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The map label for this gene is yodQ [H]

Identifier: 86749626

GI number: 86749626

Start: 2867432

End: 2868712

Strand: Direct

Name: yodQ [H]

Synonym: RPB_2506

Alternate gene names: 86749626

Gene position: 2867432-2868712 (Clockwise)

Preceding gene: 86749624

Following gene: 86749627

Centisome position: 53.78

GC content: 65.5

Gene sequence:

>1281_bases
ATGAGCGTGTCCGACCTTCACCGCAGAATTCTCGATGCTGTCGATGCCGGCTTCGACGCACAACTGGCCACCACGCGCGA
TTTCGTCGCGATCCCGAGCACGCGGGGTGCCGAGGGTCCCTGCCAGGACATGATCGCCGATCTGTTGCGGCAACGCGGCT
ACGAGGTCGACGACTGGCATATCGAGGTCGACGACCTCAAGGACCTGCGCGGCTTCGGTCCGATCGAGCATGATTTCTCC
AAAGCGCGCACCGTGGTCGGCACCCATCGCCCTGCGAACAATCAGGGCCGCTCGCTGATCCTGCAGGGGCATTGCGACGT
CGTGCCGGCCGGGCCGCTGGAGATGTGGGCGACGCCGCCGTTCTCGCCGGTGGTCAAGGACGGCCGGATGTACGGCCGCG
GCGCCTGCGACATGAAGTCGGGCACGATCGGCGCGCTGTATGCGCTCGACGCAATCAAGGCCGCGGGGCTGACGCCGACC
GGGCGGATTCACTTCCAGTCGGTGATCGAGGAGGAGAGCACCGGCGTCGGCGCGTTGTCGACGCTGCAGCGGGGCTACCG
CGCCGATTGCTGCTTCATTCCCGAGCCGACCGATGGAAAGATGGTGCGTTCGCAGGTCGGCGTGATCTGGTTTCGCCTGA
AGGTGCGTGGTTTTCCCGTGCACGTGTTCGAAGCCGGCTCCGGCTCCAACGCCATCACCGCGGCCTATCATCTGATCCAC
GCGCTCGAGAAGCTCGAGGAGGATTGGAACAAGCGCGCCGTGAGCGATCCTCACTTCAAAAGCGTCGTGCATCCGATCAA
CTTCAACCCCGGCATCATCAAGGGCGGCGACTGGGCGTCCAGCGTGCCGGCCTGGTGCGACGTCGACTGCCGCATCGCGG
TTCTTCCGGGCTGGTCGGTCGCCGATCATCAGGCCGAGATCCTCGCCTGCGTCGCGGCGGCGGCGCGCGATCATCGCTTC
CTGTCGAACAATCCGCCGCAGGTGGAGTGGTCGGGCTTTCTGTCGGAGGGCTACGAGCTCACCAACTCCGCAGAGCCGGA
GGCCGCGTTCGGCAAGGCTTACGACGCGGTCTATGGCGGCGCGACGCCGGATCTGGTGTTCACGGCGCTGACCGATACGC
GGTTCTACGGGCTGAACTACGACATTCCGAGCCTGTGCTTCGGCGCCAGCGGCGCGGCGATGCACGGCTTCAACGAATAT
GTCGATCTGGAATCGCTACGCCAATCGACCAAGGCGACCGCCTTGTTCATCGCCGAATGGTGCGGGGTCGAGCCGGCCTA
G

Upstream 100 bases:

>100_bases
GGCTTGATTCGAACGCCCGGCCAAACTGTCTGCAAATTCCGGCGATCTGTGGTTTGATCGCGGCCGCCGGAGCAATCAAC
AACAATGGAGCAGCCGCCGC

Downstream 100 bases:

>100_bases
CGCCATGACCTGACAGGTTATTGCCTGCGGCGGGACGCCATGCATCCTGCCGCGGCAAGCTCAATGTGGACCAAAACAGA
GCCCGCGCCGCCTTGGGGCG

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSVSDLHRRILDAVDAGFDAQLATTRDFVAIPSTRGAEGPCQDMIADLLRQRGYEVDDWHIEVDDLKDLRGFGPIEHDFS
KARTVVGTHRPANNQGRSLILQGHCDVVPAGPLEMWATPPFSPVVKDGRMYGRGACDMKSGTIGALYALDAIKAAGLTPT
GRIHFQSVIEEESTGVGALSTLQRGYRADCCFIPEPTDGKMVRSQVGVIWFRLKVRGFPVHVFEAGSGSNAITAAYHLIH
ALEKLEEDWNKRAVSDPHFKSVVHPINFNPGIIKGGDWASSVPAWCDVDCRIAVLPGWSVADHQAEILACVAAAARDHRF
LSNNPPQVEWSGFLSEGYELTNSAEPEAAFGKAYDAVYGGATPDLVFTALTDTRFYGLNYDIPSLCFGASGAAMHGFNEY
VDLESLRQSTKATALFIAEWCGVEPA

Sequences:

>Translated_426_residues
MSVSDLHRRILDAVDAGFDAQLATTRDFVAIPSTRGAEGPCQDMIADLLRQRGYEVDDWHIEVDDLKDLRGFGPIEHDFS
KARTVVGTHRPANNQGRSLILQGHCDVVPAGPLEMWATPPFSPVVKDGRMYGRGACDMKSGTIGALYALDAIKAAGLTPT
GRIHFQSVIEEESTGVGALSTLQRGYRADCCFIPEPTDGKMVRSQVGVIWFRLKVRGFPVHVFEAGSGSNAITAAYHLIH
ALEKLEEDWNKRAVSDPHFKSVVHPINFNPGIIKGGDWASSVPAWCDVDCRIAVLPGWSVADHQAEILACVAAAARDHRF
LSNNPPQVEWSGFLSEGYELTNSAEPEAAFGKAYDAVYGGATPDLVFTALTDTRFYGLNYDIPSLCFGASGAAMHGFNEY
VDLESLRQSTKATALFIAEWCGVEPA
>Mature_425_residues
SVSDLHRRILDAVDAGFDAQLATTRDFVAIPSTRGAEGPCQDMIADLLRQRGYEVDDWHIEVDDLKDLRGFGPIEHDFSK
ARTVVGTHRPANNQGRSLILQGHCDVVPAGPLEMWATPPFSPVVKDGRMYGRGACDMKSGTIGALYALDAIKAAGLTPTG
RIHFQSVIEEESTGVGALSTLQRGYRADCCFIPEPTDGKMVRSQVGVIWFRLKVRGFPVHVFEAGSGSNAITAAYHLIHA
LEKLEEDWNKRAVSDPHFKSVVHPINFNPGIIKGGDWASSVPAWCDVDCRIAVLPGWSVADHQAEILACVAAAARDHRFL
SNNPPQVEWSGFLSEGYELTNSAEPEAAFGKAYDAVYGGATPDLVFTALTDTRFYGLNYDIPSLCFGASGAAMHGFNEYV
DLESLRQSTKATALFIAEWCGVEPA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=408, Percent_Identity=24.2647058823529, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788816, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789236, Length=224, Percent_Identity=25.4464285714286, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 46301; Mature: 46169

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSDLHRRILDAVDAGFDAQLATTRDFVAIPSTRGAEGPCQDMIADLLRQRGYEVDDWH
CCHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IEVDDLKDLRGFGPIEHDFSKARTVVGTHRPANNQGRSLILQGHCDVVPAGPLEMWATPP
EEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCHHHCCCCC
FSPVVKDGRMYGRGACDMKSGTIGALYALDAIKAAGLTPTGRIHFQSVIEEESTGVGALS
CCHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHH
TLQRGYRADCCFIPEPTDGKMVRSQVGVIWFRLKVRGFPVHVFEAGSGSNAITAAYHLIH
HHHCCCCCCEEECCCCCCCHHHHHHHCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHH
ALEKLEEDWNKRAVSDPHFKSVVHPINFNPGIIKGGDWASSVPAWCDVDCRIAVLPGWSV
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCC
ADHQAEILACVAAAARDHRFLSNNPPQVEWSGFLSEGYELTNSAEPEAAFGKAYDAVYGG
CHHHHHHHHHHHHHHHCCHHHCCCCCCEEECHHHHCCEECCCCCCCCHHHHHHHHHHCCC
ATPDLVFTALTDTRFYGLNYDIPSLCFGASGAAMHGFNEYVDLESLRQSTKATALFIAEW
CCHHHEEEEEECCEEEECCCCCHHHHHCCCCCHHCCCHHHHCHHHHHHHHHHHHEEEHHH
CGVEPA
CCCCCC
>Mature Secondary Structure 
SVSDLHRRILDAVDAGFDAQLATTRDFVAIPSTRGAEGPCQDMIADLLRQRGYEVDDWH
CHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IEVDDLKDLRGFGPIEHDFSKARTVVGTHRPANNQGRSLILQGHCDVVPAGPLEMWATPP
EEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCHHHCCCCC
FSPVVKDGRMYGRGACDMKSGTIGALYALDAIKAAGLTPTGRIHFQSVIEEESTGVGALS
CCHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHH
TLQRGYRADCCFIPEPTDGKMVRSQVGVIWFRLKVRGFPVHVFEAGSGSNAITAAYHLIH
HHHCCCCCCEEECCCCCCCHHHHHHHCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHH
ALEKLEEDWNKRAVSDPHFKSVVHPINFNPGIIKGGDWASSVPAWCDVDCRIAVLPGWSV
HHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEECCCCCCCCCCEECCCEEEEEECCCCC
ADHQAEILACVAAAARDHRFLSNNPPQVEWSGFLSEGYELTNSAEPEAAFGKAYDAVYGG
CHHHHHHHHHHHHHHHCCHHHCCCCCCEEECHHHHCCEECCCCCCCCHHHHHHHHHHCCC
ATPDLVFTALTDTRFYGLNYDIPSLCFGASGAAMHGFNEYVDLESLRQSTKATALFIAEW
CCHHHEEEEEECCEEEECCCCCHHHHHCCCCCHHCCCHHHHCHHHHHHHHHHHHEEEHHH
CGVEPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]