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The map label for this gene is engA [H]

Identifier: 86749568

GI number: 86749568

Start: 2803329

End: 2804708

Strand: Direct

Name: engA [H]

Synonym: RPB_2448

Alternate gene names: 86749568

Gene position: 2803329-2804708 (Clockwise)

Preceding gene: 86749567

Following gene: 86749569

Centisome position: 52.58

GC content: 66.67

Gene sequence:

>1380_bases
ATGTCATTCACATTCGCCATTATCGGCCGACCTAACGTCGGCAAGTCGACGCTGTTCAATCGTCTGGTCGGGCAGAAGCT
CGCGCTGGTCGACGACACTCCAGGCGTGACGCGCGATCGCCGCGAAGGCGAGGGGCGCCTCGGCGATCTCGAATTCACGA
TTATCGATACCGCTGGCCTCGACGAAGGCGCCAAGGGCTCGCTGACCGCGCGGATGCAGCAGCAGACCGAAACTGCGATC
GAACTCGCCGACGCGCTGATGTTCGTGTTCGACGCCCGCGCCGGCCTGACGCCGAACGACCGCGCCTTTGCCGATTTCGC
CCGCCGCGCCAACAAGCCCGTGGTCCTCGTCGCCAACAAGAGCGAAGGCAAGGCCGGCGGCATCGGCGCGATGGAGTCCT
ACGCGCTAGGTCTCGGCGACCCGGTGCAGATCTCCGCCGAGCACGGCGAGGGCCTCAGCGAACTCTACGACGCGCTGCGC
GCGATCATGCCGGAGCCGGAGGTCGAGGACGACGACGAGGAGATCGACGGCCTCACCGAGGAGGACTTCTCCAAGCGCCC
GATCCGGGTCGCGATCGTCGGCCGCCCGAACGCCGGCAAATCGACCTTCATCAACCGTCTGCTCGGCGAGGATCGGCTGC
TGACCAGCCCGGAGGCCGGCACCACGCGCGACTCGATCGCCGTCGAGGTGAACTGGAAAGGCCGCGAGTTCCGGATCTTC
GACACGGCCGGGCTGCGCCGCCGATCGCGGATCGAGGAGAAGCTCGAAAAGCTGTCGGTCGCCGATGCGCTGCGCGCGGT
GCGTTTCGCCGAAGTCGTGGTGCTGATGATGGATTCGCAGAACCGCTTCGAGGAGCAGGATCTGCGCATCGCCGACCTGA
TCGAGCGCGAGGGCCGCGCGCTGGTGATCGCGGTCAACAAATGGGATCTGGTCGAGCAGCAGGGCGGGCAGATCGCGCAG
TTGCGCGCCGACGCCGATCACTGGCTGCCCCAGGTCCGCGGCGTGCCGATCGTCGCGACCTCCGGGATGCTCGGCGAGGG
CGTCGACCGGCTGATCGATGCGATCCAGGACGCCTATGCGGTGTGGAATACGCGGGTGTCGACGGCAGCGCTGAACCGCT
GGTTCGAGCAGGCGGTGGCGCAAAATCCGCCGCCGGCGGTCGCGGGTCGCCGGCTGAAGCTGAACTACGTCACCCAGACC
AAGGCGCGACCGCCGAGCTTCGTGGTGTTCTGTTCGCGCGCCGACGCGGTGCCGGAATCCTATCTGCGCTATCTGGTCAA
CAGTCTGCGCGGCGTGTTCAAACTGCCGGGCACGCCGGTCCGCATCACGCTGCGCGAAAAGGCCAATCCTTTCGCCCACA
AGCGCAAACGGAAATCATGA

Upstream 100 bases:

>100_bases
CCTTGCCGAGCGGTACTTTCCAGCGCTGATCCGACCTTGGGGGCTCCTCCGGCGTCCCGCGACATTGACAGGCCACCGCT
TCTCGGCGCACGGATCAGCC

Downstream 100 bases:

>100_bases
CCGCGGCCGGCCACGCGAGCGGGACGAGCGCGCCGGCACCCGGCGCGCGCCCCGCCGCGGTCGGCTTCATCTTCGTCACC
ATCCTGCTCGACATGCTGAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGLDEGAKGSLTARMQQQTETAI
ELADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANKSEGKAGGIGAMESYALGLGDPVQISAEHGEGLSELYDALR
AIMPEPEVEDDDEEIDGLTEEDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGREFRIF
DTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRALVIAVNKWDLVEQQGGQIAQ
LRADADHWLPQVRGVPIVATSGMLGEGVDRLIDAIQDAYAVWNTRVSTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQT
KARPPSFVVFCSRADAVPESYLRYLVNSLRGVFKLPGTPVRITLREKANPFAHKRKRKS

Sequences:

>Translated_459_residues
MSFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGLDEGAKGSLTARMQQQTETAI
ELADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANKSEGKAGGIGAMESYALGLGDPVQISAEHGEGLSELYDALR
AIMPEPEVEDDDEEIDGLTEEDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGREFRIF
DTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRALVIAVNKWDLVEQQGGQIAQ
LRADADHWLPQVRGVPIVATSGMLGEGVDRLIDAIQDAYAVWNTRVSTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQT
KARPPSFVVFCSRADAVPESYLRYLVNSLRGVFKLPGTPVRITLREKANPFAHKRKRKS
>Mature_458_residues
SFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGLDEGAKGSLTARMQQQTETAIE
LADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANKSEGKAGGIGAMESYALGLGDPVQISAEHGEGLSELYDALRA
IMPEPEVEDDDEEIDGLTEEDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGREFRIFD
TAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRALVIAVNKWDLVEQQGGQIAQL
RADADHWLPQVRGVPIVATSGMLGEGVDRLIDAIQDAYAVWNTRVSTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQTK
ARPPSFVVFCSRADAVPESYLRYLVNSLRGVFKLPGTPVRITLREKANPFAHKRKRKS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=40.7725321888412, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=31.9277108433735, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI2367268, Length=167, Percent_Identity=31.7365269461078, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=131, Percent_Identity=31.2977099236641, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=176, Percent_Identity=28.4090909090909, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50724; Mature: 50593

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGL
CCEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCC
DEGAKGSLTARMQQQTETAIELADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
SEGKAGGIGAMESYALGLGDPVQISAEHGEGLSELYDALRAIMPEPEVEDDDEEIDGLTE
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
EDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGREFRIF
HHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCEEEEE
DTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHCCCCE
LVIAVNKWDLVEQQGGQIAQLRADADHWLPQVRGVPIVATSGMLGEGVDRLIDAIQDAYA
EEEEECCCHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
VWNTRVSTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQTKARPPSFVVFCSRADAVPES
HHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCHHH
YLRYLVNSLRGVFKLPGTPVRITLREKANPFAHKRKRKS
HHHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHHCCCC
>Mature Secondary Structure 
SFTFAIIGRPNVGKSTLFNRLVGQKLALVDDTPGVTRDRREGEGRLGDLEFTIIDTAGL
CEEEEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCC
DEGAKGSLTARMQQQTETAIELADALMFVFDARAGLTPNDRAFADFARRANKPVVLVANK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
SEGKAGGIGAMESYALGLGDPVQISAEHGEGLSELYDALRAIMPEPEVEDDDEEIDGLTE
CCCCCCCCCCHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCC
EDFSKRPIRVAIVGRPNAGKSTFINRLLGEDRLLTSPEAGTTRDSIAVEVNWKGREFRIF
HHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCEEEEE
DTAGLRRRSRIEEKLEKLSVADALRAVRFAEVVVLMMDSQNRFEEQDLRIADLIEREGRA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHCCCCE
LVIAVNKWDLVEQQGGQIAQLRADADHWLPQVRGVPIVATSGMLGEGVDRLIDAIQDAYA
EEEEECCCHHHHHCCCCEEEEECCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
VWNTRVSTAALNRWFEQAVAQNPPPAVAGRRLKLNYVTQTKARPPSFVVFCSRADAVPES
HHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCHHH
YLRYLVNSLRGVFKLPGTPVRITLREKANPFAHKRKRKS
HHHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA