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The map label for this gene is sucC [H]

Identifier: 86747406

GI number: 86747406

Start: 316530

End: 317726

Strand: Reverse

Name: sucC [H]

Synonym: RPB_0280

Alternate gene names: 86747406

Gene position: 317726-316530 (Counterclockwise)

Preceding gene: 86747407

Following gene: 86747405

Centisome position: 5.96

GC content: 63.32

Gene sequence:

>1197_bases
ATGAATATCCACGAATACCAGGCCAAAGCGGTGCTGCGCGAATTCGGCGTGCCGGTGTCGCACGGCTATCCGATCTTCAA
GGCGTCCGAGGCGGAGGCCGCCGCCACCAAGCTCGGCGGTCCGGTCTGGGTGGTGAAGAGCCAGATCCACGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAAGCCTCCGCCGGCGACAAGGGCGGCGTGCGCCTCGCCAAGTCGGTCGACGAGGTCAAG
ACTTACGCCGAGCAGATGCTGCACGCGACGCTGGTGACGGTGCAGACCGGCCCGGCCGGCAAGCAGGTCAACCGGCTGTA
CATCGAGGAAGGCTCCGAGATCGACAAGGAGTTCTATCTGTCGCTGCTGGTCGACCGCGCCACCTCGCGGATCTCCTTCG
TGGTCTCGACCGAAGGCGGCATGTCGATCGAGGACGTCGCCCATGACACCCCCGAAAAGATCGTGTCGTTCACGGTGGAT
CCGGCGACCGGCATCATGAGCCATCACGGCCGCGCCGTCGCCAACGCGCTGGGGCTGAAGGGCGACCAGGCCAAGCAGGC
CGAAAGCCTGGTGACCAAATTGTACACCGCGTTCCTCGCCAAGGACATGGAGATGCTCGAGATCAACCCGCTGGTGCTGA
CCAAGCAGGGCGATCTCAAATGCCTCGACGCCAAGATGTCATTCGACGGCAATTCGCTGTATCGCCACGCCGACATTCAG
GGCCTGCGCGACGAGAGCGAGGAAGACGCCAAGGAAATCGAGGCGTCGAAATACGACCTCAACTACGTCACCCTCGACGG
CACCATCGGCTGCATGGTCAACGGCGCTGGCCTCGCGATGGCGACGATGGACATCATCAAGCTCTACGGCATGACCCCCG
CCAACTTCCTCGACGTCGGCGGCGGCGCCAGCAAGGAGAAGGTGACCGCGGCGTTCAAGATCATCACCGCCGATCCGAAC
GTGAAGGGCATCCTGATCAACATCTTCGGCGGCATCATGAAGTGCGACATCATCGCCGAGGGCGTCGTCGCCGCGGTGAA
GGAAGTCGGCCTCGACGTGCCGCTGGTGGTGCGCCTCGAAGGCACCAATGTCGAAGCCGGCAAGAAGATCATCAAGCATT
CCGGCCTCAACGTGCTGCCCGCCGACAATCTCGACGATGCCGCGCAGAAGATCGTCAATGCCGTCAAGGGAGCCTGA

Upstream 100 bases:

>100_bases
GGACGCTAAATCAGTGTAAGCCTGCCGTGGTAAGCTCCGCCCGGCGAGGGCGCGCCACGGCGGTTCAACCGGCTGGACGC
GTTCCGGCGAGGGGCAAGCG

Downstream 100 bases:

>100_bases
GGCCGCCCCGGCCTCGCTCGCTTCCGACCAACCCGTTCGACCGCGAAAGCAACCCCGCCTATGTCCATCCTGATCGACGC
CAACACCAAAGTCATCTGCC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSVDEVK
TYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYLSLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVD
PATGIMSHHGRAVANALGLKGDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQ
GLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVGGGASKEKVTAAFKIITADPN
VKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLEGTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA

Sequences:

>Translated_398_residues
MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSVDEVK
TYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYLSLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVD
PATGIMSHHGRAVANALGLKGDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQ
GLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVGGGASKEKVTAAFKIITADPN
VKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLEGTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA
>Mature_398_residues
MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSVDEVK
TYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYLSLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVD
PATGIMSHHGRAVANALGLKGDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQ
GLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVGGGASKEKVTAAFKIITADPN
VKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLEGTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=46.1734693877551, Blast_Score=352, Evalue=3e-97,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=46.3730569948187, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=46.5753424657534, Blast_Score=313, Evalue=1e-85,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=52.3929471032746, Blast_Score=415, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17567829, Length=394, Percent_Identity=45.9390862944162, Blast_Score=347, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=45.8227848101266, Blast_Score=341, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=44.5569620253165, Blast_Score=346, Evalue=4e-96,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.8589420654912, Blast_Score=351, Evalue=6e-97,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=45.8762886597938, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=45.8762886597938, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.0154241645244, Blast_Score=343, Evalue=8e-95,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.0154241645244, Blast_Score=343, Evalue=8e-95,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42392; Mature: 42392

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
EASAGDKGGVRLAKSVDEVKTYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCCCHHHHH
SLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVDPATGIMSHHGRAVANALGLK
HHHHHHHCCEEEEEEECCCCCCHHHHHCCCCHHHEEEEECCHHHHHHHCCHHHHHHHCCC
GDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQ
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCEEEEEEECCCCCCEEEECCCC
GLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVG
CCCCCCHHHHHHHHHCEEEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPNVKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLE
CCCCCHHEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA
CCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKAVLREFGVPVSHGYPIFKASEAEAAATKLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
EASAGDKGGVRLAKSVDEVKTYAEQMLHATLVTVQTGPAGKQVNRLYIEEGSEIDKEFYL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCCCHHHHH
SLLVDRATSRISFVVSTEGGMSIEDVAHDTPEKIVSFTVDPATGIMSHHGRAVANALGLK
HHHHHHHCCEEEEEEECCCCCCHHHHHCCCCHHHEEEEECCHHHHHHHCCHHHHHHHCCC
GDQAKQAESLVTKLYTAFLAKDMEMLEINPLVLTKQGDLKCLDAKMSFDGNSLYRHADIQ
CCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCEEEEEEECCCCCCEEEECCCC
GLRDESEEDAKEIEASKYDLNYVTLDGTIGCMVNGAGLAMATMDIIKLYGMTPANFLDVG
CCCCCCHHHHHHHHHCEEEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPNVKGILINIFGGIMKCDIIAEGVVAAVKEVGLDVPLVVRLE
CCCCCHHEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GTNVEAGKKIIKHSGLNVLPADNLDDAAQKIVNAVKGA
CCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA