDAACAPIAFSTVQHMLFDN
AKLQPGETILVHAGGSGIGTVAIMMAKAIGCTVITTVGDDSKIEGVKKLGADYVINYRNHRFEHETRKITKKKGVDVVFE
HVGADTFNGSLLVMKRGGRLVTCGSTSGPTATINLMQLFQQQYRIFGSFGATMKNIAESLDKMAAGMLPVIDTEVPLDDV
GAALKRMESRQVFGKIIVHF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=341, Percent_Identity=26.099706744868, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI22538444, Length=341, Percent_Identity=26.099706744868, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI194239674, Length=310, Percent_Identity=25.1612903225806, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI13236495, Length=310, Percent_Identity=25.1612903225806, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI18379349, Length=338, Percent_Identity=24.2603550295858, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24308257, Length=348, Percent_Identity=25.5747126436782, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI34577061, Length=281, Percent_Identity=31.3167259786477, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4501929, Length=255, Percent_Identity=32.5490196078431, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41872631, Length=171, Percent_Identity=30.9941520467836, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI71565152, Length=262, Percent_Identity=29.7709923664122, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501933, Length=316, Percent_Identity=29.1139240506329, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI156627571, Length=325, Percent_Identity=26.4615384615385, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI71565154, Length=265, Percent_Identity=27.9245283018868, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI67078404, Length=316, Percent_Identity=24.6835443037975, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI226059159, Length=140, Percent_Identity=32.8571428571429, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI226059133, Length=140, Percent_Identity=32.8571428571429, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI226056130, Length=140, Percent_Identity=32.8571428571429, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI197927207, Length=174, Percent_Identity=28.1609195402299, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI67078406, Length=309, Percent_Identity=24.9190938511327, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI28557745, Length=252, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI262073058, Length=219, Percent_Identity=29.6803652968037, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI71743840, Length=219, Percent_Identity=29.6803652968037, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=29.0030211480363, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788073, Length=289, Percent_Identity=29.4117647058824, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790045, Length=353, Percent_Identity=28.6118980169972, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787863, Length=273, Percent_Identity=27.1062271062271, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081918, Length=320, Percent_Identity=24.6875, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786518, Length=323, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790718, Length=283, Percent_Identity=27.9151943462898, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI226510992, Length=292, Percent_Identity=26.7123287671233, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=326, Percent_Identity=23.9263803680982, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562584, Length=323, Percent_Identity=22.9102167182663, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=332, Percent_Identity=25.3012048192771, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=219, Percent_Identity=28.7671232876712, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=325, Percent_Identity=23.6923076923077, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=221, Percent_Identity=28.5067873303167, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=135, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=343, Percent_Identity=25.3644314868805, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=323, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=322, Percent_Identity=23.9130434782609, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=327, Percent_Identity=24.1590214067278, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=320, Percent_Identity=23.75, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=327, Percent_Identity=23.8532110091743, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=322, Percent_Identity=22.360248447205, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=345, Percent_Identity=24.9275362318841, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320033, Length=269, Percent_Identity=25.6505576208178, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221330659, Length=140, Percent_Identity=32.8571428571429, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19920632, Length=140, Percent_Identity=32.8571428571429, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24581345, Length=223, Percent_Identity=26.457399103139, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737895, Length=106, Percent_Identity=33.9622641509434, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221457811, Length=347, Percent_Identity=26.2247838616715, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45550770, Length=347, Percent_Identity=26.2247838616715, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36333; Mature: 36333

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALTLVADRDLAVSDLPPPPPPAAGEVQIRVAAVALNHIDVWGYRGMAFVKRKLPIVVG
CCEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEEEEEHEEECCCCCHHHHHHCCCEEEE
AEASGTIEAVGDGVTRFAPGQKVVMYGALTCGHCKACLEGRDNFCENVGGLIGFHVDGFA
CCCCCCCEECCCCHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHCCEEEEEHHHHH
RELMNIPARLVIPVPDSVSLRDAACAPIAFSTVQHMLFDNAKLQPGETILVHAGGSGIGT
HHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
VAIMMAKAIGCTVITTVGDDSKIEGVKKLGADYVINYRNHRFEHETRKITKKKGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHH
HVGADTFNGSLLVMKRGGRLVTCGSTSGPTATINLMQLFQQQYRIFGSFGATMKNIAESL
HCCCCCCCCEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKMAAGMLPVIDTEVPLDDVGAALKRMESRQVFGKIIVHF
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MRALTLVADRDLAVSDLPPPPPPAAGEVQIRVAAVALNHIDVWGYRGMAFVKRKLPIVVG
CCEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEEEEEHEEECCCCCHHHHHHCCCEEEE
AEASGTIEAVGDGVTRFAPGQKVVMYGALTCGHCKACLEGRDNFCENVGGLIGFHVDGFA
CCCCCCCEECCCCHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHCCEEEEEHHHHH
RELMNIPARLVIPVPDSVSLRDAACAPIAFSTVQHMLFDNAKLQPGETILVHAGGSGIGT
HHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHH
VAIMMAKAIGCTVITTVGDDSKIEGVKKLGADYVINYRNHRFEHETRKITKKKGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHH
HVGADTFNGSLLVMKRGGRLVTCGSTSGPTATINLMQLFQQQYRIFGSFGATMKNIAESL
HCCCCCCCCEEEEEECCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKMAAGMLPVIDTEVPLDDVGAALKRMESRQVFGKIIVHF
HHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]