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The map label for this gene is degP [C]

Identifier: 86748139

GI number: 86748139

Start: 1163194

End: 1164159

Strand: Direct

Name: degP [C]

Synonym: RPB_1014

Alternate gene names: 86748139

Gene position: 1163194-1164159 (Clockwise)

Preceding gene: 86748135

Following gene: 86748141

Centisome position: 21.82

GC content: 68.74

Gene sequence:

>966_bases
ATGCCTTCCTTGCCCGAATGGAACGTGCCGGCCGCGATCCGGCCGCGCGCTGCGGACTTTCCGTTCGATCTCGATCGCAC
GCTGTCGGCGGTGCTCGGCGTGCACGCGATCATTCCGCCCGACGCCTTCACCGCGAATACGCTCGGCACCGAACGCGCCG
GCAACGCCGTGCTGATCGACGACGGCCTGCTGCTGACCATCGGCTATCTGATCACCGAAGCAGAGACCGTCTGGCTGCAT
CTCGGCGACGGCCGGGCGGTCGAGGGGCACGCGCTCGGCATCGATTCCGACAGCGGCTTCGGCCTGGTGCAGGCGCTCGG
CGCGATCGACCTGCCGCCGCTGCGGCTCGGCCATTCGAGCGCGGCCAAGACCGGCGATCGCGTGATCGTCGGCGGCGTCG
GCGGACGTATCCGCTCGGTCGCGGGGCGGATCGCGGCGCGGCAGCCCTTCGCCGGCTATTGGGAATATCTGATCGACGAC
GCGATCTTCACCGAGCCGTCGCACCCGAACTGGGGTGGGGCCGGGCTGATCTCCGCGACCGGCGAACTGATCGGCATCGG
CTCGCTGCAGATCGAGCGCAGCGGCAGCGACGAGCACTACAACATGATGGTGCCGATCGATCTCTTGAAGCCGGTGCTCG
GCGATCTGCGCAAATTCGGCCGGGTCGACAGACCGCCGCGGCCGTGGCTCGGGCTGTATTCGACCGAGATCGAGGACCGG
ATCGTCGTGGTCGGGATCGCGCCGAAGGGCCCCGCCGCGCGCGCCGAGCTGAAATCGGGCGATGTCATTCTCGCGGTCGC
CGGCGACAAGGTCACGAGCGAGGCGGAATTCTATCGCAAGGTCTGGGCGCTCGGCGCCGCCGGCGTCGAGGTCCCGCTGA
CGCTGTTCAGCGGCGGCGCCACCTTCGACGTCGTGCTGCATTCGGCGGACCGCGCCAAATTCCTCAAGGGACCGCGGATG
CATTGA

Upstream 100 bases:

>100_bases
GGGGCGCCGGAAGGCGGGCGCGCGCCGGCGGCGTCGGCTTGCAATTGGCTGCCGGGGTGCCGATATTTCCGGTTGGCTGA
CGCACCACGGGAGACGCCCG

Downstream 100 bases:

>100_bases
GCGGCGCTACTTCTCCGGCAGCCTGTCGTCGATTCCCTTGACGAAGACATTCATCCCGAGCACCTGGCCGTCGTCGAGAC
GGTCGCCGCCCTTGCATTCG

Product: PDZ/DHR/GLGF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MPSLPEWNVPAAIRPRAADFPFDLDRTLSAVLGVHAIIPPDAFTANTLGTERAGNAVLIDDGLLLTIGYLITEAETVWLH
LGDGRAVEGHALGIDSDSGFGLVQALGAIDLPPLRLGHSSAAKTGDRVIVGGVGGRIRSVAGRIAARQPFAGYWEYLIDD
AIFTEPSHPNWGGAGLISATGELIGIGSLQIERSGSDEHYNMMVPIDLLKPVLGDLRKFGRVDRPPRPWLGLYSTEIEDR
IVVVGIAPKGPAARAELKSGDVILAVAGDKVTSEAEFYRKVWALGAAGVEVPLTLFSGGATFDVVLHSADRAKFLKGPRM
H

