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The map label for this gene is nadA [H]

Identifier: 86748232

GI number: 86748232

Start: 1274334

End: 1275446

Strand: Reverse

Name: nadA [H]

Synonym: RPB_1107

Alternate gene names: 86748232

Gene position: 1275446-1274334 (Counterclockwise)

Preceding gene: 86748235

Following gene: 86748231

Centisome position: 23.92

GC content: 64.69

Gene sequence:

>1113_bases
ATGCCGCTTGCTGATCTCTATGGCCCGGAAAATTTCGGCCTGCCACCGCACGCGCGTCAGTCGGCGCTCGCCCGCGCTCC
GCTGAGCGCCGTGGAGAAGGCGCGTGCCTTGCCGATGCCGGCGCTCGAATGGACGCCCGAGGTCGAGCGCGCGACCGCGC
ACCTCTATGCGCGCGTGCAGAACGTGATCCCGCCGGTCGAGTGGCCGTTCATGGCGCCCTACATCAAGGCGATCAACGAG
CTGAAGCGCGAGCGCGACGCCGTGATCCTGGCGCACAACTACCAGACCCCGGACATCTTCCATTGCGTCTCCGACATCGT
CGGCGACTCGCTGCAACTCGCCATCGAGGCCACCAAGGTCAAGGCGTCGACGATCGTCCAGTGCGGCGTGCACTTCATGG
CGGAGACCTCGAAGATCCTCAATCCGGACAAGCGCGTGCTGATCCCGGATTCGCGCGCCGGCTGTTCGCTGGCGTCCAGC
ATCACCGGCGACGATGTCCGGCTGCTGCGCGAAAAATTTCCCGGCGTGCCGGTGGTGGCTTACGTCAACACCTCGGCCGA
CGTGAAGGCGGAGGTCGACATCTGCTGCACCTCGTCGAATGCCGTGAAGGTGGTGGAGAGCCTCGGCGTCGATCGCGTGA
TCATGGTTCCTGATCAGTATCTGGCGAAATACGTCGCCTCGCAGACCAAGGTGAAGATCATCGCCTGGAAGGGCGCCTGC
GAAGTGCACGAGCGCTTCACCGGCGACGAGCTGCGCAGCTATCGCGAGGCTGACCCGAGCGTGCAGATCATCGCGCATCC
GGAATGCCCGCCGGACGTGCTGGCCGAAGCCGACTTCACCGGCTCGACTGCGCACATGATCGACTGGGTCAGGACCAGGC
ATCCGAAGCGGGTGGTGATGATCACCGAGTGCTCGATGGCCGACAACGTCCAGGCCGAGCTGCCGGACGTCGAAATGGTA
CGGCCGTGCAACCTGTGCCCGCACATGAAGCGCATCACGCTGGCGAAGATTCTCGACAGCCTGGTGTATCTGCGCGAGGA
AGTCACGGTCGACCCCGCCATCATCGCGCCGGCGCGGCGCTCGGTGGAGCGGATGATCAACCTGAACAACTGA

Upstream 100 bases:

>100_bases
CAACCAGCGTTGGAAACTGCCGGCCCGTCTTGGCCGGTTTTCTCAAAGCCAACATATGCTCAAAATGAGTACATGCTGGT
TGCGTACCAGGGAGGCCGCG

Downstream 100 bases:

>100_bases
GCCGCTTGCTGCGGCGTCTTGGACGGCGGCCTTTCCTCCTGGCGGCCGCCGTCTCCACCTCGCAATCCGCGCACGACGCT
CCGCGGACGCAGGCTGAGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPLADLYGPENFGLPPHARQSALARAPLSAVEKARALPMPALEWTPEVERATAHLYARVQNVIPPVEWPFMAPYIKAINE
LKRERDAVILAHNYQTPDIFHCVSDIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPDKRVLIPDSRAGCSLASS
ITGDDVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVKVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EVHERFTGDELRSYREADPSVQIIAHPECPPDVLAEADFTGSTAHMIDWVRTRHPKRVVMITECSMADNVQAELPDVEMV
RPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN

Sequences:

>Translated_370_residues
MPLADLYGPENFGLPPHARQSALARAPLSAVEKARALPMPALEWTPEVERATAHLYARVQNVIPPVEWPFMAPYIKAINE
LKRERDAVILAHNYQTPDIFHCVSDIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPDKRVLIPDSRAGCSLASS
ITGDDVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVKVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EVHERFTGDELRSYREADPSVQIIAHPECPPDVLAEADFTGSTAHMIDWVRTRHPKRVVMITECSMADNVQAELPDVEMV
RPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN
>Mature_369_residues
PLADLYGPENFGLPPHARQSALARAPLSAVEKARALPMPALEWTPEVERATAHLYARVQNVIPPVEWPFMAPYIKAINEL
KRERDAVILAHNYQTPDIFHCVSDIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPDKRVLIPDSRAGCSLASSI
TGDDVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVKVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGACE
VHERFTGDELRSYREADPSVQIIAHPECPPDVLAEADFTGSTAHMIDWVRTRHPKRVVMITECSMADNVQAELPDVEMVR
PCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=316, Percent_Identity=35.126582278481, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40976; Mature: 40845

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLADLYGPENFGLPPHARQSALARAPLSAVEKARALPMPALEWTPEVERATAHLYARVQ
CCCCHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
NVIPPVEWPFMAPYIKAINELKRERDAVILAHNYQTPDIFHCVSDIVGDSLQLAIEATKV
HCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHH
KASTIVQCGVHFMAETSKILNPDKRVLIPDSRAGCSLASSITGDDVRLLREKFPGVPVVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHHCCCCCEEE
YVNTSADVKAEVDICCTSSNAVKVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EECCCCCCEEEEEEEECCCCHHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCH
EVHERFTGDELRSYREADPSVQIIAHPECPPDVLAEADFTGSTAHMIDWVRTRHPKRVVM
HHHHHCCHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEE
ITECSMADNVQAELPDVEMVRPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARR
EEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHH
SVERMINLNN
HHHHHHCCCC
>Mature Secondary Structure 
PLADLYGPENFGLPPHARQSALARAPLSAVEKARALPMPALEWTPEVERATAHLYARVQ
CCCHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
NVIPPVEWPFMAPYIKAINELKRERDAVILAHNYQTPDIFHCVSDIVGDSLQLAIEATKV
HCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEHHH
KASTIVQCGVHFMAETSKILNPDKRVLIPDSRAGCSLASSITGDDVRLLREKFPGVPVVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHHCCCCCEEE
YVNTSADVKAEVDICCTSSNAVKVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EECCCCCCEEEEEEEECCCCHHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCH
EVHERFTGDELRSYREADPSVQIIAHPECPPDVLAEADFTGSTAHMIDWVRTRHPKRVVM
HHHHHCCHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCEEEE
ITECSMADNVQAELPDVEMVRPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARR
EEECCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHH
SVERMINLNN
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]