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The map label for this gene is moaC [H]

Identifier: 86749916

GI number: 86749916

Start: 3190449

End: 3190970

Strand: Direct

Name: moaC [H]

Synonym: RPB_2799

Alternate gene names: 86749916

Gene position: 3190449-3190970 (Clockwise)

Preceding gene: 86749915

Following gene: 86749917

Centisome position: 59.84

GC content: 66.09

Gene sequence:

>522_bases
ATGTCGAAGAAAGCGAAGCCGACCAGAGCCGCCGCCCCCGCCCTCACCCATATCGGCACCAGCGGCGAGGCGCGGATGGT
CGACGTCTCGGAGAAATCCGCGACCGAGCGCGTCGCAGTCGCCGAGGGCCGCGTGGTGATGAAGAAGGCTACACTGGACC
TGATCCTGAGTGGCGACGCCAAGAAGGGCGACGTGCTCGGCACGGCCCGGATCGCCGGCATCATGGCGGCCAAGCGCACT
TCGGAGCTGATCCCGCTGTGCCATCCGCTGGCGCTGTCGAAGGTCACGCTCGATATCGTCCCCGACAAGAAACTGCCCGG
CTGCATCGTCCGCGCCACGGTGAAGGTCACCGGCCCGACCGGCGTCGAGATGGAAGCGCTGACCGCGGTGTCGGTCGCCT
GCCTGACGATCTACGACATGATCAAGGCAGTGGAGCGCGGCGTGCGGATCGATGGCATTCACCTGATCGCCAAAACAGGC
GGCAAGTCCGGCGATTACGTCGCAGGGGCGGCGTCCAAATAG

Upstream 100 bases:

>100_bases
GGAATGTCGACCTTCCTGGTCGGCGAGAGCCTGATGCGTCAGGAGGACGTCGCCACCGCGACCCGCGCGCTGCTCGCGCG
CGCGGCCTGAGGCGGGGCTG

Downstream 100 bases:

>100_bases
GATAGGCTGCCGCGGCGATCACGAGAAAGATCACGCCGATGCCTCCCGTCTCGACACCAGCTTCCGCGCCCACCGGCCTC
AGCGAGGCTGAAGCCGGCGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSKKAKPTRAAAPALTHIGTSGEARMVDVSEKSATERVAVAEGRVVMKKATLDLILSGDAKKGDVLGTARIAGIMAAKRT
SELIPLCHPLALSKVTLDIVPDKKLPGCIVRATVKVTGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIDGIHLIAKTG
GKSGDYVAGAASK

Sequences:

>Translated_173_residues
MSKKAKPTRAAAPALTHIGTSGEARMVDVSEKSATERVAVAEGRVVMKKATLDLILSGDAKKGDVLGTARIAGIMAAKRT
SELIPLCHPLALSKVTLDIVPDKKLPGCIVRATVKVTGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIDGIHLIAKTG
GKSGDYVAGAASK
>Mature_172_residues
SKKAKPTRAAAPALTHIGTSGEARMVDVSEKSATERVAVAEGRVVMKKATLDLILSGDAKKGDVLGTARIAGIMAAKRTS
ELIPLCHPLALSKVTLDIVPDKKLPGCIVRATVKVTGPTGVEMEALTAVSVACLTIYDMIKAVERGVRIDGIHLIAKTGG
KSGDYVAGAASK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=56.578947368421, Blast_Score=163, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=152, Percent_Identity=44.078947368421, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=51.3513513513513, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.8248175182482, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17888; Mature: 17757

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKAKPTRAAAPALTHIGTSGEARMVDVSEKSATERVAVAEGRVVMKKATLDLILSGDA
CCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEEEEEEEECCC
KKGDVLGTARIAGIMAAKRTSELIPLCHPLALSKVTLDIVPDKKLPGCIVRATVKVTGPT
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCHHHCEEEEEEECCCCCCCEEEEEEEEEECCC
GVEMEALTAVSVACLTIYDMIKAVERGVRIDGIHLIAKTGGKSGDYVAGAASK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEECCCCCCCEECCCCCC
>Mature Secondary Structure 
SKKAKPTRAAAPALTHIGTSGEARMVDVSEKSATERVAVAEGRVVMKKATLDLILSGDA
CCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCEEEECCCEEEEEEEEEEEEEECCC
KKGDVLGTARIAGIMAAKRTSELIPLCHPLALSKVTLDIVPDKKLPGCIVRATVKVTGPT
CCCCEEEHHHHHHHHHHHHCCCCCCCCCCHHHCEEEEEEECCCCCCCEEEEEEEEEECCC
GVEMEALTAVSVACLTIYDMIKAVERGVRIDGIHLIAKTGGKSGDYVAGAASK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEECEEEEEEECCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9061023; 12597275 [H]