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The map label for this gene is fnr [H]

Identifier: 86750261

GI number: 86750261

Start: 3604243

End: 3605001

Strand: Direct

Name: fnr [H]

Synonym: RPB_3150

Alternate gene names: 86750261

Gene position: 3604243-3605001 (Clockwise)

Preceding gene: 86750258

Following gene: 86750262

Centisome position: 67.6

GC content: 65.22

Gene sequence:

>759_bases
ATGGAAATGGGTGTTCGACACGAAGCCGTGGCGCACAGCGCGTTGTTCTCGCATCTCTCGGACGCGGAAGCGGCCCTGCT
GCTGAGAACATCGACCGTTCGGCAGATCCAGCCCGGCAACGCCCTCTTCCATCAGGGCGACGCTCCGGAGACTCTCTTCC
AGATCGTCGAGGGACTGGTCAGGGTCACCCAGATCAATACCGAAGGCGAGCAGATCACGCTCAGGATCATGGGGCCCGGC
GATCTGTGCTGCGTGGCCGCGATTCGACAGCAGTCTTATCCCGCGACAGCGACGGCCCTCAAGGACACCACCGTGCTGGC
CTGGCGCGGATGCACATTCATCGACATGGCCAATCAGCATCCGGCGATCGCCAACAACGTCCTCGCGATCGTCGGCAACC
GCGCGCACGAGATGCTGCAACGTGCCACCGAAATGACCGGCAAGTGCGTGTCCCAGAGAATCGCCGCCTGCCTGCTCCGG
CTGTCGGTCCAAGCCGGCGTCACAACCAGGGACGGAGTTCACATCGAAGCGCCGGTCACGCGCACCGATCTCGCCTCGAT
GGCGGGCCTCACCTACTTCACCGTCAGCCGCATCCTGAGTGCGTGGCAGAAGCAGGGCCTGGTGAAGAGCGGCCGGCAGC
GACTGACGATCCTCAACATGCCGCGGATCGCCGAGATCGCAGGACCGAGCCTGGAGCAGATCGCCGCCACCGCCTCTGCG
GCCGAGCGTCGCGGTGGCGGACACAGCCGCCAGCGGTGA

Upstream 100 bases:

>100_bases
GCGCCACGCTTAGAAGGCTTCAAAATACAACGCGTCATTCGTGCTGATAGGTCAGCAACAGGAGGAAGCGTCCGCCCTTG
AAAACAGTGACAGGTCTGCA

Downstream 100 bases:

>100_bases
CTTCGTCACAGACGCTGTGCGGCCCCTGTCCTAACGCTCCAGTGGTATCGTTGATTCACTCACAGCGGATCCGTCATGCC
GACCAAGATCTTCCTCGCGA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEMGVRHEAVAHSALFSHLSDAEAALLLRTSTVRQIQPGNALFHQGDAPETLFQIVEGLVRVTQINTEGEQITLRIMGPG
DLCCVAAIRQQSYPATATALKDTTVLAWRGCTFIDMANQHPAIANNVLAIVGNRAHEMLQRATEMTGKCVSQRIAACLLR
LSVQAGVTTRDGVHIEAPVTRTDLASMAGLTYFTVSRILSAWQKQGLVKSGRQRLTILNMPRIAEIAGPSLEQIAATASA
AERRGGGHSRQR

Sequences:

>Translated_252_residues
MEMGVRHEAVAHSALFSHLSDAEAALLLRTSTVRQIQPGNALFHQGDAPETLFQIVEGLVRVTQINTEGEQITLRIMGPG
DLCCVAAIRQQSYPATATALKDTTVLAWRGCTFIDMANQHPAIANNVLAIVGNRAHEMLQRATEMTGKCVSQRIAACLLR
LSVQAGVTTRDGVHIEAPVTRTDLASMAGLTYFTVSRILSAWQKQGLVKSGRQRLTILNMPRIAEIAGPSLEQIAATASA
AERRGGGHSRQR
>Mature_252_residues
MEMGVRHEAVAHSALFSHLSDAEAALLLRTSTVRQIQPGNALFHQGDAPETLFQIVEGLVRVTQINTEGEQITLRIMGPG
DLCCVAAIRQQSYPATATALKDTTVLAWRGCTFIDMANQHPAIANNVLAIVGNRAHEMLQRATEMTGKCVSQRIAACLLR
LSVQAGVTTRDGVHIEAPVTRTDLASMAGLTYFTVSRILSAWQKQGLVKSGRQRLTILNMPRIAEIAGPSLEQIAATASA
AERRGGGHSRQR

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=198, Percent_Identity=26.7676767676768, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27201; Mature: 27201

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMGVRHEAVAHSALFSHLSDAEAALLLRTSTVRQIQPGNALFHQGDAPETLFQIVEGLV
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHH
RVTQINTEGEQITLRIMGPGDLCCVAAIRQQSYPATATALKDTTVLAWRGCTFIDMANQH
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCEEEEECCCC
PAIANNVLAIVGNRAHEMLQRATEMTGKCVSQRIAACLLRLSVQAGVTTRDGVHIEAPVT
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
RTDLASMAGLTYFTVSRILSAWQKQGLVKSGRQRLTILNMPRIAEIAGPSLEQIAATASA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHCCCCHHHHHHHHHH
AERRGGGHSRQR
HHHCCCCCCCCC
>Mature Secondary Structure
MEMGVRHEAVAHSALFSHLSDAEAALLLRTSTVRQIQPGNALFHQGDAPETLFQIVEGLV
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHH
RVTQINTEGEQITLRIMGPGDLCCVAAIRQQSYPATATALKDTTVLAWRGCTFIDMANQH
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCEEEEECCCC
PAIANNVLAIVGNRAHEMLQRATEMTGKCVSQRIAACLLRLSVQAGVTTRDGVHIEAPVT
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
RTDLASMAGLTYFTVSRILSAWQKQGLVKSGRQRLTILNMPRIAEIAGPSLEQIAATASA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCHHHHCCCCHHHHHHHHHH
AERRGGGHSRQR
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA