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The map label for this gene is arsM [H]

Identifier: 86749091

GI number: 86749091

Start: 2235797

End: 2236627

Strand: Reverse

Name: arsM [H]

Synonym: RPB_1968

Alternate gene names: 86749091

Gene position: 2236627-2235797 (Counterclockwise)

Preceding gene: 86749092

Following gene: 86749088

Centisome position: 41.95

GC content: 68.95

Gene sequence:

>831_bases
ATGTCGACCACCGAGATCACCGAAATCGTCCGTGAGAAATACGCCGCGGCCGCCACCCGCGCCGGATCGTGCTGCGGCGC
CCCTGCCCTCGACCATGTCAGCCCGATCACCAGCAATCTCTACGACGCCGCGCAGGCCGAGGGGCTGCCCGCCGAAGCCA
TGCTGGCCTCGCTCGGCTGCGGCAATCCGACCGCGCTGGCCGAGCTGAAGCCCGGCGAGACGGTGCTCGATCTCGGCTCC
GGCGGCGGCATCGACGTGCTGCTGTCGGCGCGCCGGGTCGGCCCCACCGGCAAGGCCTACGGCCTCGACATGACCGACGA
GATGCTGGCGCTGGCGCGCGACAATCAGCGCAAGGCCGGCGCCGATAACGTCGAATTCCTCAAGGGCCAGATCGAGGCGA
TCCCGCTGCCGGACAATTCGGTCGACGTCATCATCTCGAACTGCGTCATCAACCTGTCGGGCGACAAGGACCGTGTGCTG
CGCGAAGCCTTCCGCGTGCTCAAGCCCGGCGGCCGTTTCGCCGTCTCCGACGTGGTGACGCGCGGCGAGATTCCCGAACA
GTTGCGTAGCGACGTGCTGCTGTGGGTCGGCTGCCTCGCCGGCGCGCTGGACGAGGCCGACTACACCGCGAAGCTCGCGG
CCGTCGGCTTCCGCGACGTGTCGATCGAGCCGACCCGGATCTACAAGGTGGACGACGCCCGCGACTTCCTCGAAGGCCGC
GGCCTCGACGTCGACGCGATCGCGCCGCAGATCGACGGCAAATTCTTCAGCGGCTTCGTCCGCGCCACCAAGCCGGGGGC
GACTGCCGGCGGCTGCTGTTCCAGTTCGTGA

Upstream 100 bases:

>100_bases
CCGCCTGACGTCGTCAGGCCCGTTTATTCGATCATTCTAGTTCGATCGAATTAGCAGAAACTGTCCGTCGTTCTGCCGAA
CAACCACGAGGAGAACCGCC

Downstream 100 bases:

>100_bases
TCATCGCGACGGCGCGCCGATCTTGCGACCGGCGCGCCAGTCACGCACCACGACCTCGCCGCGCGACGGGGCCGGCGCGG
ACACAACGAGCGATCAACCC

Product: arsenite S-adenosylmethyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSTTEITEIVREKYAAAATRAGSCCGAPALDHVSPITSNLYDAAQAEGLPAEAMLASLGCGNPTALAELKPGETVLDLGS
GGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAGADNVEFLKGQIEAIPLPDNSVDVIISNCVINLSGDKDRVL
REAFRVLKPGGRFAVSDVVTRGEIPEQLRSDVLLWVGCLAGALDEADYTAKLAAVGFRDVSIEPTRIYKVDDARDFLEGR
GLDVDAIAPQIDGKFFSGFVRATKPGATAGGCCSSS

Sequences:

>Translated_276_residues
MSTTEITEIVREKYAAAATRAGSCCGAPALDHVSPITSNLYDAAQAEGLPAEAMLASLGCGNPTALAELKPGETVLDLGS
GGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAGADNVEFLKGQIEAIPLPDNSVDVIISNCVINLSGDKDRVL
REAFRVLKPGGRFAVSDVVTRGEIPEQLRSDVLLWVGCLAGALDEADYTAKLAAVGFRDVSIEPTRIYKVDDARDFLEGR
GLDVDAIAPQIDGKFFSGFVRATKPGATAGGCCSSS
>Mature_275_residues
STTEITEIVREKYAAAATRAGSCCGAPALDHVSPITSNLYDAAQAEGLPAEAMLASLGCGNPTALAELKPGETVLDLGSG
GGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAGADNVEFLKGQIEAIPLPDNSVDVIISNCVINLSGDKDRVLR
EAFRVLKPGGRFAVSDVVTRGEIPEQLRSDVLLWVGCLAGALDEADYTAKLAAVGFRDVSIEPTRIYKVDDARDFLEGRG
LDVDAIAPQIDGKFFSGFVRATKPGATAGGCCSSS

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI109389364, Length=222, Percent_Identity=34.6846846846847, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI48994983, Length=108, Percent_Identity=41.6666666666667, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28892; Mature: 28761

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTEITEIVREKYAAAATRAGSCCGAPALDHVSPITSNLYDAAQAEGLPAEAMLASLGC
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
GNPTALAELKPGETVLDLGSGGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAG
CCCCEEEEECCCCEEEECCCCCCEEEEEEHHHCCCCCCEECCCCHHHHHHHHHCCCCCCC
ADNVEFLKGQIEAIPLPDNSVDVIISNCVINLSGDKDRVLREAFRVLKPGGRFAVSDVVT
CCCHHHHHCCEEEEECCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEHHHHHH
RGEIPEQLRSDVLLWVGCLAGALDEADYTAKLAAVGFRDVSIEPTRIYKVDDARDFLEGR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHCC
GLDVDAIAPQIDGKFFSGFVRATKPGATAGGCCSSS
CCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STTEITEIVREKYAAAATRAGSCCGAPALDHVSPITSNLYDAAQAEGLPAEAMLASLGC
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
GNPTALAELKPGETVLDLGSGGGIDVLLSARRVGPTGKAYGLDMTDEMLALARDNQRKAG
CCCCEEEEECCCCEEEECCCCCCEEEEEEHHHCCCCCCEECCCCHHHHHHHHHCCCCCCC
ADNVEFLKGQIEAIPLPDNSVDVIISNCVINLSGDKDRVLREAFRVLKPGGRFAVSDVVT
CCCHHHHHCCEEEEECCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEHHHHHH
RGEIPEQLRSDVLLWVGCLAGALDEADYTAKLAAVGFRDVSIEPTRIYKVDDARDFLEGR
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHCC
GLDVDAIAPQIDGKFFSGFVRATKPGATAGGCCSSS
CCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA