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The map label for this gene is nuoC [H]

Identifier: 86749692

GI number: 86749692

Start: 2955470

End: 2956084

Strand: Direct

Name: nuoC [H]

Synonym: RPB_2574

Alternate gene names: 86749692

Gene position: 2955470-2956084 (Clockwise)

Preceding gene: 86749691

Following gene: 86749693

Centisome position: 55.43

GC content: 65.85

Gene sequence:

>615_bases
ATGGACGACAACGGGCTCGACACCCTGGGTCAGACGATCGTCGGCGCCTTGCCGGGCGCCGCGATCGGTCATTCGATCGC
ATACGGCCAGCTGACGGTGACGATCGACGCCGCGAAGGTGGTGGAGGTGGCGCGTTTCCTGCGCGACGATCCGCGCTGCC
GCTTCGTCAACATCGTCGACGTCACCGCGGTCGACTATCCCGGCCGGGTGCCGCGGTTCGATCTGGTCTACCACTTCCTG
TCGCCGGCGCTGAACGCGCGGATCCGGCTGCGCGCCGAGGTCGGCGAGACCACGCTGGTGCCGTCGATCATCGACGTGTT
TCCGGGCACCGACTGGTTCGAGCGCGAGGTCTATGATCTCTACGGCATCGTCATCACCGGCCATCCCGACATGCGCCGGA
TTCTGACCGACTACGGGTTCGACGGTCACCCGCTGCGCAAGGACTTTCCGCTCACCGGTTTCGTCGAGGTCCGCTACGAC
GACGACCAGAAGCGCGTGGTCTACGAGCCGGTGCGGCTCAATCAGGAATTCCGCAAGTTCGACTTCCTGTCACCGTGGGA
AGGCGCGGACTATCCGGTGCTGCCGGGCGACGAGAAGGCGGGGGTGAAGCCGTGA

Upstream 100 bases:

>100_bases
TGCCCGCCGACCGCGGAAGCTCTGCTGTACGGCGTGATGCTGCTGCAGAAGAAGATCCGTCGGACCGGCACGATCGAACG
CTGAAGAAGAAGGCTGCTTC

Downstream 100 bases:

>100_bases
CGCCGATCGCCATGAACCACTCGCCATTCGCTACTCGCCCATCGCTGTTCGCCCGTGTGCGGAGCTTGCCCCATGGCTGA
CGCCGCTACCGAGGCCGCCG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MDDNGLDTLGQTIVGALPGAAIGHSIAYGQLTVTIDAAKVVEVARFLRDDPRCRFVNIVDVTAVDYPGRVPRFDLVYHFL
SPALNARIRLRAEVGETTLVPSIIDVFPGTDWFEREVYDLYGIVITGHPDMRRILTDYGFDGHPLRKDFPLTGFVEVRYD
DDQKRVVYEPVRLNQEFRKFDFLSPWEGADYPVLPGDEKAGVKP

Sequences:

>Translated_204_residues
MDDNGLDTLGQTIVGALPGAAIGHSIAYGQLTVTIDAAKVVEVARFLRDDPRCRFVNIVDVTAVDYPGRVPRFDLVYHFL
SPALNARIRLRAEVGETTLVPSIIDVFPGTDWFEREVYDLYGIVITGHPDMRRILTDYGFDGHPLRKDFPLTGFVEVRYD
DDQKRVVYEPVRLNQEFRKFDFLSPWEGADYPVLPGDEKAGVKP
>Mature_204_residues
MDDNGLDTLGQTIVGALPGAAIGHSIAYGQLTVTIDAAKVVEVARFLRDDPRCRFVNIVDVTAVDYPGRVPRFDLVYHFL
SPALNARIRLRAEVGETTLVPSIIDVFPGTDWFEREVYDLYGIVITGHPDMRRILTDYGFDGHPLRKDFPLTGFVEVRYD
DDQKRVVYEPVRLNQEFRKFDFLSPWEGADYPVLPGDEKAGVKP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=189, Percent_Identity=48.6772486772487, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI145693162, Length=157, Percent_Identity=34.3949044585987, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=183, Percent_Identity=47.5409836065574, Blast_Score=177, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI32563621, Length=183, Percent_Identity=47.5409836065574, Blast_Score=176, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24656494, Length=185, Percent_Identity=47.027027027027, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 23015; Mature: 23015

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNGLDTLGQTIVGALPGAAIGHSIAYGQLTVTIDAAKVVEVARFLRDDPRCRFVNIVD
CCCCHHHHHHHHHHHHCCCHHHCCEEEECEEEEEECHHHHHHHHHHHCCCCCEEEEEEEE
VTAVDYPGRVPRFDLVYHFLSPALNARIRLRAEVGETTLVPSIIDVFPGTDWFEREVYDL
EEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHEEE
YGIVITGHPDMRRILTDYGFDGHPLRKDFPLTGFVEVRYDDDQKRVVYEPVRLNQEFRKF
EEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECHHHCCHHHHHC
DFLSPWEGADYPVLPGDEKAGVKP
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDDNGLDTLGQTIVGALPGAAIGHSIAYGQLTVTIDAAKVVEVARFLRDDPRCRFVNIVD
CCCCHHHHHHHHHHHHCCCHHHCCEEEECEEEEEECHHHHHHHHHHHCCCCCEEEEEEEE
VTAVDYPGRVPRFDLVYHFLSPALNARIRLRAEVGETTLVPSIIDVFPGTDWFEREVYDL
EEEECCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHEEE
YGIVITGHPDMRRILTDYGFDGHPLRKDFPLTGFVEVRYDDDQKRVVYEPVRLNQEFRKF
EEEEEECCHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECHHHCCHHHHHC
DFLSPWEGADYPVLPGDEKAGVKP
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA