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The map label for this gene is comF [H]

Identifier: 86747153

GI number: 86747153

Start: 25063

End: 25827

Strand: Reverse

Name: comF [H]

Synonym: RPB_0026

Alternate gene names: 86747153

Gene position: 25827-25063 (Counterclockwise)

Preceding gene: 86747156

Following gene: 86747152

Centisome position: 0.48

GC content: 70.2

Gene sequence:

>765_bases
ATGCAGGCCGTCGGCGCGGTCCGCCGGCTGTGGTCGCGCGCGGCGCATCTGGCGCTCGATGTCGCGCTACCGACGCTGTG
CGTCGCCTGCCGCGAGCCGGTGGCGGGTGAGGGGCTGTGCCCGCAATGCTGGTCGCAGCTCTCGTTCATCGCGCCGCCTT
ATTGCGAGAAGCTCGGGATTCCGTTCGTCTATGACCCCGGGCCCGGTATCCTGTCGATGCAGGCGATCGCCGATCCGCCG
GCCTATGCCCGCGCCCGCGCCGCGGTGCGCTACGACGAGGTGGCCAAAACGCTGGTGCATGCGCTGAAATTCCACGACCG
GATCGATCTGGCGCCGACCATGGGGCGGTGGATGGCGCATGCCGGCGCGCCGCTGCTGGCCGACGCCGATCTGCTGATTC
CGGTGCCGCTGCATTGGCGGCGCGGCTTCGCCCGGCGCTACAACCAGTCCGGCGCGCTGGCGCGGGCGATCGGCCGGCAG
ACGCAATTGCCGGTGGCGATCGAGGCGCTCAAGCGGGTGCGTCCGACCGCGCATCAGATCGGACTGTCGCGGGCGGAACG
CGCCGCCAATGTGCAGGGCGCCTTCAAGGTTCCGGCCGAGCGCAAGGCCGAGGTTCAGGGGCGACGGATCGTCCTGGTCG
ACGACGTGCTGACCTCGGGCGCCACGGTCGATGCCTGCGCCCGGGCGCTGCTGCGGGCGAAGGCCCAATCGGTCGATGTG
CTGGTCTTCGCGCGGGTTGTGGACACCCTGAAATCTCCCATATAA

Upstream 100 bases:

>100_bases
CGGTTGTCAGCCTTGACGCCGGTGGGCGCGGCGCTAGCCTCCGGCCATGCAGGTGGAACCTCTCACGGCTCCTGAGGCGA
CAGCGGGTGGCGGTGGCCTG

Downstream 100 bases:

>100_bases
TCCGCATCTTGCTTCCACCGCCGAGCCCTGGAGCTGCGATGAGTGCTGCGATCGAGATCTTTACGCGTCCCGGCTGCGGC
TATTGCAGCGCCGCCAAGTC

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MQAVGAVRRLWSRAAHLALDVALPTLCVACREPVAGEGLCPQCWSQLSFIAPPYCEKLGIPFVYDPGPGILSMQAIADPP
AYARARAAVRYDEVAKTLVHALKFHDRIDLAPTMGRWMAHAGAPLLADADLLIPVPLHWRRGFARRYNQSGALARAIGRQ
TQLPVAIEALKRVRPTAHQIGLSRAERAANVQGAFKVPAERKAEVQGRRIVLVDDVLTSGATVDACARALLRAKAQSVDV
LVFARVVDTLKSPI

Sequences:

>Translated_254_residues
MQAVGAVRRLWSRAAHLALDVALPTLCVACREPVAGEGLCPQCWSQLSFIAPPYCEKLGIPFVYDPGPGILSMQAIADPP
AYARARAAVRYDEVAKTLVHALKFHDRIDLAPTMGRWMAHAGAPLLADADLLIPVPLHWRRGFARRYNQSGALARAIGRQ
TQLPVAIEALKRVRPTAHQIGLSRAERAANVQGAFKVPAERKAEVQGRRIVLVDDVLTSGATVDACARALLRAKAQSVDV
LVFARVVDTLKSPI
>Mature_254_residues
MQAVGAVRRLWSRAAHLALDVALPTLCVACREPVAGEGLCPQCWSQLSFIAPPYCEKLGIPFVYDPGPGILSMQAIADPP
AYARARAAVRYDEVAKTLVHALKFHDRIDLAPTMGRWMAHAGAPLLADADLLIPVPLHWRRGFARRYNQSGALARAIGRQ
TQLPVAIEALKRVRPTAHQIGLSRAERAANVQGAFKVPAERKAEVQGRRIVLVDDVLTSGATVDACARALLRAKAQSVDV
LVFARVVDTLKSPI

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=234, Percent_Identity=32.9059829059829, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 27528; Mature: 27528

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVGAVRRLWSRAAHLALDVALPTLCVACREPVAGEGLCPQCWSQLSFIAPPYCEKLGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHCCC
PFVYDPGPGILSMQAIADPPAYARARAAVRYDEVAKTLVHALKFHDRIDLAPTMGRWMAH
CEEECCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AGAPLLADADLLIPVPLHWRRGFARRYNQSGALARAIGRQTQLPVAIEALKRVRPTAHQI
CCCCCEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCHHHHHH
GLSRAERAANVQGAFKVPAERKAEVQGRRIVLVDDVLTSGATVDACARALLRAKAQSVDV
HHHHHHHHHCCCCCEECCCHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
LVFARVVDTLKSPI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MQAVGAVRRLWSRAAHLALDVALPTLCVACREPVAGEGLCPQCWSQLSFIAPPYCEKLGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHCCC
PFVYDPGPGILSMQAIADPPAYARARAAVRYDEVAKTLVHALKFHDRIDLAPTMGRWMAH
CEEECCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AGAPLLADADLLIPVPLHWRRGFARRYNQSGALARAIGRQTQLPVAIEALKRVRPTAHQI
CCCCCEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHCHHHHHH
GLSRAERAANVQGAFKVPAERKAEVQGRRIVLVDDVLTSGATVDACARALLRAKAQSVDV
HHHHHHHHHCCCCCEECCCHHHHHCCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
LVFARVVDTLKSPI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]