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The map label for this gene is gltA [H]

Identifier: 86749930

GI number: 86749930

Start: 3206177

End: 3207481

Strand: Direct

Name: gltA [H]

Synonym: RPB_2813

Alternate gene names: 86749930

Gene position: 3206177-3207481 (Clockwise)

Preceding gene: 86749929

Following gene: 86749946

Centisome position: 60.13

GC content: 62.53

Gene sequence:

>1305_bases
ATGGACGCAACGACTAACAACAAGACAGCAACGCTCACGGTTGGAAACAACAGCTACGATCTTCCCATTCTGACCGGAAC
GGTGGGCCCCGATGTCGTCGACATCGGCAAGCTGTACGCTCAGACCGGGATGTTCACCTACGATCCGGGCTTCACCTCGA
CCGCGAGCTGCCAGTCCAAGATCACCTATATCGACGGCGACGCCGGCGTTCTCGAATATCGCGGTTATCCGATCGAGCAG
CTCGCCGAGAAGGGCGACTTCCTCGAGACCTGCTATCTCTTGCTGTACGGCGAATTGCCGACCAAGGCGCAGAAGGACGA
TTTCGACCTGCGCATCACCCGGCACACCATGGTGCACGAGCAGATGGCCCGGTTCTTCCAGGGCTTCCGCCGCGACGCGC
ACCCGATGGCGGTGATGGTCGCCTCGGTCGGCGCGCTGGCGGCGTTCTATCACGACTCCACCGACATCAACGATCCGAAG
CAGCGCATGATCGCGTCGATGCGGATGATCGCGAAGATCCCGACGCTGGCGGCGATGGCCTACAAGTACTCGATCGGCCA
GCCGTTCGTGTATCCGAAGAACTCGCTCTCCTTCGCCGGCAACTTCATCCATATGTGCTTCGCGGTGCCGTGCGAGGAGT
ACAAGGTCAATCCGGTCCTGTCGGCGGCGCTCGACAAGATCTTCACGCTGCACGCCGACCATGAGCAGAACGCCTCGACC
TCGACGGTGCGGATCGCCGGCTCCTCCGGCGCCAACCCGTTCGCCTGCATCGCGGCCGGCATCGCCTGCCTGTGGGGCCC
CGCGCATGGCGGCGCCAACGAAGCGGCGCTGGCGATGCTCAAGGAGATCGGCTCGGTCGACAACATTCCCGAGTTCATCG
CCAAGGTGAAGGACAAGAATTCGTCGGTGCGGCTGATGGGCTTCGGCCATCGCGTCTACAAGAACTACGATCCGCGCGCG
AAGATCATGCAGCAGGTCTGCCACGAAGTGCTGGCCGAAACCGGCCATCACGGCGACCCGCTGTTGAAGGTGGCGATGGA
GCTCGAGAAGATCGCCCTCAGCGATCCGTACTTCATCGATCGCAAGCTGTACCCGAACGTCGACTTCTATTCGGGCATCA
CGCTGAAGGCGATGGGCTTCCCGACCGACATGTTCACCGTGTTGTTCGCGGTGGCGCGCACCGTCGGCTGGATCAGCCAG
TGGAGCGAGATGATCGAGGATCCGCACCAGAAGATCGGCCGCCCGCGGCAGCTCTTCACCGGCGCGGCGCGACGCGAATA
TGTCGGGATCGACAAGCGCGGCTGA

Upstream 100 bases:

>100_bases
TAAGCTACGCCTTTCCAGTGTGCTTTTAGGACAACCAGTCTCGCTCGCATCTTCGGGTGCACCGCCTCTGGTTTCGACAA
CGAACATCGGGGACCACACG

Downstream 100 bases:

>100_bases
TCGCCTGAAGGTCTTCAGAAGGAACGGCGAACCGCCCAGGCGGTTCGCCGTTTTGCTTTGTGGCCCTCGCCCGGACGCCC
CCCGAGCGCAGCTTCAGTAA

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MDATTNNKTATLTVGNNSYDLPILTGTVGPDVVDIGKLYAQTGMFTYDPGFTSTASCQSKITYIDGDAGVLEYRGYPIEQ
LAEKGDFLETCYLLLYGELPTKAQKDDFDLRITRHTMVHEQMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPK
QRMIASMRMIAKIPTLAAMAYKYSIGQPFVYPKNSLSFAGNFIHMCFAVPCEEYKVNPVLSAALDKIFTLHADHEQNAST
STVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLKEIGSVDNIPEFIAKVKDKNSSVRLMGFGHRVYKNYDPRA
KIMQQVCHEVLAETGHHGDPLLKVAMELEKIALSDPYFIDRKLYPNVDFYSGITLKAMGFPTDMFTVLFAVARTVGWISQ
WSEMIEDPHQKIGRPRQLFTGAARREYVGIDKRG

Sequences:

>Translated_434_residues
MDATTNNKTATLTVGNNSYDLPILTGTVGPDVVDIGKLYAQTGMFTYDPGFTSTASCQSKITYIDGDAGVLEYRGYPIEQ
LAEKGDFLETCYLLLYGELPTKAQKDDFDLRITRHTMVHEQMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPK
QRMIASMRMIAKIPTLAAMAYKYSIGQPFVYPKNSLSFAGNFIHMCFAVPCEEYKVNPVLSAALDKIFTLHADHEQNAST
STVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLKEIGSVDNIPEFIAKVKDKNSSVRLMGFGHRVYKNYDPRA
KIMQQVCHEVLAETGHHGDPLLKVAMELEKIALSDPYFIDRKLYPNVDFYSGITLKAMGFPTDMFTVLFAVARTVGWISQ
WSEMIEDPHQKIGRPRQLFTGAARREYVGIDKRG
>Mature_434_residues
MDATTNNKTATLTVGNNSYDLPILTGTVGPDVVDIGKLYAQTGMFTYDPGFTSTASCQSKITYIDGDAGVLEYRGYPIEQ
LAEKGDFLETCYLLLYGELPTKAQKDDFDLRITRHTMVHEQMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPK
QRMIASMRMIAKIPTLAAMAYKYSIGQPFVYPKNSLSFAGNFIHMCFAVPCEEYKVNPVLSAALDKIFTLHADHEQNAST
STVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLKEIGSVDNIPEFIAKVKDKNSSVRLMGFGHRVYKNYDPRA
KIMQQVCHEVLAETGHHGDPLLKVAMELEKIALSDPYFIDRKLYPNVDFYSGITLKAMGFPTDMFTVLFAVARTVGWISQ
WSEMIEDPHQKIGRPRQLFTGAARREYVGIDKRG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=396, Percent_Identity=27.5252525252525, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786939, Length=425, Percent_Identity=66.5882352941177, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1786527, Length=365, Percent_Identity=30.4109589041096, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=406, Percent_Identity=27.0935960591133, Blast_Score=107, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319850, Length=331, Percent_Identity=26.5861027190332, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324328, Length=327, Percent_Identity=25.9938837920489, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325257, Length=403, Percent_Identity=25.5583126550869, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640126, Length=408, Percent_Identity=27.2058823529412, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24640124, Length=408, Percent_Identity=27.2058823529412, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356863, Length=356, Percent_Identity=27.8089887640449, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 47967; Mature: 47967

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATTNNKTATLTVGNNSYDLPILTGTVGPDVVDIGKLYAQTGMFTYDPGFTSTASCQSK
CCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCE
ITYIDGDAGVLEYRGYPIEQLAEKGDFLETCYLLLYGELPTKAQKDDFDLRITRHTMVHE
EEEEECCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHH
QMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPKQRMIASMRMIAKIPTLAAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNSLSFAGNFIHMCFAVPCEEYKVNPVLSAALDKIFTLHADHEQNAST
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHEEECCCCCCCCC
STVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLKEIGSVDNIPEFIAKVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SSVRLMGFGHRVYKNYDPRAKIMQQVCHEVLAETGHHGDPLLKVAMELEKIALSDPYFID
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEC
RKLYPNVDFYSGITLKAMGFPTDMFTVLFAVARTVGWISQWSEMIEDPHQKIGRPRQLFT
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHH
GAARREYVGIDKRG
HHHHHHCCCCCCCC
>Mature Secondary Structure
MDATTNNKTATLTVGNNSYDLPILTGTVGPDVVDIGKLYAQTGMFTYDPGFTSTASCQSK
CCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCE
ITYIDGDAGVLEYRGYPIEQLAEKGDFLETCYLLLYGELPTKAQKDDFDLRITRHTMVHE
EEEEECCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHH
QMARFFQGFRRDAHPMAVMVASVGALAAFYHDSTDINDPKQRMIASMRMIAKIPTLAAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNSLSFAGNFIHMCFAVPCEEYKVNPVLSAALDKIFTLHADHEQNAST
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHEEECCCCCCCCC
STVRIAGSSGANPFACIAAGIACLWGPAHGGANEAALAMLKEIGSVDNIPEFIAKVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SSVRLMGFGHRVYKNYDPRAKIMQQVCHEVLAETGHHGDPLLKVAMELEKIALSDPYFID
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEC
RKLYPNVDFYSGITLKAMGFPTDMFTVLFAVARTVGWISQWSEMIEDPHQKIGRPRQLFT
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHH
GAARREYVGIDKRG
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]