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The map label for this gene is pgk [H]

Identifier: 86609153

GI number: 86609153

Start: 1769647

End: 1770885

Strand: Reverse

Name: pgk [H]

Synonym: CYB_1693

Alternate gene names: 86609153

Gene position: 1770885-1769647 (Counterclockwise)

Preceding gene: 86609157

Following gene: 86609147

Centisome position: 58.13

GC content: 61.9

Gene sequence:

>1239_bases
ATGGCCAAACAAACACTGGGATCCCTGCTGTCATCCGGCTTTGATCTGGCCGGCAAGCGTGTGCTGGTGCGAGCCGATTT
CAATGTCCCCTTGGACGCCCAGGGCAACATTACCGATGACACCCGCATTCGGGCTGCTCTGCCCACCGTCCAGGCCCTCA
CCCAGGCAGGCGCCAAAGTGATCCTCACCAGCCACCTGGGCCGCCCCGTCAAGAAGGACAAAGAGACAGGCGCGGTTAAG
GTCGCCCGCGAGGGCAATAGCCTGGCCCCCGTGGCCACCCGTCTTTCTCAGTTGCTGGGCCAGCCGGTCGCCTTTGCCCC
CGATTGCATCGGCCCTGAGGCCGAGGCGGTAGTGAACCGCCTGGAAAACGGCCAGGTGGCCCTGCTGGAAAACGTCCGCT
TCTACCCAGAAGAGGAAGACAACGACCCGGAATTTGCCCGCAAGTTGGCCTCACTGGCCGACCTGTTCGTCAACGACGCC
TTTGGCAGTGCCCACCGCGCCCACGCCTCTACTGCCGGCGTCACCGCCTACCTCCAGCCTGCTGTGGCTGGCTACCTGGT
GGAAAGGGAGCTGCAATTCCTCTCCGGCGCCATTGAGGATCCGCGGCGCCCCTTGGCGGCCATCATCGGCGGCTCCAAAG
TCTCCACTAAGATCGGCGTCATTGAGCGGCTCCTGGAAAAAGTGGACAAACTCCTGCTGGGCGGCGGCATGATCTTTACC
TTTTACCAAGCCCAAGGGATCCAAACCGGCAAGTCTTTGGTGGAAACCGACAAGCTGGATCTGGCCCGCTCCCTGATGGA
AAAAGCCAAAGAGCGGGGGGTGGAGCTGCTGCTGCCGGTGGATGTGGTGGTAGCCGATAGGTTTGACAAAGATGCCCAGG
CCCAGACCGTTTCCATCCACGCCATCCCCGAGGATTGGATGGGCTTGGACATTGGCCCAGAATCGGTAAAAGCTTTTCAG
TCCGCCCTGCAGGGGTGCCAAACCGTGGTCTGGAATGGGCCAATGGGCGTGTTCGAATTCGACCGCTTTGCCCTGGGCAC
AGAAGCCATTGCCCGCACCCTGGCCGATCTCACTCAAGCGGGAGCCACCACCATCATCGGCGGGGGAGACTCGGTGGCTG
CCGTGGAAAAAGTGGGCCTGGCCGACAAAATGACCCATATCTCCACCGGTGGCGGAGCCAGCCTGGAGCTATTGGAAGGG
AAGGTGCTGCCCGGCATTGCCGCTCTCACAGAAGCGTAG

Upstream 100 bases:

>100_bases
ATCCCGAAGCCCATCTGTCTCACTGCCGGGATCCCAATCGCTGGTAGGATACATACGGAAGAAAAAATAAAGATTTTCTG
CAGTCCGGGGGAAAACAACG

Downstream 100 bases:

>100_bases
GTTCCTCCTTCGGGTCGCAGCCCCTCCAATCCAAAAACCAAGCCAAAAAGTAGGGGCTGGATTCAGCCCCTCCTAACTTT
AGTCGGTGTAGATCGCTGCA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAKQTLGSLLSSGFDLAGKRVLVRADFNVPLDAQGNITDDTRIRAALPTVQALTQAGAKVILTSHLGRPVKKDKETGAVK
VAREGNSLAPVATRLSQLLGQPVAFAPDCIGPEAEAVVNRLENGQVALLENVRFYPEEEDNDPEFARKLASLADLFVNDA
FGSAHRAHASTAGVTAYLQPAVAGYLVERELQFLSGAIEDPRRPLAAIIGGSKVSTKIGVIERLLEKVDKLLLGGGMIFT
FYQAQGIQTGKSLVETDKLDLARSLMEKAKERGVELLLPVDVVVADRFDKDAQAQTVSIHAIPEDWMGLDIGPESVKAFQ
SALQGCQTVVWNGPMGVFEFDRFALGTEAIARTLADLTQAGATTIIGGGDSVAAVEKVGLADKMTHISTGGGASLELLEG
KVLPGIAALTEA

Sequences:

>Translated_412_residues
MAKQTLGSLLSSGFDLAGKRVLVRADFNVPLDAQGNITDDTRIRAALPTVQALTQAGAKVILTSHLGRPVKKDKETGAVK
VAREGNSLAPVATRLSQLLGQPVAFAPDCIGPEAEAVVNRLENGQVALLENVRFYPEEEDNDPEFARKLASLADLFVNDA
FGSAHRAHASTAGVTAYLQPAVAGYLVERELQFLSGAIEDPRRPLAAIIGGSKVSTKIGVIERLLEKVDKLLLGGGMIFT
FYQAQGIQTGKSLVETDKLDLARSLMEKAKERGVELLLPVDVVVADRFDKDAQAQTVSIHAIPEDWMGLDIGPESVKAFQ
SALQGCQTVVWNGPMGVFEFDRFALGTEAIARTLADLTQAGATTIIGGGDSVAAVEKVGLADKMTHISTGGGASLELLEG
KVLPGIAALTEA
>Mature_411_residues
AKQTLGSLLSSGFDLAGKRVLVRADFNVPLDAQGNITDDTRIRAALPTVQALTQAGAKVILTSHLGRPVKKDKETGAVKV
AREGNSLAPVATRLSQLLGQPVAFAPDCIGPEAEAVVNRLENGQVALLENVRFYPEEEDNDPEFARKLASLADLFVNDAF
GSAHRAHASTAGVTAYLQPAVAGYLVERELQFLSGAIEDPRRPLAAIIGGSKVSTKIGVIERLLEKVDKLLLGGGMIFTF
YQAQGIQTGKSLVETDKLDLARSLMEKAKERGVELLLPVDVVVADRFDKDAQAQTVSIHAIPEDWMGLDIGPESVKAFQS
ALQGCQTVVWNGPMGVFEFDRFALGTEAIARTLADLTQAGATTIIGGGDSVAAVEKVGLADKMTHISTGGGASLELLEGK
VLPGIAALTEA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=416, Percent_Identity=44.4711538461538, Blast_Score=349, Evalue=3e-96,
Organism=Homo sapiens, GI31543397, Length=416, Percent_Identity=43.0288461538462, Blast_Score=338, Evalue=4e-93,
Organism=Escherichia coli, GI1789294, Length=398, Percent_Identity=44.4723618090452, Blast_Score=310, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17508823, Length=428, Percent_Identity=47.4299065420561, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319857, Length=425, Percent_Identity=46.8235294117647, Blast_Score=365, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24581203, Length=418, Percent_Identity=44.9760765550239, Blast_Score=338, Evalue=3e-93,
Organism=Drosophila melanogaster, GI17136394, Length=422, Percent_Identity=45.7345971563981, Blast_Score=337, Evalue=1e-92,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 43532; Mature: 43401

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQTLGSLLSSGFDLAGKRVLVRADFNVPLDAQGNITDDTRIRAALPTVQALTQAGAKV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
ILTSHLGRPVKKDKETGAVKVAREGNSLAPVATRLSQLLGQPVAFAPDCIGPEAEAVVNR
EEEHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LENGQVALLENVRFYPEEEDNDPEFARKLASLADLFVNDAFGSAHRAHASTAGVTAYLQP
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHH
AVAGYLVERELQFLSGAIEDPRRPLAAIIGGSKVSTKIGVIERLLEKVDKLLLGGGMIFT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FYQAQGIQTGKSLVETDKLDLARSLMEKAKERGVELLLPVDVVVADRFDKDAQAQTVSIH
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCEEEEEE
AIPEDWMGLDIGPESVKAFQSALQGCQTVVWNGPMGVFEFDRFALGTEAIARTLADLTQA
ECCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GATTIIGGGDSVAAVEKVGLADKMTHISTGGGASLELLEGKVLPGIAALTEA
CCEEEECCCCCHHHHHHHCCHHHHHEECCCCCCEEEEECCCCCCCHHHHCCC
>Mature Secondary Structure 
AKQTLGSLLSSGFDLAGKRVLVRADFNVPLDAQGNITDDTRIRAALPTVQALTQAGAKV
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
ILTSHLGRPVKKDKETGAVKVAREGNSLAPVATRLSQLLGQPVAFAPDCIGPEAEAVVNR
EEEHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LENGQVALLENVRFYPEEEDNDPEFARKLASLADLFVNDAFGSAHRAHASTAGVTAYLQP
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHH
AVAGYLVERELQFLSGAIEDPRRPLAAIIGGSKVSTKIGVIERLLEKVDKLLLGGGMIFT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
FYQAQGIQTGKSLVETDKLDLARSLMEKAKERGVELLLPVDVVVADRFDKDAQAQTVSIH
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCEEEEEE
AIPEDWMGLDIGPESVKAFQSALQGCQTVVWNGPMGVFEFDRFALGTEAIARTLADLTQA
ECCCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GATTIIGGGDSVAAVEKVGLADKMTHISTGGGASLELLEGKVLPGIAALTEA
CCEEEECCCCCHHHHHHHCCHHHHHEECCCCCCEEEEECCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA