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The map label for this gene is dgdR [H]

Identifier: 86749956

GI number: 86749956

Start: 3232042

End: 3232956

Strand: Direct

Name: dgdR [H]

Synonym: RPB_2839

Alternate gene names: 86749956

Gene position: 3232042-3232956 (Clockwise)

Preceding gene: 86749951

Following gene: 86749957

Centisome position: 60.62

GC content: 66.99

Gene sequence:

>915_bases
ATGCTCGCTCCTCTCGATCTTCGTCTGCTGCAGACCTTCATCGTCCTGGTTCAGACCGGTAGTTTCTCGGAAACCTCGCG
CCGGCTGGGACGCACCCAGCCAGCCGTCAGCTTGCAGCTCAACCGGCTGCAGGACGCGACCGGCGCGCCGCTGTTCACCA
AGGTCGGCCGCAAACTGGTGCTGACCAATCATGGCGAACTCGTTCTCGGCTATGCCCGGACCATCATGGGCCTGCAGGAC
GAGCTGCGCTCCCGCCTCGCCGCGCCGAAGCTCGACGGCATGGTGGTGCTCGGCATGCCGGATCTGTATGCGGCCTACCT
GCTGCCGGGGATCCTGGCCGACTTCCGCAGCGCCTATCCCAACGTGAATGTCGAGCTGAAATGCGCGCTGTCGAGCAAGC
TGATGGCCTCGGTCGAGCGCGCCGAGATCGATCTGGCGATCGTCACCGGAATGCCTGCCTTCAAGGTCGGCGAGCTGGTG
GCGCAGGAAGAGCTGGTCTGGGTGACGTCGGAGCGCGGCTCCGTCCACCTCGAGAATCCGGTGCCGCTCGCGATGCTGCC
GCCCGGCAACATCTTTCGCGATTTCGGCCTCGCGGCGCTGGAGAGCATCGGCCGGACCTGGCGGCTGCGCTGCATCAGCG
AAAGCATCGGCGGCATTCAGGCGGCCGTGTTTGCGGGAATCGCGGTCAGCGTGGTGGGGAAGAGTTCGGTGCTCCCGGGC
ATGCGCACATTGGGCCGCGGCGACACCTTTCCGGCGCTGCCCAAGGTCGATCTGGTGATGTACCGCTCGGCCCGCCGCGC
CAATCCGGCGGCGGAGGCGCTGGCCGGCGTGATCGTCCGACACTTCGCCAATTCCGCGCTGGCACCTTCAGCGCGCTTCG
TCCGCACCCAGGCCGGCAGCGGGTCGCACGATTAG

Upstream 100 bases:

>100_bases
ATCCTCGCTGCTGCAGTTCCGGCAAGCAACTGTAGGTGCGACGCAACAACTTCAGAAATTTATTGTTTATATCGATTTGA
TAAGCTGGCTTAATAGAACG

Downstream 100 bases:

>100_bases
TTCGAGCGATCACAGCAACCGGAGATGCGGCGTGCCGAAGGCGACGGCTGCGATCAGACCGATGGCGGCGCCGAGCACGA
TCAGGTCGGCATTGAGCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLQDATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRSRLAAPKLDGMVVLGMPDLYAAYLLPGILADFRSAYPNVNVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVTSERGSVHLENPVPLAMLPPGNIFRDFGLAALESIGRTWRLRCISESIGGIQAAVFAGIAVSVVGKSSVLPG
MRTLGRGDTFPALPKVDLVMYRSARRANPAAEALAGVIVRHFANSALAPSARFVRTQAGSGSHD

Sequences:

>Translated_304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLQDATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRSRLAAPKLDGMVVLGMPDLYAAYLLPGILADFRSAYPNVNVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVTSERGSVHLENPVPLAMLPPGNIFRDFGLAALESIGRTWRLRCISESIGGIQAAVFAGIAVSVVGKSSVLPG
MRTLGRGDTFPALPKVDLVMYRSARRANPAAEALAGVIVRHFANSALAPSARFVRTQAGSGSHD
>Mature_304_residues
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLQDATGAPLFTKVGRKLVLTNHGELVLGYARTIMGLQD
ELRSRLAAPKLDGMVVLGMPDLYAAYLLPGILADFRSAYPNVNVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELV
AQEELVWVTSERGSVHLENPVPLAMLPPGNIFRDFGLAALESIGRTWRLRCISESIGGIQAAVFAGIAVSVVGKSSVLPG
MRTLGRGDTFPALPKVDLVMYRSARRANPAAEALAGVIVRHFANSALAPSARFVRTQAGSGSHD

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=31.7343173431734, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788481, Length=277, Percent_Identity=26.3537906137184, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787806, Length=169, Percent_Identity=27.810650887574, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=28.8732394366197, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=147, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=28.4722222222222, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=298, Percent_Identity=26.1744966442953, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790399, Length=255, Percent_Identity=23.1372549019608, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32585; Mature: 32585

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLQDATGAPLFTKVGRKLV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHCCCEEE
LTNHGELVLGYARTIMGLQDELRSRLAAPKLDGMVVLGMPDLYAAYLLPGILADFRSAYP
EECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCC
NVNVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELVAQEELVWVTSERGSVHLENP
CCCEEEEEEHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCEEEEECCCCCEEECCC
VPLAMLPPGNIFRDFGLAALESIGRTWRLRCISESIGGIQAAVFAGIAVSVVGKSSVLPG
CCEEEECCCHHHHHHHHHHHHHCCHHEEEEEHHHHHCHHHHHHHHHHHHEECCCCCCCCC
MRTLGRGDTFPALPKVDLVMYRSARRANPAAEALAGVIVRHFANSALAPSARFVRTQAGS
HHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCC
GSHD
CCCC
>Mature Secondary Structure
MLAPLDLRLLQTFIVLVQTGSFSETSRRLGRTQPAVSLQLNRLQDATGAPLFTKVGRKLV
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHCCCEEE
LTNHGELVLGYARTIMGLQDELRSRLAAPKLDGMVVLGMPDLYAAYLLPGILADFRSAYP
EECCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCC
NVNVELKCALSSKLMASVERAEIDLAIVTGMPAFKVGELVAQEELVWVTSERGSVHLENP
CCCEEEEEEHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCEEEEECCCCCEEECCC
VPLAMLPPGNIFRDFGLAALESIGRTWRLRCISESIGGIQAAVFAGIAVSVVGKSSVLPG
CCEEEECCCHHHHHHHHHHHHHCCHHEEEEEHHHHHCHHHHHHHHHHHHEECCCCCCCCC
MRTLGRGDTFPALPKVDLVMYRSARRANPAAEALAGVIVRHFANSALAPSARFVRTQAGS
HHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCC
GSHD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]