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The map label for this gene is metA [H]

Identifier: 86748127

GI number: 86748127

Start: 1147693

End: 1148694

Strand: Direct

Name: metA [H]

Synonym: RPB_1002

Alternate gene names: 86748127

Gene position: 1147693-1148694 (Clockwise)

Preceding gene: 86748126

Following gene: 86748128

Centisome position: 21.53

GC content: 70.26

Gene sequence:

>1002_bases
ATGTCCCTGCTGTTCGACAACGCCGATCCGATCGACAGCCCGATGCTGGTCCCGAGCGGCCGGCGTGACGGGCGCAGACG
CCGCGACGCCGCCGGGCGCGACGCGGCGATCGAGATCGGGCTCGTCAACAACATGGGCGACGCCGCGCTGCGGGCCACCG
AGCGGCAGTTCGCGCGCCTGCTCGAGGCCGGCGCCGGCGATCGCCCGGTGCGGCTGCATTGCTTCGCGCTGCCCTCGGTG
CAGCGTTCGCCGGCGGCGCGTCATCGCATCGACAGCCTCTATGCCGGCATCTCCGAGCTGCGCACCATCAGGCTCGACGG
GCTGATCGTGACCGGGGCCGAACCGCGCGCCGCCACGTTGCGCGAGGAGCCGTATTGGGACGAGATGCGCGCGCTGGTCG
ACTGGGCCGAGGCCAACACCACTTCGACGATCTGGTCGTGCCTCGCCGCGCATGCGGCAGTGCTGCATCTCGACGGCATC
GAGCGGGAACGCCTGCCGAAGAAATGTTCCGGCATCTATGCCGGCGAGCGATTGCAGGACGATCCGCTGCTGATCGACCT
GCCGGCTCAGATGCAGGTGCCGCATTCGCGGCTGAACGACCTGCCGGCGGACCGGCTGGCCGCGAGCGGCTACGAGGTGC
TGACGCAGGCGCGCGACGCCGGCGTCGACGTCTTCATGCGCCGCGGGCGCAGCCGCTTCGTGTTCTTCCAGGGCCACCCC
GAATACGACATCGGCTCGCTGCAGCGCGAGTATCTGCGCGACATCGGCCGTTTCCTCACCGGCGAGCGCGAATCCTATCC
GGAGATTCCGGTCGATTATTTCGATGCCGCGACCGAGGCCGCGCTCGGCGCGTTCGGCGCGCAAGCCGAGGCCGAACCGG
AGCCCGCGCTGATTTCCCGGCTGCCGCAATTGGCGCTGCGCGCCGGCGTCGCCGACGCCATCGAGGCCACGGCCACCACG
CTGTTCCGCAACTGGCTCGACTCCCTCGCAGGCCGCTCATGA

Upstream 100 bases:

>100_bases
AACACATCGCCGACATCATCGAAGATCTCGATCAGGCGCTGGCGCAGGCCGGTGGCCGGCGCACGCAACTGATCGCGGCG
GAATAAAGCGGCGCGCCGGC

Downstream 100 bases:

>100_bases
ACATCCGCCCCGCCGCGCTGCATCGCGAATCCGCCGCCGACAGCTTCAAGGCGGCGATGCGCCACCTCGCCGGTGGCGTC
AGCATCGTCACCAGCGGGCA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSLLFDNADPIDSPMLVPSGRRDGRRRRDAAGRDAAIEIGLVNNMGDAALRATERQFARLLEAGAGDRPVRLHCFALPSV
QRSPAARHRIDSLYAGISELRTIRLDGLIVTGAEPRAATLREEPYWDEMRALVDWAEANTTSTIWSCLAAHAAVLHLDGI
ERERLPKKCSGIYAGERLQDDPLLIDLPAQMQVPHSRLNDLPADRLAASGYEVLTQARDAGVDVFMRRGRSRFVFFQGHP
EYDIGSLQREYLRDIGRFLTGERESYPEIPVDYFDAATEAALGAFGAQAEAEPEPALISRLPQLALRAGVADAIEATATT
LFRNWLDSLAGRS

