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The map label for this gene is pip [H]

Identifier: 86749017

GI number: 86749017

Start: 2168876

End: 2169865

Strand: Reverse

Name: pip [H]

Synonym: RPB_1894

Alternate gene names: 86749017

Gene position: 2169865-2168876 (Counterclockwise)

Preceding gene: 86749024

Following gene: 86749016

Centisome position: 40.7

GC content: 66.57

Gene sequence:

>990_bases
ATGGCACCCGACGCAAAATCCGAGATCCGGTCCGACGACAGCACCAAGGCCGCAGCGCCGCTCAGCTCTCGAATGCTCGC
GGTCGGCGACGGCCATGAAATCTATGTCGAAACCAACGGTAACGCCGACGGTCTTCCCGCGGTCTATCTGCATGGCGGCC
CGGGAAGCGGTTGTCAGCCGGACCACCGGAGGCTGTTCGATCCGCGGCGGTTTCACGCCGTGCTGTTCGATCAGCGCGGC
GCCGGCCGCAGCCGGCCGAAAGGCGGGCGTGAGGCGAACACACTGCCGCATCTGATCGCCGATATGGAGTCGATCCGCAC
CACGCTCGGGATCGAACGTTGGCTTGTGGTCGGCGGCTCGTGGGGGGCGACGCTGGCGCTGGCCTATACGCAGGCACATC
CGCAACGCGTCAGCGGCATCGTGCTGCGCGCGACCTTCCTCGGTACCCGCGCCGAGCTCGAGGAGGCGTTTCTGTCCACC
CTGCCGCGTTTCTATCCGGAACTGTCTGCTGATTTTCTGGGCATGCTGCCGGAGGCCGAGCGCGCGGCGCCGCTCGACGC
CTATTGGCGCCGAATCCTCGATCCAGACCCGGCGGTGCATGGCCCCGCGGCGCGGGCCTGGGGCGAAACCGAATCGATCA
TGTCGCAGATCGCACCGAAGCGACATCGCCTCGAGGTCTTCGACAAGAACAACAGCCGGCCGATGCCGTCGACACCGTTC
ATGGAAGCGCACTACTTCGCGCATGACTGCTTCATGCGCCCCGATCAGTTGCTGCAGGGAGCGCGCGCGCTCGCCGGCAT
TCCCGGCATCATTGTGCAGGGTCGTTACGATCTGCTGTGCCCGCCCGCCACCGCGCATCGGCTGATCGCGGCGTGGCCGG
ACGCCGAGCTCCGCATCGTCGATGCCGCCGGGCATCTTCTGTACGACCCGGGGATTCGCGACGCGGTGATCGCCGCGATC
GACGACGTCGCAGGCAGGATAACAACGTAA

Upstream 100 bases:

>100_bases
CGCAAAGGTGAGGGCAAGTTGCGCGATGCGCAACCCTGTCTCCCGCATGACGCTTCATCGGCTGCTCGCATCGGTGAAGG
TTTCCCTGTAACGAAACGTG

Downstream 100 bases:

>100_bases
AGGACATTGGCGGATGCCGCTCGCCGGACAGGGAATGCTGCTGACCTCAATGGACGTCGATCCGGCCGACGAGGCCGACT
TCAATCGCTGGTACGACCGC

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAPDAKSEIRSDDSTKAAAPLSSRMLAVGDGHEIYVETNGNADGLPAVYLHGGPGSGCQPDHRRLFDPRRFHAVLFDQRG
AGRSRPKGGREANTLPHLIADMESIRTTLGIERWLVVGGSWGATLALAYTQAHPQRVSGIVLRATFLGTRAELEEAFLST
LPRFYPELSADFLGMLPEAERAAPLDAYWRRILDPDPAVHGPAARAWGETESIMSQIAPKRHRLEVFDKNNSRPMPSTPF
MEAHYFAHDCFMRPDQLLQGARALAGIPGIIVQGRYDLLCPPATAHRLIAAWPDAELRIVDAAGHLLYDPGIRDAVIAAI
DDVAGRITT

Sequences:

>Translated_329_residues
MAPDAKSEIRSDDSTKAAAPLSSRMLAVGDGHEIYVETNGNADGLPAVYLHGGPGSGCQPDHRRLFDPRRFHAVLFDQRG
AGRSRPKGGREANTLPHLIADMESIRTTLGIERWLVVGGSWGATLALAYTQAHPQRVSGIVLRATFLGTRAELEEAFLST
LPRFYPELSADFLGMLPEAERAAPLDAYWRRILDPDPAVHGPAARAWGETESIMSQIAPKRHRLEVFDKNNSRPMPSTPF
MEAHYFAHDCFMRPDQLLQGARALAGIPGIIVQGRYDLLCPPATAHRLIAAWPDAELRIVDAAGHLLYDPGIRDAVIAAI
DDVAGRITT
>Mature_328_residues
APDAKSEIRSDDSTKAAAPLSSRMLAVGDGHEIYVETNGNADGLPAVYLHGGPGSGCQPDHRRLFDPRRFHAVLFDQRGA
GRSRPKGGREANTLPHLIADMESIRTTLGIERWLVVGGSWGATLALAYTQAHPQRVSGIVLRATFLGTRAELEEAFLSTL
PRFYPELSADFLGMLPEAERAAPLDAYWRRILDPDPAVHGPAARAWGETESIMSQIAPKRHRLEVFDKNNSRPMPSTPFM
EAHYFAHDCFMRPDQLLQGARALAGIPGIIVQGRYDLLCPPATAHRLIAAWPDAELRIVDAAGHLLYDPGIRDAVIAAID
DVAGRITT

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 35919; Mature: 35788

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDAKSEIRSDDSTKAAAPLSSRMLAVGDGHEIYVETNGNADGLPAVYLHGGPGSGCQP
CCCCCHHHHCCCCCCHHHCCHHCCEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCC
DHRRLFDPRRFHAVLFDQRGAGRSRPKGGREANTLPHLIADMESIRTTLGIERWLVVGGS
HHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCC
WGATLALAYTQAHPQRVSGIVLRATFLGTRAELEEAFLSTLPRFYPELSADFLGMLPEAE
CCCEEEEEEHHCCHHHHHHEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHH
RAAPLDAYWRRILDPDPAVHGPAARAWGETESIMSQIAPKRHRLEVFDKNNSRPMPSTPF
HCCCHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
MEAHYFAHDCFMRPDQLLQGARALAGIPGIIVQGRYDLLCPPATAHRLIAAWPDAELRIV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHEEEECCCCCEEEE
DAAGHLLYDPGIRDAVIAAIDDVAGRITT
ECCCCEEECCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
APDAKSEIRSDDSTKAAAPLSSRMLAVGDGHEIYVETNGNADGLPAVYLHGGPGSGCQP
CCCCHHHHCCCCCCHHHCCHHCCEEEECCCCEEEEEECCCCCCCCEEEEECCCCCCCCC
DHRRLFDPRRFHAVLFDQRGAGRSRPKGGREANTLPHLIADMESIRTTLGIERWLVVGGS
HHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCC
WGATLALAYTQAHPQRVSGIVLRATFLGTRAELEEAFLSTLPRFYPELSADFLGMLPEAE
CCCEEEEEEHHCCHHHHHHEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHH
RAAPLDAYWRRILDPDPAVHGPAARAWGETESIMSQIAPKRHRLEVFDKNNSRPMPSTPF
HCCCHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
MEAHYFAHDCFMRPDQLLQGARALAGIPGIIVQGRYDLLCPPATAHRLIAAWPDAELRIV
HHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCEECCCHHHHHEEEECCCCCEEEE
DAAGHLLYDPGIRDAVIAAIDDVAGRITT
ECCCCEEECCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]