Click here to switch to the map view.

The map label for this gene is hipO [H]

Identifier: 86749247

GI number: 86749247

Start: 2418572

End: 2419744

Strand: Reverse

Name: hipO [H]

Synonym: RPB_2126

Alternate gene names: 86749247

Gene position: 2419744-2418572 (Counterclockwise)

Preceding gene: 86749248

Following gene: 86749246

Centisome position: 45.38

GC content: 66.92

Gene sequence:

>1173_bases
ATGCCGACCATCGACCGTATCGATGCCTTCGCCGACGAACTGACCGCGATCCGCCGCGATCTCCACATGCATCCGGAAAT
CGGCTTCGAGGAGGTCCGCACCTCCAACATCGTCGCCGAAAAGCTCGACCAATGGGGCATCGAGGTGCATCGCGGGCTCG
GCGGCACCGGCGTGGTCGGCGTGCTGAAGGGCAAAGGCTCGGCAGGCCGCCGCATCGGCCTGCGCGCCGACATGGATGCG
CTGCCGATGGAGGAGCACACCAATCTGGCGTGGCGCTCGACCATTCCCGGCCGCTTCCACGGCTGCGGCCATGACGCCCA
CACCACCATGCTGCTCGGCACCGCGCGGTATCTCGCCGAGACCCGCAATTTCGACGGCACCGTGCATTTCATCTTCCAGC
CGGCCGAGGAAGGCCTCGGCGGCGCGCGCGCGATGCTGAAGGACGGGCTGTTCCAGAAATTCCCCTGCGACGAACTCTAC
GGCCTGCACAACGCCCCCGACCTGGCCCATGGCGAGATCGCGATCCTGCCCGGGCCGGCAATGGCCGGAGCCGACTTCTT
CGACATCACCATCTCGGGCTACGGCGCCCACGGCGCGATGCCGGAGCGCTCCAAGGACCCCGTGGTGATCGCGATGACGC
TGGGGCAAGCGCTGCAGACCATCGTCAGCCGCAACGTCGATCCGTTGCAATCGGCGGTGCTGTCGATCACCCAGATCCAT
TCCGGCTCGGCCTATAACGTCATCCCCGGCGAAGCGCGGCTCGCCGGCACCGTCCGCGCCTTCTCCGACGACGTGCGCAA
GCTGGTGCGCGAGCGGATGCGGGCGCTGGCCGCCGGCATCGCGGCGGCGTTCGACGTCGAAATCAAGGTCGAGATCCGCG
ACATCTTCAGCGTGCTGGTGAATCAGCAGGCGCAGAGCGAGGTGGTCGCCGAAGTCGCGCGCAGCGTGGTCGGCGAGGCC
AATGTCATCACCCGCTCGCAGCCGAAGATGGGCAGCGAGGATTTCGCCGACATGCTGCAGGCGATCCCCGGCGCTTACTT
CTGGGTCGGCCATGACGGCGACGTGCCGGTGCACAATCCCGGCTACGTGCTCGACGACAAGATCCTGCCGATCGGCGCAT
CGATGTTCGCGCGGATCATCGAAACCCGTCTGCCGGTGGCCGCCAATGTCTGA

Upstream 100 bases:

>100_bases
CGCTTTGCCCGATCCTTGCATGCAGGCCGCAGCCGCTCTCGGCCGCACGCTGCGCAGCAACCCGCGATTCACATCTGCGA
CCCCAAAGGTGACCCCCGAC

Downstream 100 bases:

>100_bases
CGGTTTGACGAGCAAGACCACCGCGCTGCACGACCTCAGCGCCACCGAACTGCTGGCCGGCTACTACGCCAAACAGTTCT
CGCCGTCGGAGGTGATCGAC

Product: peptidase M20D, amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPTIDRIDAFADELTAIRRDLHMHPEIGFEEVRTSNIVAEKLDQWGIEVHRGLGGTGVVGVLKGKGSAGRRIGLRADMDA
LPMEEHTNLAWRSTIPGRFHGCGHDAHTTMLLGTARYLAETRNFDGTVHFIFQPAEEGLGGARAMLKDGLFQKFPCDELY
GLHNAPDLAHGEIAILPGPAMAGADFFDITISGYGAHGAMPERSKDPVVIAMTLGQALQTIVSRNVDPLQSAVLSITQIH
SGSAYNVIPGEARLAGTVRAFSDDVRKLVRERMRALAAGIAAAFDVEIKVEIRDIFSVLVNQQAQSEVVAEVARSVVGEA
NVITRSQPKMGSEDFADMLQAIPGAYFWVGHDGDVPVHNPGYVLDDKILPIGASMFARIIETRLPVAANV

Sequences:

>Translated_390_residues
MPTIDRIDAFADELTAIRRDLHMHPEIGFEEVRTSNIVAEKLDQWGIEVHRGLGGTGVVGVLKGKGSAGRRIGLRADMDA
LPMEEHTNLAWRSTIPGRFHGCGHDAHTTMLLGTARYLAETRNFDGTVHFIFQPAEEGLGGARAMLKDGLFQKFPCDELY
GLHNAPDLAHGEIAILPGPAMAGADFFDITISGYGAHGAMPERSKDPVVIAMTLGQALQTIVSRNVDPLQSAVLSITQIH
SGSAYNVIPGEARLAGTVRAFSDDVRKLVRERMRALAAGIAAAFDVEIKVEIRDIFSVLVNQQAQSEVVAEVARSVVGEA
NVITRSQPKMGSEDFADMLQAIPGAYFWVGHDGDVPVHNPGYVLDDKILPIGASMFARIIETRLPVAANV
>Mature_389_residues
PTIDRIDAFADELTAIRRDLHMHPEIGFEEVRTSNIVAEKLDQWGIEVHRGLGGTGVVGVLKGKGSAGRRIGLRADMDAL
PMEEHTNLAWRSTIPGRFHGCGHDAHTTMLLGTARYLAETRNFDGTVHFIFQPAEEGLGGARAMLKDGLFQKFPCDELYG
LHNAPDLAHGEIAILPGPAMAGADFFDITISGYGAHGAMPERSKDPVVIAMTLGQALQTIVSRNVDPLQSAVLSITQIHS
GSAYNVIPGEARLAGTVRAFSDDVRKLVRERMRALAAGIAAAFDVEIKVEIRDIFSVLVNQQAQSEVVAEVARSVVGEAN
VITRSQPKMGSEDFADMLQAIPGAYFWVGHDGDVPVHNPGYVLDDKILPIGASMFARIIETRLPVAANV

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=425, Percent_Identity=26.5882352941176, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42102; Mature: 41970

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTIDRIDAFADELTAIRRDLHMHPEIGFEEVRTSNIVAEKLDQWGIEVHRGLGGTGVVG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEE
VLKGKGSAGRRIGLRADMDALPMEEHTNLAWRSTIPGRFHGCGHDAHTTMLLGTARYLAE
EEECCCCCCCEECCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
TRNFDGTVHFIFQPAEEGLGGARAMLKDGLFQKFPCDELYGLHNAPDLAHGEIAILPGPA
HCCCCCEEEEEEECCHHCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEECCCC
MAGADFFDITISGYGAHGAMPERSKDPVVIAMTLGQALQTIVSRNVDPLQSAVLSITQIH
CCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHC
SGSAYNVIPGEARLAGTVRAFSDDVRKLVRERMRALAAGIAAAFDVEIKVEIRDIFSVLV
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHH
NQQAQSEVVAEVARSVVGEANVITRSQPKMGSEDFADMLQAIPGAYFWVGHDGDVPVHNP
CCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCC
GYVLDDKILPIGASMFARIIETRLPVAANV
CEEECCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTIDRIDAFADELTAIRRDLHMHPEIGFEEVRTSNIVAEKLDQWGIEVHRGLGGTGVVG
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCEEE
VLKGKGSAGRRIGLRADMDALPMEEHTNLAWRSTIPGRFHGCGHDAHTTMLLGTARYLAE
EEECCCCCCCEECCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
TRNFDGTVHFIFQPAEEGLGGARAMLKDGLFQKFPCDELYGLHNAPDLAHGEIAILPGPA
HCCCCCEEEEEEECCHHCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCEEEECCCC
MAGADFFDITISGYGAHGAMPERSKDPVVIAMTLGQALQTIVSRNVDPLQSAVLSITQIH
CCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHC
SGSAYNVIPGEARLAGTVRAFSDDVRKLVRERMRALAAGIAAAFDVEIKVEIRDIFSVLV
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHH
NQQAQSEVVAEVARSVVGEANVITRSQPKMGSEDFADMLQAIPGAYFWVGHDGDVPVHNP
CCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCC
GYVLDDKILPIGASMFARIIETRLPVAANV
CEEECCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]