Sequences:

>Translated_333_residues
MSLLFDNADPIDSPMLVPSGRRDGRRRRDAAGRDAAIEIGLVNNMGDAALRATERQFARLLEAGAGDRPVRLHCFALPSV
QRSPAARHRIDSLYAGISELRTIRLDGLIVTGAEPRAATLREEPYWDEMRALVDWAEANTTSTIWSCLAAHAAVLHLDGI
ERERLPKKCSGIYAGERLQDDPLLIDLPAQMQVPHSRLNDLPADRLAASGYEVLTQARDAGVDVFMRRGRSRFVFFQGHP
EYDIGSLQREYLRDIGRFLTGERESYPEIPVDYFDAATEAALGAFGAQAEAEPEPALISRLPQLALRAGVADAIEATATT
LFRNWLDSLAGRS
>Mature_332_residues
SLLFDNADPIDSPMLVPSGRRDGRRRRDAAGRDAAIEIGLVNNMGDAALRATERQFARLLEAGAGDRPVRLHCFALPSVQ
RSPAARHRIDSLYAGISELRTIRLDGLIVTGAEPRAATLREEPYWDEMRALVDWAEANTTSTIWSCLAAHAAVLHLDGIE
RERLPKKCSGIYAGERLQDDPLLIDLPAQMQVPHSRLNDLPADRLAASGYEVLTQARDAGVDVFMRRGRSRFVFFQGHPE
YDIGSLQREYLRDIGRFLTGERESYPEIPVDYFDAATEAALGAFGAQAEAEPEPALISRLPQLALRAGVADAIEATATTL
FRNWLDSLAGRS

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=224, Percent_Identity=29.4642857142857, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36733; Mature: 36602

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLFDNADPIDSPMLVPSGRRDGRRRRDAAGRDAAIEIGLVNNMGDAALRATERQFARL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LEAGAGDRPVRLHCFALPSVQRSPAARHRIDSLYAGISELRTIRLDGLIVTGAEPRAATL
HHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCEEEECCCCCHHHC
REEPYWDEMRALVDWAEANTTSTIWSCLAAHAAVLHLDGIERERLPKKCSGIYAGERLQD
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCHHHHCCCCCCCCCCC
DPLLIDLPAQMQVPHSRLNDLPADRLAASGYEVLTQARDAGVDVFMRRGRSRFVFFQGHP
CCEEEECCCHHCCCHHHHHCCCHHHHHHCHHHHHHHHHHCCHHHHHHCCCCEEEEEECCC
EYDIGSLQREYLRDIGRFLTGERESYPEIPVDYFDAATEAALGAFGAQAEAEPEPALISR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LPQLALRAGVADAIEATATTLFRNWLDSLAGRS
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLLFDNADPIDSPMLVPSGRRDGRRRRDAAGRDAAIEIGLVNNMGDAALRATERQFARL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
LEAGAGDRPVRLHCFALPSVQRSPAARHRIDSLYAGISELRTIRLDGLIVTGAEPRAATL
HHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCEEEECCCCCHHHC
REEPYWDEMRALVDWAEANTTSTIWSCLAAHAAVLHLDGIERERLPKKCSGIYAGERLQD
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHCHHHHCCCCCCCCCCC
DPLLIDLPAQMQVPHSRLNDLPADRLAASGYEVLTQARDAGVDVFMRRGRSRFVFFQGHP
CCEEEECCCHHCCCHHHHHCCCHHHHHHCHHHHHHHHHHCCHHHHHHCCCCEEEEEECCC
EYDIGSLQREYLRDIGRFLTGERESYPEIPVDYFDAATEAALGAFGAQAEAEPEPALISR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LPQLALRAGVADAIEATATTLFRNWLDSLAGRS
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA