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The map label for this gene is xseA [H]

Identifier: 86748982

GI number: 86748982

Start: 2123791

End: 2125407

Strand: Reverse

Name: xseA [H]

Synonym: RPB_1859

Alternate gene names: 86748982

Gene position: 2125407-2123791 (Counterclockwise)

Preceding gene: 86748992

Following gene: 86748980

Centisome position: 39.86

GC content: 70.38

Gene sequence:

>1617_bases
ATGGCCCGACTGCTCGCCCCCGAAACCCTCGCCAATGTCGGTGAATTCACCGTCTCCGAGCTGTCGCAGGCGCTGAAGCG
GACGGTGGAGGACAGCTATGGGCACGTCCGGGTGCGCGGCGAGATTTCCGGATTCCGCGGCGCGCATTCATCCGGGCACT
GCTATTTCGCCCTGAAGGACGAGAGCGCCAAGATCGAGGCGGTGATCTGGAAGGGCGTCGCGGGGCGGATGCGGTTCAAG
CCGCAGGAAGGCCTCGAGGTCATCGCCACCGGCAAGCTCACCACCTATCCCGGTTCGTCGAAATATCAGATCGTGATCGA
GGCGCTGGAGCCCGCCGGCGTCGGCGCGCTGATGGCGCTGATGGAAGAGCGCAAGCGCAAGCTCGGCGCCGAAGGGCTGT
TCGACGAAGCGCGCAAGCAATTGTTGCCGTATCTGCCCGAGGTGATCGGCGTCGTCACCTCCCCCACCGGCGCGGTGATC
CGCGACATCCTGCATCGGCTCGAAGACCGCTTCCCGCGCCGCGTGCTGGTGTGGCCGGTGAAGGTGCAGGGCGAAGGCTC
GGCCGAACAGGTCGCCGCCGCGATCCACGGCTTCAACGCGCTGCCCGAAGGCGGCCCGATCCCGCGCCCCGACCTGCTGA
TCGTCGCGCGCGGCGGCGGTTCGCTGGAGGATCTGTGGTCGTTCAACGAGGAGATCGTTGTCCGCGCCGCGGCCGAAAGC
ATGATCCCGCTGATCTCTGCGGTCGGCCACGAAACCGACGTGACGCTGATCGATTTCGCCGCAGACAAGCGCGCGCCGAC
GCCGACCGCCGCTGCCGAAATGGCGGTGCCGGTCCGCGCCGAATTGTTCGTCGAGGTGCAGAGCTACGCGCGGCGGATGA
TGCTGTGCTGGTCGCGTGGCCAGGATTCACGCCGCAACGAACTACGCGCTGCCGCCCGCGCGCTGCCCGCTGCGGGCGAA
CTGCTCGCGATCCCGCGGCAGCGGCTCGACGGCGCGGCGTCGTCCCTGCCCCGCGCGCTGCGCGCCAACACCCACGCCCA
TCACCGCCGCTACGCCAAGGCCGCGTCGGGCATCACGCTGAATGTGCTGCGCGCCCAGGTCAGCCACAGCGCGCAGCGGC
TCGGCAGCACCGGCGAGCGGCTGAAGCATTGCACCCGCGCCACGCTGCGCCATCGTCGCGACCGCTTCGAGAGTCTGGCG
ATCCGGCTGCAGGCCTCGAAGCTCGCCAACGAGCAGGCGCAGCGGATGCGGATCGCGCGCGAGCGCGAGCGGATGCTGCG
GCTCGCCGAGCGCGCCCGGCGGGCGTGGGCGACGCTGCGCGATCGCCAGCAGGCGCGCCTTGTTCAATCCGGCAAGCTGC
TCACCGCCCTGTCGTATCGCGGCGTGCTGGCACGCGGCTTCGCGCTGGTGCGCGACGCCGACGGCCATGCGCTCCATGCG
GCGGCGGCGGTCAGTGCGGGGGCGCGGCTCAGCGTCGAATTCGCCGACGGCCGCGTCGGCGTCACCGCCGATGGCGGCGG
CGCGACGCGACCGGACATTGCCAAGCCCGCCACGCCAGCAGCGAAGCCGGCGCCGAAGCGGGTGTCGAAGCCGATCGATC
AGGGCTCGCTGTTTTAG

Upstream 100 bases:

>100_bases
ACAGAGAACTCTGTAATACAGAGTATTTCGCTCAGCAAGGGTTGATTGGCGAGCGGGACGCAAATCCCTAATTTGCCGGC
GAACCAGGATACCGAATCGC

Downstream 100 bases:

>100_bases
AACTCCGGCCGGCCTGCGCTCTACCGTCCCAGCCAGTGCATCACCCGCCGCTCGGCGTCATTGCGTGCGCCCGCATCGAA
GCCGAGATGGCCTTGCGCCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MARLLAPETLANVGEFTVSELSQALKRTVEDSYGHVRVRGEISGFRGAHSSGHCYFALKDESAKIEAVIWKGVAGRMRFK
PQEGLEVIATGKLTTYPGSSKYQIVIEALEPAGVGALMALMEERKRKLGAEGLFDEARKQLLPYLPEVIGVVTSPTGAVI
RDILHRLEDRFPRRVLVWPVKVQGEGSAEQVAAAIHGFNALPEGGPIPRPDLLIVARGGGSLEDLWSFNEEIVVRAAAES
MIPLISAVGHETDVTLIDFAADKRAPTPTAAAEMAVPVRAELFVEVQSYARRMMLCWSRGQDSRRNELRAAARALPAAGE
LLAIPRQRLDGAASSLPRALRANTHAHHRRYAKAASGITLNVLRAQVSHSAQRLGSTGERLKHCTRATLRHRRDRFESLA
IRLQASKLANEQAQRMRIARERERMLRLAERARRAWATLRDRQQARLVQSGKLLTALSYRGVLARGFALVRDADGHALHA
AAAVSAGARLSVEFADGRVGVTADGGGATRPDIAKPATPAAKPAPKRVSKPIDQGSLF

Sequences:

>Translated_538_residues
MARLLAPETLANVGEFTVSELSQALKRTVEDSYGHVRVRGEISGFRGAHSSGHCYFALKDESAKIEAVIWKGVAGRMRFK
PQEGLEVIATGKLTTYPGSSKYQIVIEALEPAGVGALMALMEERKRKLGAEGLFDEARKQLLPYLPEVIGVVTSPTGAVI
RDILHRLEDRFPRRVLVWPVKVQGEGSAEQVAAAIHGFNALPEGGPIPRPDLLIVARGGGSLEDLWSFNEEIVVRAAAES
MIPLISAVGHETDVTLIDFAADKRAPTPTAAAEMAVPVRAELFVEVQSYARRMMLCWSRGQDSRRNELRAAARALPAAGE
LLAIPRQRLDGAASSLPRALRANTHAHHRRYAKAASGITLNVLRAQVSHSAQRLGSTGERLKHCTRATLRHRRDRFESLA
IRLQASKLANEQAQRMRIARERERMLRLAERARRAWATLRDRQQARLVQSGKLLTALSYRGVLARGFALVRDADGHALHA
AAAVSAGARLSVEFADGRVGVTADGGGATRPDIAKPATPAAKPAPKRVSKPIDQGSLF
>Mature_537_residues
ARLLAPETLANVGEFTVSELSQALKRTVEDSYGHVRVRGEISGFRGAHSSGHCYFALKDESAKIEAVIWKGVAGRMRFKP
QEGLEVIATGKLTTYPGSSKYQIVIEALEPAGVGALMALMEERKRKLGAEGLFDEARKQLLPYLPEVIGVVTSPTGAVIR
DILHRLEDRFPRRVLVWPVKVQGEGSAEQVAAAIHGFNALPEGGPIPRPDLLIVARGGGSLEDLWSFNEEIVVRAAAESM
IPLISAVGHETDVTLIDFAADKRAPTPTAAAEMAVPVRAELFVEVQSYARRMMLCWSRGQDSRRNELRAAARALPAAGEL
LAIPRQRLDGAASSLPRALRANTHAHHRRYAKAASGITLNVLRAQVSHSAQRLGSTGERLKHCTRATLRHRRDRFESLAI
RLQASKLANEQAQRMRIARERERMLRLAERARRAWATLRDRQQARLVQSGKLLTALSYRGVLARGFALVRDADGHALHAA
AAVSAGARLSVEFADGRVGVTADGGGATRPDIAKPATPAAKPAPKRVSKPIDQGSLF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=493, Percent_Identity=35.9026369168357, Blast_Score=251, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 58501; Mature: 58370

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLLAPETLANVGEFTVSELSQALKRTVEDSYGHVRVRGEISGFRGAHSSGHCYFALKD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEEC
ESAKIEAVIWKGVAGRMRFKPQEGLEVIATGKLTTYPGSSKYQIVIEALEPAGVGALMAL
CCCEEEEEEECCCCCCCCCCCCCCCEEEEECCEEECCCCCCEEEEEEECCCCCHHHHHHH
MEERKRKLGAEGLFDEARKQLLPYLPEVIGVVTSPTGAVIRDILHRLEDRFPRRVLVWPV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEE
KVQGEGSAEQVAAAIHGFNALPEGGPIPRPDLLIVARGGGSLEDLWSFNEEIVVRAAAES
EECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHH
MIPLISAVGHETDVTLIDFAADKRAPTPTAAAEMAVPVRAELFVEVQSYARRMMLCWSRG
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
QDSRRNELRAAARALPAAGELLAIPRQRLDGAASSLPRALRANTHAHHRRYAKAASGITL
CCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCHHHHCCHHHHCCCHHHHHHHHHHHCCCCH
NVLRAQVSHSAQRLGSTGERLKHCTRATLRHRRDRFESLAIRLQASKLANEQAQRMRIAR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERERMLRLAERARRAWATLRDRQQARLVQSGKLLTALSYRGVLARGFALVRDADGHALHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCCCEEHH
AAAVSAGARLSVEFADGRVGVTADGGGATRPDIAKPATPAAKPAPKRVSKPIDQGSLF
HHHHCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
ARLLAPETLANVGEFTVSELSQALKRTVEDSYGHVRVRGEISGFRGAHSSGHCYFALKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEEC
ESAKIEAVIWKGVAGRMRFKPQEGLEVIATGKLTTYPGSSKYQIVIEALEPAGVGALMAL
CCCEEEEEEECCCCCCCCCCCCCCCEEEEECCEEECCCCCCEEEEEEECCCCCHHHHHHH
MEERKRKLGAEGLFDEARKQLLPYLPEVIGVVTSPTGAVIRDILHRLEDRFPRRVLVWPV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEE
KVQGEGSAEQVAAAIHGFNALPEGGPIPRPDLLIVARGGGSLEDLWSFNEEIVVRAAAES
EECCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHH
MIPLISAVGHETDVTLIDFAADKRAPTPTAAAEMAVPVRAELFVEVQSYARRMMLCWSRG
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
QDSRRNELRAAARALPAAGELLAIPRQRLDGAASSLPRALRANTHAHHRRYAKAASGITL
CCHHHHHHHHHHHHCCCCCHHHHCCHHHHCCHHHHCCHHHHCCCHHHHHHHHHHHCCCCH
NVLRAQVSHSAQRLGSTGERLKHCTRATLRHRRDRFESLAIRLQASKLANEQAQRMRIAR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERERMLRLAERARRAWATLRDRQQARLVQSGKLLTALSYRGVLARGFALVRDADGHALHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCCCEEHH
AAAVSAGARLSVEFADGRVGVTADGGGATRPDIAKPATPAAKPAPKRVSKPIDQGSLF
HHHHCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]