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The map label for this gene is prmA [H]

Identifier: 86749135

GI number: 86749135

Start: 2289658

End: 2290548

Strand: Reverse

Name: prmA [H]

Synonym: RPB_2012

Alternate gene names: 86749135

Gene position: 2290548-2289658 (Counterclockwise)

Preceding gene: 86749137

Following gene: 86749133

Centisome position: 42.96

GC content: 72.28

Gene sequence:

>891_bases
ATGCCTGATCCCGCCCCCACCACCCGCGCCAGCTTCGTGATCGGCGACGAGGCCACCGCGCGCCGGATGACCGATCTGCT
CGGCGAGAGACTGGGCGAGGGCGAACTGGCGATCGCGGCGTTCGAGCGCCCGGATCGCGCCTGGGAGGTCAGCCTGCATT
TCGGCGAGGGGCCGGATCTCGACGGCATCCGCGCGCTGGTCGCGCAGGTGGCAGGCGACGCCGCTTCGGCCGCCATGACG
GTCGAGACCATCGCGGCCAAGGACTGGGTGGCGGCCAGCCTCGAAGGGCTGGTCCCCGTCCCGGCCGGCCGCTTCATCGT
CCATGGCAGCCATGACCGCGCCCGCATCCCGCCGAACAAGCTCGGTATCGAGATCGAGGCGGCGCTGGCCTTCGGCACCG
GCCATCACGGCACCACCCGCGGCTGCCTGACGCTGCTCGATCTGGTGCTGCGCGCCGGCCCGCCGCGCAGCGTGCTCGAC
CTCGGCACCGGCACCGGCGTGCTGGCGATCGCTGCCGCCAAGGCGCTGCGCCAGCCGGTGCTGGCGACCGACATCGACCG
GCAGTCGGTCGCCGTCGCCAGGGAGAACGCGCGACTCAACGGCGTCGGCAATCTGGTGCACGCCGAATGGGCCACCGGCT
TCGCCTCGCCGGCCTTCGCCGCCCATGCGCCGTTCGACCTGGTGCTGGCGAATATTCTGGCCAACCCGCTGCGCGCGCTG
GCGCAGCCGATGTCCGAGCATCTGGCGCCGTCGGCGCTGGTGATCCTGTCCGGCCTGCTGCAGCCGCAGGCGCAGAGCGT
GATCGCGGCCTATCGCGCGCGCGGCTGCGTGCTGCTCCGGCAGATCGTGATCGAGGGCTGGAGCAGCCTGCTGCTGGCCA
AGACGTTCTGA

Upstream 100 bases:

>100_bases
GGTAAGTCGTGGACAAACCCTGCCTTTCGGGCGCAGAAACTGGGGACATTGGGTTGTCCATCACATCAACGACGCTCCCC
TGCCAACCATCGGACCTGCC

Downstream 100 bases:

>100_bases
TGGCGAAGACGTTCTGAGGACTACTTCCCGGGCGGCTTGGGGAAGCGGACATAGACGCCGTCCTTCGGCACCGCGCGCTT
GCCGCGCGCCTCGGCCAGCC

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPDPAPTTRASFVIGDEATARRMTDLLGERLGEGELAIAAFERPDRAWEVSLHFGEGPDLDGIRALVAQVAGDAASAAMT
VETIAAKDWVAASLEGLVPVPAGRFIVHGSHDRARIPPNKLGIEIEAALAFGTGHHGTTRGCLTLLDLVLRAGPPRSVLD
LGTGTGVLAIAAAKALRQPVLATDIDRQSVAVARENARLNGVGNLVHAEWATGFASPAFAAHAPFDLVLANILANPLRAL
AQPMSEHLAPSALVILSGLLQPQAQSVIAAYRARGCVLLRQIVIEGWSSLLLAKTF

Sequences:

>Translated_296_residues
MPDPAPTTRASFVIGDEATARRMTDLLGERLGEGELAIAAFERPDRAWEVSLHFGEGPDLDGIRALVAQVAGDAASAAMT
VETIAAKDWVAASLEGLVPVPAGRFIVHGSHDRARIPPNKLGIEIEAALAFGTGHHGTTRGCLTLLDLVLRAGPPRSVLD
LGTGTGVLAIAAAKALRQPVLATDIDRQSVAVARENARLNGVGNLVHAEWATGFASPAFAAHAPFDLVLANILANPLRAL
AQPMSEHLAPSALVILSGLLQPQAQSVIAAYRARGCVLLRQIVIEGWSSLLLAKTF
>Mature_295_residues
PDPAPTTRASFVIGDEATARRMTDLLGERLGEGELAIAAFERPDRAWEVSLHFGEGPDLDGIRALVAQVAGDAASAAMTV
ETIAAKDWVAASLEGLVPVPAGRFIVHGSHDRARIPPNKLGIEIEAALAFGTGHHGTTRGCLTLLDLVLRAGPPRSVLDL
GTGTGVLAIAAAKALRQPVLATDIDRQSVAVARENARLNGVGNLVHAEWATGFASPAFAAHAPFDLVLANILANPLRALA
QPMSEHLAPSALVILSGLLQPQAQSVIAAYRARGCVLLRQIVIEGWSSLLLAKTF

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=218, Percent_Identity=33.0275229357798, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30971; Mature: 30840

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPAPTTRASFVIGDEATARRMTDLLGERLGEGELAIAAFERPDRAWEVSLHFGEGPDL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCH
DGIRALVAQVAGDAASAAMTVETIAAKDWVAASLEGLVPVPAGRFIVHGSHDRARIPPNK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHH
LGIEIEAALAFGTGHHGTTRGCLTLLDLVLRAGPPRSVLDLGTGTGVLAIAAAKALRQPV
HCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCH
LATDIDRQSVAVARENARLNGVGNLVHAEWATGFASPAFAAHAPFDLVLANILANPLRAL
HHCCCCHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHH
AQPMSEHLAPSALVILSGLLQPQAQSVIAAYRARGCVLLRQIVIEGWSSLLLAKTF
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDPAPTTRASFVIGDEATARRMTDLLGERLGEGELAIAAFERPDRAWEVSLHFGEGPDL
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCH
DGIRALVAQVAGDAASAAMTVETIAAKDWVAASLEGLVPVPAGRFIVHGSHDRARIPPNK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHH
LGIEIEAALAFGTGHHGTTRGCLTLLDLVLRAGPPRSVLDLGTGTGVLAIAAAKALRQPV
HCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHCCH
LATDIDRQSVAVARENARLNGVGNLVHAEWATGFASPAFAAHAPFDLVLANILANPLRAL
HHCCCCHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHH
AQPMSEHLAPSALVILSGLLQPQAQSVIAAYRARGCVLLRQIVIEGWSSLLLAKTF
HHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA