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The map label for this gene is cobL [H]

Identifier: 86750293

GI number: 86750293

Start: 3639353

End: 3640576

Strand: Direct

Name: cobL [H]

Synonym: RPB_3182

Alternate gene names: 86750293

Gene position: 3639353-3640576 (Clockwise)

Preceding gene: 86750291

Following gene: 86750294

Centisome position: 68.26

GC content: 71.41

Gene sequence:

>1224_bases
ATGACCGCCACCGATGACACGCCGACGCCGTGGCTGTCCATCGTCGGAATCGGCGAGGATGGCGTCGCGGGCCTGTCGGA
CAAAGCACGCGCGCTACTGGCGAACGCCGATCTCGTGATCGGCGGCGAGCGGCACCTCGCGATGGTTGCCGCGCTCGGCA
GGCCGACCCTGCCCTGGCGGGTGCCGTTCGCCGTGTCGCTGCCGGACGTGCTGGCGCAGCGCGGCCGCAGTGTCGTCGTG
CTGTGCTCGGGCGATCCGTTCTGGCACGGCGCCGGCGCTGTGCTCGCCGATCACCTCGCGCCGAGCGAATGGACCGCCCT
GCCGGCGCCGTCGACGTTCTCCTGGGCGGCGGCAAGGCTCGGCTGGCGGCTGGAAGAGACGATCACGCTCGGCCTCCACG
CCCGCCCCATCACCATGCTGCGGCCGCATCTGCAGCCCGGTTCTCGGCTCATCGTGCTGGTGCGCGATGGTGCCGCGGTG
GCGCAGATCGCGGCCTATCTGACGGCGACGGGTTTTGGACCGTCCAGCCTCACCGTGCTCGAAGCGCTCGGCGGCCCGCG
CGAGCGCATTCTCCGCGCAGCAGCGGCGAACTATACACTCACCGACGTCGCAGCACCGGTCGCGATCGGCATCGACGTGG
TCGCGCAACCCGATTCCGCCATCATCCCACACGCAAGCGGCCTGCCGGACGAGCTGTTCCAGACCGACGGCCAACTCACC
AAGCGCGCGATCCGCGCGGTGACGCTGTCGAGCCTCGCCCCACGGGGCGGCGAATTGTTGTGGGATATCGGCGCCGGCTC
GGGCTCGATCGGCATCGAATGGTTGCTGGCGGCGCGCAGCAACCGCGCGATCGGAATCGAAGCGCGGCCCGATCGGCTGG
CTTGCGCCCGCGGCAATGCCGACGCACTCGGCGTGCCGCATTTCGATCTCCGCCTTGGGCAAGCGCCGGAAGCGCTCGCC
GACCTGCCGACTCCGGACGCGGTGTTCATCGGCGGCGGCGCCGGCAATCCGGGCGTGCTGGACGCGGTGTGGCAGGCGCT
TCCACCCGGCGGACGGCTGGTGGTCAATGCCGTGACGCTGGAAACCGAGGCGCTGCTGATCGCCTGTCACGGCCGCCACG
GCGGCGAGTTGCTGCGGCTCGGCGTCGAACGCGCCGCGCCGGTCGGCGGGCTCACCGCCTGGCGCGCCGCGATCCCGGTG
GTGCAATGGAGCGTCCGCAAATGA

Upstream 100 bases:

>100_bases
CTCGATGCGCGGCTCCGCGGCGATCGCCGTCGCGAGTCGCGTCGCATCGGCGGTGCCGCCGAGGATCAACAGGCGCAGGC
GCTGGGCGGGATGGAGCATC

Downstream 100 bases:

>100_bases
CGCGCATCGTGATCGGCATTGGATTTCGCGCCGCCGCCCCTCAGGCGTCGATCGCCGAAGTCATCGCCGCTGCGCGCGGC
GCCGCTATGCCCGCACAACC

Product: precorrin-6y C5,15-methyltransferase, subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTATDDTPTPWLSIVGIGEDGVAGLSDKARALLANADLVIGGERHLAMVAALGRPTLPWRVPFAVSLPDVLAQRGRSVVV
LCSGDPFWHGAGAVLADHLAPSEWTALPAPSTFSWAAARLGWRLEETITLGLHARPITMLRPHLQPGSRLIVLVRDGAAV
AQIAAYLTATGFGPSSLTVLEALGGPRERILRAAAANYTLTDVAAPVAIGIDVVAQPDSAIIPHASGLPDELFQTDGQLT
KRAIRAVTLSSLAPRGGELLWDIGAGSGSIGIEWLLAARSNRAIGIEARPDRLACARGNADALGVPHFDLRLGQAPEALA
DLPTPDAVFIGGGAGNPGVLDAVWQALPPGGRLVVNAVTLETEALLIACHGRHGGELLRLGVERAAPVGGLTAWRAAIPV
VQWSVRK

Sequences:

>Translated_407_residues
MTATDDTPTPWLSIVGIGEDGVAGLSDKARALLANADLVIGGERHLAMVAALGRPTLPWRVPFAVSLPDVLAQRGRSVVV
LCSGDPFWHGAGAVLADHLAPSEWTALPAPSTFSWAAARLGWRLEETITLGLHARPITMLRPHLQPGSRLIVLVRDGAAV
AQIAAYLTATGFGPSSLTVLEALGGPRERILRAAAANYTLTDVAAPVAIGIDVVAQPDSAIIPHASGLPDELFQTDGQLT
KRAIRAVTLSSLAPRGGELLWDIGAGSGSIGIEWLLAARSNRAIGIEARPDRLACARGNADALGVPHFDLRLGQAPEALA
DLPTPDAVFIGGGAGNPGVLDAVWQALPPGGRLVVNAVTLETEALLIACHGRHGGELLRLGVERAAPVGGLTAWRAAIPV
VQWSVRK
>Mature_406_residues
TATDDTPTPWLSIVGIGEDGVAGLSDKARALLANADLVIGGERHLAMVAALGRPTLPWRVPFAVSLPDVLAQRGRSVVVL
CSGDPFWHGAGAVLADHLAPSEWTALPAPSTFSWAAARLGWRLEETITLGLHARPITMLRPHLQPGSRLIVLVRDGAAVA
QIAAYLTATGFGPSSLTVLEALGGPRERILRAAAANYTLTDVAAPVAIGIDVVAQPDSAIIPHASGLPDELFQTDGQLTK
RAIRAVTLSSLAPRGGELLWDIGAGSGSIGIEWLLAARSNRAIGIEARPDRLACARGNADALGVPHFDLRLGQAPEALAD
LPTPDAVFIGGGAGNPGVLDAVWQALPPGGRLVVNAVTLETEALLIACHGRHGGELLRLGVERAAPVGGLTAWRAAIPVV
QWSVRK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42277; Mature: 42146

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATDDTPTPWLSIVGIGEDGVAGLSDKARALLANADLVIGGERHLAMVAALGRPTLPWR
CCCCCCCCCCEEEEEEECCCCCCCCCHHHHEEEECCCEEECCCHHEEEEECCCCCCCCEE
VPFAVSLPDVLAQRGRSVVVLCSGDPFWHGAGAVLADHLAPSEWTALPAPSTFSWAAARL
CCEEECCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
GWRLEETITLGLHARPITMLRPHLQPGSRLIVLVRDGAAVAQIAAYLTATGFGPSSLTVL
CCEEEHEEEEECCCCCHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHH
EALGGPRERILRAAAANYTLTDVAAPVAIGIDVVAQPDSAIIPHASGLPDELFQTDGQLT
HHCCCHHHHHHHHHHCCCEEHHHHCCCEECEEEEECCCCCCCCCCCCCCHHHHHCCCHHH
KRAIRAVTLSSLAPRGGELLWDIGAGSGSIGIEWLLAARSNRAIGIEARPDRLACARGNA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCEEEECCCC
DALGVPHFDLRLGQAPEALADLPTPDAVFIGGGAGNPGVLDAVWQALPPGGRLVVNAVTL
CCCCCCCCEEECCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEE
ETEALLIACHGRHGGELLRLGVERAAPVGGLTAWRAAIPVVQWSVRK
EEEEEEEEEECCCCCCEEEECHHHCCCCCCHHHHHHHCCEEEEECCC
>Mature Secondary Structure 
TATDDTPTPWLSIVGIGEDGVAGLSDKARALLANADLVIGGERHLAMVAALGRPTLPWR
CCCCCCCCCEEEEEEECCCCCCCCCHHHHEEEECCCEEECCCHHEEEEECCCCCCCCEE
VPFAVSLPDVLAQRGRSVVVLCSGDPFWHGAGAVLADHLAPSEWTALPAPSTFSWAAARL
CCEEECCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
GWRLEETITLGLHARPITMLRPHLQPGSRLIVLVRDGAAVAQIAAYLTATGFGPSSLTVL
CCEEEHEEEEECCCCCHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHH
EALGGPRERILRAAAANYTLTDVAAPVAIGIDVVAQPDSAIIPHASGLPDELFQTDGQLT
HHCCCHHHHHHHHHHCCCEEHHHHCCCEECEEEEECCCCCCCCCCCCCCHHHHHCCCHHH
KRAIRAVTLSSLAPRGGELLWDIGAGSGSIGIEWLLAARSNRAIGIEARPDRLACARGNA
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCEEEECCCC
DALGVPHFDLRLGQAPEALADLPTPDAVFIGGGAGNPGVLDAVWQALPPGGRLVVNAVTL
CCCCCCCCEEECCCCCHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEEE
ETEALLIACHGRHGGELLRLGVERAAPVGGLTAWRAAIPVVQWSVRK
EEEEEEEEEECCCCCCEEEECHHHCCCCCCHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]