Sequences:

>Translated_321_residues
MPSLPEWNVPAAIRPRAADFPFDLDRTLSAVLGVHAIIPPDAFTANTLGTERAGNAVLIDDGLLLTIGYLITEAETVWLH
LGDGRAVEGHALGIDSDSGFGLVQALGAIDLPPLRLGHSSAAKTGDRVIVGGVGGRIRSVAGRIAARQPFAGYWEYLIDD
AIFTEPSHPNWGGAGLISATGELIGIGSLQIERSGSDEHYNMMVPIDLLKPVLGDLRKFGRVDRPPRPWLGLYSTEIEDR
IVVVGIAPKGPAARAELKSGDVILAVAGDKVTSEAEFYRKVWALGAAGVEVPLTLFSGGATFDVVLHSADRAKFLKGPRM
H
>Mature_320_residues
PSLPEWNVPAAIRPRAADFPFDLDRTLSAVLGVHAIIPPDAFTANTLGTERAGNAVLIDDGLLLTIGYLITEAETVWLHL
GDGRAVEGHALGIDSDSGFGLVQALGAIDLPPLRLGHSSAAKTGDRVIVGGVGGRIRSVAGRIAARQPFAGYWEYLIDDA
IFTEPSHPNWGGAGLISATGELIGIGSLQIERSGSDEHYNMMVPIDLLKPVLGDLRKFGRVDRPPRPWLGLYSTEIEDRI
VVVGIAPKGPAARAELKSGDVILAVAGDKVTSEAEFYRKVWALGAAGVEVPLTLFSGGATFDVVLHSADRAKFLKGPRMH

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789629, Length=271, Percent_Identity=26.5682656826568, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789630, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 34060; Mature: 33929

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50106 PDZ ; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLPEWNVPAAIRPRAADFPFDLDRTLSAVLGVHAIIPPDAFTANTLGTERAGNAVLID
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEE
DGLLLTIGYLITEAETVWLHLGDGRAVEGHALGIDSDSGFGLVQALGAIDLPPLRLGHSS
CCHHHHHHHHHCCCEEEEEECCCCCEECCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
AAKTGDRVIVGGVGGRIRSVAGRIAARQPFAGYWEYLIDDAIFTEPSHPNWGGAGLISAT
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
GELIGIGSLQIERSGSDEHYNMMVPIDLLKPVLGDLRKFGRVDRPPRPWLGLYSTEIEDR
CCEEEECEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCE
IVVVGIAPKGPAARAELKSGDVILAVAGDKVTSEAEFYRKVWALGAAGVEVPLTLFSGGA
EEEEEECCCCCCCHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
TFDVVLHSADRAKFLKGPRMH
EEEEEEECCCHHHHCCCCCCC
>Mature Secondary Structure 
PSLPEWNVPAAIRPRAADFPFDLDRTLSAVLGVHAIIPPDAFTANTLGTERAGNAVLID
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCEEEEE
DGLLLTIGYLITEAETVWLHLGDGRAVEGHALGIDSDSGFGLVQALGAIDLPPLRLGHSS
CCHHHHHHHHHCCCEEEEEECCCCCEECCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
AAKTGDRVIVGGVGGRIRSVAGRIAARQPFAGYWEYLIDDAIFTEPSHPNWGGAGLISAT
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
GELIGIGSLQIERSGSDEHYNMMVPIDLLKPVLGDLRKFGRVDRPPRPWLGLYSTEIEDR
CCEEEECEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCE
IVVVGIAPKGPAARAELKSGDVILAVAGDKVTSEAEFYRKVWALGAAGVEVPLTLFSGGA
EEEEEECCCCCCCHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCC
TFDVVLHSADRAKFLKGPRMH
EEEEEEECCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]