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The map label for this gene is tlpA [H]

Identifier: 86747952

GI number: 86747952

Start: 940267

End: 940935

Strand: Reverse

Name: tlpA [H]

Synonym: RPB_0826

Alternate gene names: 86747952

Gene position: 940935-940267 (Counterclockwise)

Preceding gene: 86747956

Following gene: 86747951

Centisome position: 17.65

GC content: 69.21

Gene sequence:

>669_bases
ATGACCGAGACCCCGCCCGACCTCACCCCGCCGCGCCGCGCCGGCCGCCGCACCATCATTCTGGCCGCGATCGCCGTGCT
CGTGGTCGCCGGAGCAGCGGGGGTATACGGGATCGGCGGGCTGCAGCGCAATGCATCGGGCGATCCGACCTGCCGGCCGG
CGGTGGCGCTGGCGCAGCAGCTCAAGCCGCTGGCGCGCGGGGAAGTTGCGGCGGTGACGATGGCCTCGGCACCGCTGAAG
CTGCCCGACCTGATTTTCCAGGACGGCGCCGGCCAGCCGAAGAAATTGTCCGACTTCCGCGGCAAGACCCTGCTGGTGAA
CCTGTGGGCGACCTGGTGCGTGCCCTGCCGCAAGGAAATGCCCGCGCTCGACAATCTGCAGGCGAAGCTCGGCAGCCCGC
AGTTCGAGGTGGTGGCGATCAACATCGACACCCGCGACCCGGCCAAGCCTAAGAAGTTTCTCGACGACGAGAAGCTGACC
CGGCTGAACTACTTCACCGACGCCTCGGCCCGGGTGTTCCAGGACCTCAAGAGCGTCGGCCGCGCGCTGGGGATGCCGAC
CTCGGTGCTGGTCGATGGTCAGGGCTGCGAGATCGCCACCATCGCCGGCCCCGCCGAATGGGACAGTGCCGACGCGCTGG
CGCTGGTCAAGGGCGCGCTGCCAAAATAG

Upstream 100 bases:

>100_bases
CTCATAGTGTGCCGCTCACGATCATGCCCGCCTTTGCCTTTGTTCGAACCCGCCAGCAGCCGCCTGCGAGCCTGCGCAGC
TATCCGGTGTTGAGTGCCTG

Downstream 100 bases:

>100_bases
CAGCCGCGACAAAAGGACCCGGCGCCGGGTTGTCGGACAGTTCTCGCTTCGATCGTCCTGCGACCGGCCGCATGCTGCTG
CGGACGCAGACAGATCGGGG

Product: thioredoxin-like protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTETPPDLTPPRRAGRRTIILAAIAVLVVAGAAGVYGIGGLQRNASGDPTCRPAVALAQQLKPLARGEVAAVTMASAPLK
LPDLIFQDGAGQPKKLSDFRGKTLLVNLWATWCVPCRKEMPALDNLQAKLGSPQFEVVAINIDTRDPAKPKKFLDDEKLT
RLNYFTDASARVFQDLKSVGRALGMPTSVLVDGQGCEIATIAGPAEWDSADALALVKGALPK

Sequences:

>Translated_222_residues
MTETPPDLTPPRRAGRRTIILAAIAVLVVAGAAGVYGIGGLQRNASGDPTCRPAVALAQQLKPLARGEVAAVTMASAPLK
LPDLIFQDGAGQPKKLSDFRGKTLLVNLWATWCVPCRKEMPALDNLQAKLGSPQFEVVAINIDTRDPAKPKKFLDDEKLT
RLNYFTDASARVFQDLKSVGRALGMPTSVLVDGQGCEIATIAGPAEWDSADALALVKGALPK
>Mature_221_residues
TETPPDLTPPRRAGRRTIILAAIAVLVVAGAAGVYGIGGLQRNASGDPTCRPAVALAQQLKPLARGEVAAVTMASAPLKL
PDLIFQDGAGQPKKLSDFRGKTLLVNLWATWCVPCRKEMPALDNLQAKLGSPQFEVVAINIDTRDPAKPKKFLDDEKLTR
LNYFTDASARVFQDLKSVGRALGMPTSVLVDGQGCEIATIAGPAEWDSADALALVKGALPK

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 23510; Mature: 23378

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETPPDLTPPRRAGRRTIILAAIAVLVVAGAAGVYGIGGLQRNASGDPTCRPAVALAQQ
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHH
LKPLARGEVAAVTMASAPLKLPDLIFQDGAGQPKKLSDFRGKTLLVNLWATWCVPCRKEM
HHHHHCCCEEEEEECCCCCCCCHHHHCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHCC
PALDNLQAKLGSPQFEVVAINIDTRDPAKPKKFLDDEKLTRLNYFTDASARVFQDLKSVG
CCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
RALGMPTSVLVDGQGCEIATIAGPAEWDSADALALVKGALPK
HHHCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TETPPDLTPPRRAGRRTIILAAIAVLVVAGAAGVYGIGGLQRNASGDPTCRPAVALAQQ
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCHHHHHHHHH
LKPLARGEVAAVTMASAPLKLPDLIFQDGAGQPKKLSDFRGKTLLVNLWATWCVPCRKEM
HHHHHCCCEEEEEECCCCCCCCHHHHCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHCC
PALDNLQAKLGSPQFEVVAINIDTRDPAKPKKFLDDEKLTRLNYFTDASARVFQDLKSVG
CCHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
RALGMPTSVLVDGQGCEIATIAGPAEWDSADALALVKGALPK
HHHCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]