Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 86748772

GI number: 86748772

Start: 1878552

End: 1879391

Strand: Reverse

Name: appC [H]

Synonym: RPB_1649

Alternate gene names: 86748772

Gene position: 1879391-1878552 (Counterclockwise)

Preceding gene: 86748773

Following gene: 86748771

Centisome position: 35.25

GC content: 65.48

Gene sequence:

>840_bases
ATGAAACAATTCTGGCGATTGCTGGTACGCAACCCCGGCGGGCTGATCGGGCTGATCATCCTGCTGGTCGTGATCACGGT
CGCCGTGATCGGCCCGCTGCTGTTCCCGACCTCGCCCTGGCGCATGGTGCAGCGGCCGTTTCTGCCGCCCTTCACGATGG
CCGGCCTGCCGCTGGGGACCGACGCGCTCGGTCGCGACGTGATGGCCGGGATCATCTACGGCACCCGCGTGTCGCTGCTG
GTCGGACTCGTCTCCACGCTGGTGGCGCTTGCGGTCGGCATTCCGGTCGGCGCAATGGCCGGGTATTTCGGCGGCCGTAT
CGGCGATGCCCTGATGCGCTTCACCGAATTCTTCCAGACCGTTCCGAGCTTCGCGCTTGCGATCGTGCTGGTGGCCGTGC
TGCAGCCCTCGATCGTGTCGATCATCATCGCGATCGCGATCGTCAGTTGGCCGCCGGTGGCGCGGTTGGTGCGCGGCGAG
GTGCTGTCGCTGCGGACCCGTGAATACGTTCAGGCAGCGGTCGTGACCGGGCAGACCAACAGCTGGATCATCTGGCGCGA
GATTCTCCCCAACGCGCTGTCCCCGGTCATCGTGCTGGCGTCGCTGATGGTCGCGACCGCCATCCTGCTCGAATCGTCAT
TGTCGTTTCTCGGCCTCGGCGATCCCAACCTGATGTCGTGGGGCTACATGGTCGGCGCCGGCCGCACCGTGATCCGTCAG
GCCTGGTGGATCACGGTGTTTCCGGGCATCGCCATTCTGGTCTCGGTGCTGGCGCTGAACCTGATCGGCGAAGGTCTCAA
CGATGCGCTCAATCCGCGCCTCAGCAAGGATGGACGCTGA

Upstream 100 bases:

>100_bases
TGCTCGGCGTCTTCGTGGTGTGTTCGGCGATGGTGCTGGTGTTCAACCTGATCACCGACCTGATCTACCGCTCGGTCGAT
CCCCGTATCGAGTACGCGGC

Downstream 100 bases:

>100_bases
GCATGTCCGCAGCCGCCGTATCGATCAGGAACCTGAAGCTGGCGCTGCCAGCAGGCGGCGATCGCGCGCACGCCGTCGAT
GGCGTGTCGTTCGATCTCAC

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKQFWRLLVRNPGGLIGLIILLVVITVAVIGPLLFPTSPWRMVQRPFLPPFTMAGLPLGTDALGRDVMAGIIYGTRVSLL
VGLVSTLVALAVGIPVGAMAGYFGGRIGDALMRFTEFFQTVPSFALAIVLVAVLQPSIVSIIIAIAIVSWPPVARLVRGE
VLSLRTREYVQAAVVTGQTNSWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLMSWGYMVGAGRTVIRQ
AWWITVFPGIAILVSVLALNLIGEGLNDALNPRLSKDGR

Sequences:

>Translated_279_residues
MKQFWRLLVRNPGGLIGLIILLVVITVAVIGPLLFPTSPWRMVQRPFLPPFTMAGLPLGTDALGRDVMAGIIYGTRVSLL
VGLVSTLVALAVGIPVGAMAGYFGGRIGDALMRFTEFFQTVPSFALAIVLVAVLQPSIVSIIIAIAIVSWPPVARLVRGE
VLSLRTREYVQAAVVTGQTNSWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLMSWGYMVGAGRTVIRQ
AWWITVFPGIAILVSVLALNLIGEGLNDALNPRLSKDGR
>Mature_279_residues
MKQFWRLLVRNPGGLIGLIILLVVITVAVIGPLLFPTSPWRMVQRPFLPPFTMAGLPLGTDALGRDVMAGIIYGTRVSLL
VGLVSTLVALAVGIPVGAMAGYFGGRIGDALMRFTEFFQTVPSFALAIVLVAVLQPSIVSIIIAIAIVSWPPVARLVRGE
VLSLRTREYVQAAVVTGQTNSWIIWREILPNALSPVIVLASLMVATAILLESSLSFLGLGDPNLMSWGYMVGAGRTVIRQ
AWWITVFPGIAILVSVLALNLIGEGLNDALNPRLSKDGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=243, Percent_Identity=38.6831275720165, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=33.8181818181818, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=39.5759717314488, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=37.3626373626374, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789889, Length=218, Percent_Identity=37.1559633027523, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788505, Length=236, Percent_Identity=35.5932203389831, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787549, Length=277, Percent_Identity=29.2418772563177, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29918; Mature: 29918

Theoretical pI: Translated: 11.22; Mature: 11.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]