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The map label for this gene is divL [H]

Identifier: 86747750

GI number: 86747750

Start: 703696

End: 706209

Strand: Direct

Name: divL [H]

Synonym: RPB_0624

Alternate gene names: 86747750

Gene position: 703696-706209 (Clockwise)

Preceding gene: 86747749

Following gene: 86747751

Centisome position: 13.2

GC content: 68.06

Gene sequence:

>2514_bases
ATGTCGGACGTATTGGGGTCGATGCGTCGGACCTGCTTGTCGTGCACGTCGCTGGTGCGCGGCCTCGCGGGCGCTGGCCT
GGTCACGGCATCGTCGCCGGCTTTCGCGGCTGACGATCCGCTCGCCGCGCTGACCTCCTGGATCATCGTCGATCTCAACC
GCCACGAGCTGGTGACGCTGGCGATGGCGGTGTCGGTGCTCGGCTTCTCGGTGATGTCGGCGATCCTGCTGATGCGCACG
CGGCAGCGCGCCGCCGCGCAGGAGGCGCGGTTGCGCGCCGAGGTGCAGACGCTGCAGGCCGAGTCCGATCGCTTCCGCGC
CTTGCTGTTCGCCGAGCCGCAAGTGCTGATCTCGTGGTCCGCCGGCGACGACCGTCCGCAGATCAGCGGCGACATCGCGC
TGCTGCTGCCGAACGACGCCCATGGCGGACAGCCGCAACGCGTGCTCGCGTTCGGAACCTGGCTGCCGCCCGAGCCGGCG
CTGCAGATCGATCACGCCGTCGACGCGCTGCTCGACAAGGGCGAAGCCTTCCTGCTGCATCTGACGACGTCGACCGGACG
CGCGATCGAAGCGATGGGCCGCGCCGTCGGCGGCCAGGCGATCCTGCGGATTCGCGAACTCTCGGGCGTCCGTCGCGAAC
TCGCCGACATGTCGCGCCGCTTCAAGATGCTGCAGGATGAAACCGACATGCTGCGCGGCTTCGCCGATGCCGCACCCTGG
CCGATCTGGACCCGGCGCGCCTCGGGCGAACTCAACTTCGCCAATGCCGCCTATGCGCGGGCGGCCGATGCGAGCAGCCC
GGCGGATGCGGTCGGCCGCAATCTCGAACTGCTCGACAGCACCGATCGCGGCAATCTCGCGCGGGCGCTCGCCGAGGATT
CCGAATTCGCCGCGCGGCTGCCGATCGTGGTCGCCGGCGAGCGTCGTTACTTCGACGTCCGCGCGTTGCGGCTGAAGGGC
GGCAGCGCCGGCATGGCGGTGGATTCCAGCGAGGCGGCGGCGCTCGGCGCGGCGCTGGTGCGGATGGCGGAGGCGCATCG
CCGCACGCTCGATCAATTGTCGTCCGGCGTCGCGGTGTTCGACGCGCAGCGAAGGCTCGCCTTCTACAACGATTCCTATC
GCAAGCTGTGGGACCTCGACCGCACCTTCCTCGACAGCCATCCGGACGATTCGAGCGTGCTCGACCGGCTCCGCGCCGCG
CGCAAGCTGCCGGAGGAACGCGACTTCCGGGAGTGGAAGAACAGGCTGCACGAGGCCTATCGGGCGGTCGAGGCCGACAA
GGCGATCTGGTATCTGCCCGACGGCCGGGCCATCAGCATCGTCACCACGCCCAATCAGGAAGGCGGCGTCACCTATCTGT
TCGACGACGTCACCGAAAGCCTCGATCTGCAGCGCCGCTACGGCGGGCTGATCGACGTCCAGCGCGAGACCCTCGACAAT
CTCAGCGAAGCGGTCGCGGTGTTCGGCAGCAACGGCTGCGCGCAACTGTTCAACCCGGCGTTCACGCGGATGTGGAACCT
GTCGCCGGAAGCGCTCAACGACCGGCCGCACATCGAAACCGTCGAGGCCTGGTGCCGGCCGCTCTACGACGACGACGCGA
GCTGGCAGGCGCTGCGCGGCGCCATCACCGGGATCGACGACCGCAAACAGGTGGCGCTGAAGCTCGAGCGAAAGGACGGC
ACCGTGCTGTCCTGCAAGACCATGCCGCTGCCCGACGGCGCCACGATGCTGACGTTCCAGGACATCAGTGACACCGAGAA
TGTCGAGCGCGCCTTGCGCGAGCGTAACGAGGCGCTGGAGACCGCCGATCGCATCAAGATCGACTTCGTCCACCACGTCT
CCTACGAGCTGCGCTCGCCGCTGACCACGATCATCGGCTTCGCGCATCTGCTCGGCGACCCGAGCACCGGCCCGCTCAAC
GACAAGCAGTCGGAATACATCGCCTACATCACCTCGTCGACCAACGCGCTGCTGGCGATCATCAACAACATCCTCGATCT
CGCCAGCATCGACGCCGGCGCGATGACGCTCAATCTCGGGCCGATCGAGATCCGCCGCACCATCGCGGCGGCGGCGGAGG
GCATTCAGGACCGCCTCGCGCGCGACCAGATCACGCTCGACATCGACACCGATCCGGCGATCGGCGAGTTCGTCGGCGAC
GAGCGCCGGGTCGTGCAGGTGCTGTACAATCTGCTCGCCAACGCCATCGGCTTCTCGCCCAACGAGGCGACCGTGAAGCT
GGTCGTCCGCAAGAAGGGGACGAACGTGGTGTTCACCGTGACCGATGCGGGTCCGGGCATCGCGCCGGCGCTGAAGGACA
AGGTGTTCGATCTGTTCGAGAGCGATTCCCAAGGCTCGCGGCATCGCGGCCCGGGGCTCGGCCTGGCGCTGGTGCGCTCC
TTCGTCGAGCTGCACGGCGGCAAGGTCGAGGTCGATTCGGTGGTCGGGCACGGCACCTCGGTGATCTGCGAATTCCCGAT
CGAGCCGGGCGCGCAGCGCAACGCCGCCGAATGA

Upstream 100 bases:

>100_bases
GTCTGGACTCTTACCCGCGGAGTCGCGAACAGGATAATGTCCAGCGATTCGGCGACGACGCTGGCGATCCGCGATCGCGC
CGGATGGTTTGGGGCAATCC

Downstream 100 bases:

>100_bases
GCGACCCCGCGACATTCTCGGTCGCGCTCGCCAACGAGGCGGCGACGGCGCGGCTGATGGCGGACATCGCGCTGCTGATC
GGCCCGGGCGATGTCGTCAC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 837; Mature: 836

Protein sequence:

>837_residues
MSDVLGSMRRTCLSCTSLVRGLAGAGLVTASSPAFAADDPLAALTSWIIVDLNRHELVTLAMAVSVLGFSVMSAILLMRT
RQRAAAQEARLRAEVQTLQAESDRFRALLFAEPQVLISWSAGDDRPQISGDIALLLPNDAHGGQPQRVLAFGTWLPPEPA
LQIDHAVDALLDKGEAFLLHLTTSTGRAIEAMGRAVGGQAILRIRELSGVRRELADMSRRFKMLQDETDMLRGFADAAPW
PIWTRRASGELNFANAAYARAADASSPADAVGRNLELLDSTDRGNLARALAEDSEFAARLPIVVAGERRYFDVRALRLKG
GSAGMAVDSSEAAALGAALVRMAEAHRRTLDQLSSGVAVFDAQRRLAFYNDSYRKLWDLDRTFLDSHPDDSSVLDRLRAA
RKLPEERDFREWKNRLHEAYRAVEADKAIWYLPDGRAISIVTTPNQEGGVTYLFDDVTESLDLQRRYGGLIDVQRETLDN
LSEAVAVFGSNGCAQLFNPAFTRMWNLSPEALNDRPHIETVEAWCRPLYDDDASWQALRGAITGIDDRKQVALKLERKDG
TVLSCKTMPLPDGATMLTFQDISDTENVERALRERNEALETADRIKIDFVHHVSYELRSPLTTIIGFAHLLGDPSTGPLN
DKQSEYIAYITSSTNALLAIINNILDLASIDAGAMTLNLGPIEIRRTIAAAAEGIQDRLARDQITLDIDTDPAIGEFVGD
ERRVVQVLYNLLANAIGFSPNEATVKLVVRKKGTNVVFTVTDAGPGIAPALKDKVFDLFESDSQGSRHRGPGLGLALVRS
FVELHGGKVEVDSVVGHGTSVICEFPIEPGAQRNAAE

Sequences:

>Translated_837_residues
MSDVLGSMRRTCLSCTSLVRGLAGAGLVTASSPAFAADDPLAALTSWIIVDLNRHELVTLAMAVSVLGFSVMSAILLMRT
RQRAAAQEARLRAEVQTLQAESDRFRALLFAEPQVLISWSAGDDRPQISGDIALLLPNDAHGGQPQRVLAFGTWLPPEPA
LQIDHAVDALLDKGEAFLLHLTTSTGRAIEAMGRAVGGQAILRIRELSGVRRELADMSRRFKMLQDETDMLRGFADAAPW
PIWTRRASGELNFANAAYARAADASSPADAVGRNLELLDSTDRGNLARALAEDSEFAARLPIVVAGERRYFDVRALRLKG
GSAGMAVDSSEAAALGAALVRMAEAHRRTLDQLSSGVAVFDAQRRLAFYNDSYRKLWDLDRTFLDSHPDDSSVLDRLRAA
RKLPEERDFREWKNRLHEAYRAVEADKAIWYLPDGRAISIVTTPNQEGGVTYLFDDVTESLDLQRRYGGLIDVQRETLDN
LSEAVAVFGSNGCAQLFNPAFTRMWNLSPEALNDRPHIETVEAWCRPLYDDDASWQALRGAITGIDDRKQVALKLERKDG
TVLSCKTMPLPDGATMLTFQDISDTENVERALRERNEALETADRIKIDFVHHVSYELRSPLTTIIGFAHLLGDPSTGPLN
DKQSEYIAYITSSTNALLAIINNILDLASIDAGAMTLNLGPIEIRRTIAAAAEGIQDRLARDQITLDIDTDPAIGEFVGD
ERRVVQVLYNLLANAIGFSPNEATVKLVVRKKGTNVVFTVTDAGPGIAPALKDKVFDLFESDSQGSRHRGPGLGLALVRS
FVELHGGKVEVDSVVGHGTSVICEFPIEPGAQRNAAE
>Mature_836_residues
SDVLGSMRRTCLSCTSLVRGLAGAGLVTASSPAFAADDPLAALTSWIIVDLNRHELVTLAMAVSVLGFSVMSAILLMRTR
QRAAAQEARLRAEVQTLQAESDRFRALLFAEPQVLISWSAGDDRPQISGDIALLLPNDAHGGQPQRVLAFGTWLPPEPAL
QIDHAVDALLDKGEAFLLHLTTSTGRAIEAMGRAVGGQAILRIRELSGVRRELADMSRRFKMLQDETDMLRGFADAAPWP
IWTRRASGELNFANAAYARAADASSPADAVGRNLELLDSTDRGNLARALAEDSEFAARLPIVVAGERRYFDVRALRLKGG
SAGMAVDSSEAAALGAALVRMAEAHRRTLDQLSSGVAVFDAQRRLAFYNDSYRKLWDLDRTFLDSHPDDSSVLDRLRAAR
KLPEERDFREWKNRLHEAYRAVEADKAIWYLPDGRAISIVTTPNQEGGVTYLFDDVTESLDLQRRYGGLIDVQRETLDNL
SEAVAVFGSNGCAQLFNPAFTRMWNLSPEALNDRPHIETVEAWCRPLYDDDASWQALRGAITGIDDRKQVALKLERKDGT
VLSCKTMPLPDGATMLTFQDISDTENVERALRERNEALETADRIKIDFVHHVSYELRSPLTTIIGFAHLLGDPSTGPLND
KQSEYIAYITSSTNALLAIINNILDLASIDAGAMTLNLGPIEIRRTIAAAAEGIQDRLARDQITLDIDTDPAIGEFVGDE
RRVVQVLYNLLANAIGFSPNEATVKLVVRKKGTNVVFTVTDAGPGIAPALKDKVFDLFESDSQGSRHRGPGLGLALVRSF
VELHGGKVEVDSVVGHGTSVICEFPIEPGAQRNAAE

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=31.0483870967742, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=30.7116104868914, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=32.9113924050633, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=26.3598326359833, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788713, Length=278, Percent_Identity=27.3381294964029, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=30.4166666666667, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=280, Percent_Identity=24.2857142857143, Blast_Score=87, Evalue=7e-18,
Organism=Escherichia coli, GI1786912, Length=210, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=26.046511627907, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=261, Percent_Identity=26.0536398467433, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790300, Length=368, Percent_Identity=24.7282608695652, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=20.4545454545455, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=257, Percent_Identity=24.124513618677, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91457; Mature: 91325

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVLGSMRRTCLSCTSLVRGLAGAGLVTASSPAFAADDPLAALTSWIIVDLNRHELVTL
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHEEECCCHHHHHH
AMAVSVLGFSVMSAILLMRTRQRAAAQEARLRAEVQTLQAESDRFRALLFAEPQVLISWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCEEEEEEC
AGDDRPQISGDIALLLPNDAHGGQPQRVLAFGTWLPPEPALQIDHAVDALLDKGEAFLLH
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
LTTSTGRAIEAMGRAVGGQAILRIRELSGVRRELADMSRRFKMLQDETDMLRGFADAAPW
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
PIWTRRASGELNFANAAYARAADASSPADAVGRNLELLDSTDRGNLARALAEDSEFAARL
CCEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEEECCCCCCHHHHHHHCCCHHHHHC
PIVVAGERRYFDVRALRLKGGSAGMAVDSSEAAALGAALVRMAEAHRRTLDQLSSGVAVF
CEEEECCCEEEEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
DAQRRLAFYNDSYRKLWDLDRTFLDSHPDDSSVLDRLRAARKLPEERDFREWKNRLHEAY
ECHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RAVEADKAIWYLPDGRAISIVTTPNQEGGVTYLFDDVTESLDLQRRYGGLIDVQRETLDN
HHHHCCCEEEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEHHHHHHH
LSEAVAVFGSNGCAQLFNPAFTRMWNLSPEALNDRPHIETVEAWCRPLYDDDASWQALRG
HHHHHHHHCCCCHHHHHCHHHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
AITGIDDRKQVALKLERKDGTVLSCKTMPLPDGATMLTFQDISDTENVERALRERNEALE
HHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
TADRIKIDFVHHVSYELRSPLTTIIGFAHLLGDPSTGPLNDKQSEYIAYITSSTNALLAI
HHHHEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHH
INNILDLASIDAGAMTLNLGPIEIRRTIAAAAEGIQDRLARDQITLDIDTDPAIGEFVGD
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCC
ERRVVQVLYNLLANAIGFSPNEATVKLVVRKKGTNVVFTVTDAGPGIAPALKDKVFDLFE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHC
SDSQGSRHRGPGLGLALVRSFVELHGGKVEVDSVVGHGTSVICEFPIEPGAQRNAAE
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SDVLGSMRRTCLSCTSLVRGLAGAGLVTASSPAFAADDPLAALTSWIIVDLNRHELVTL
CHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHEEECCCHHHHHH
AMAVSVLGFSVMSAILLMRTRQRAAAQEARLRAEVQTLQAESDRFRALLFAEPQVLISWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCEEEEEEC
AGDDRPQISGDIALLLPNDAHGGQPQRVLAFGTWLPPEPALQIDHAVDALLDKGEAFLLH
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
LTTSTGRAIEAMGRAVGGQAILRIRELSGVRRELADMSRRFKMLQDETDMLRGFADAAPW
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
PIWTRRASGELNFANAAYARAADASSPADAVGRNLELLDSTDRGNLARALAEDSEFAARL
CCEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEEECCCCCCHHHHHHHCCCHHHHHC
PIVVAGERRYFDVRALRLKGGSAGMAVDSSEAAALGAALVRMAEAHRRTLDQLSSGVAVF
CEEEECCCEEEEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
DAQRRLAFYNDSYRKLWDLDRTFLDSHPDDSSVLDRLRAARKLPEERDFREWKNRLHEAY
ECHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RAVEADKAIWYLPDGRAISIVTTPNQEGGVTYLFDDVTESLDLQRRYGGLIDVQRETLDN
HHHHCCCEEEECCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEHHHHHHH
LSEAVAVFGSNGCAQLFNPAFTRMWNLSPEALNDRPHIETVEAWCRPLYDDDASWQALRG
HHHHHHHHCCCCHHHHHCHHHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
AITGIDDRKQVALKLERKDGTVLSCKTMPLPDGATMLTFQDISDTENVERALRERNEALE
HHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
TADRIKIDFVHHVSYELRSPLTTIIGFAHLLGDPSTGPLNDKQSEYIAYITSSTNALLAI
HHHHEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHH
INNILDLASIDAGAMTLNLGPIEIRRTIAAAAEGIQDRLARDQITLDIDTDPAIGEFVGD
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCC
ERRVVQVLYNLLANAIGFSPNEATVKLVVRKKGTNVVFTVTDAGPGIAPALKDKVFDLFE
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHC
SDSQGSRHRGPGLGLALVRSFVELHGGKVEVDSVVGHGTSVICEFPIEPGAQRNAAE
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]