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The map label for this gene is mrdB [H]

Identifier: 86609109

GI number: 86609109

Start: 1721267

End: 1722577

Strand: Reverse

Name: mrdB [H]

Synonym: CYB_1649

Alternate gene names: 86609109

Gene position: 1722577-1721267 (Counterclockwise)

Preceding gene: 86609110

Following gene: 86609108

Centisome position: 56.54

GC content: 58.2

Gene sequence:

>1311_bases
TTGCTGGGCAACGTTGACCCAAAGGTGTCTTCTCAGCCTAGGTGGAAAAAGCTTCTGCGGCAGATCTTGGCTCCTTGGCG
CGAGTTCGATGGCATGTTGCTGGCCACGGTGCTGGCCTTGACAGGCATCGGCATTCTTGCCATCCGCAGCGCAGTCTGGG
AGCGGCCCATCAGCCACTATTGGCTGCAGCAGTTGATCATGGCCGGGATCAGCCTGGTGTTTTTGGGAATGGTAGCCCGG
ATCCCGTATGAGCGGCTTTTGCGCTGGCACTGGTTCACCTACTTCCTGACCTTGGCAGGTTTAATTGCAGTGCTCTTTTT
CGGCACGGCGGGGGGAGGGGCGGAGCGCTGGCTCTCCATCGCTGGCTTTCAGGTGCAGCCTTCTGAGTTTGCCAAGCTGG
GGGTAATTGTTACCCTGGCTGCTCTCCTGCACCACTGGCCGATCAAGTACTTCAGCCAGATTTGGGTGGCCGTTGCCGTC
ATTGCTCCTCCCTGGATCTTGATTTTCCTGCAGCCCAACCTGGGCACTGCCCTGGTGTTTGTGGTGATTGTGCTGGTCAT
GCTCTACTGGGCCGGAGCCAAGGGCAGTTGGATCCTCTTGCTTTTGTCGCCGGGGGTGGGAGCCATTCTCTATGGCTTAC
ACACTCGCCCAGAGCTGAGCTGGATGCTTTGGGTTTGGCTGCTCTGGTGTCTGGGAATGGCGGGGTTGGCTGCTTGGCGT
CTCCCCTGGCAGTGGACGGGGGCCGTAACTTTTGGGGTAATCAACCTGCTCTCGGGGCAGTTGGGTCAGCTAGCTTGGCA
CCTTCTCAAGCCCTATCAGCGGCGGCGGCTGGAGATTTTTATCGATCCCATGCAAGAGCCCTGGGGAGCCGGCTATCACC
TCATTCAATCCCGCATTGCCATCGGAGCCGGCGGCCTCTGGGGCCGCGGTATCCAGCAGGGCACCCAAACCCAGCTGGAC
TTCATCCCCGAACAGCACACGGATTTTATTTTCTCCGCCATTGGGGAAGAGATGGGCTTTGTGGGCACCCTGACGGTGCT
GATCCTGTTCTGGATCCTGTGTGCGCGGCTGATCTGGATTGCCCAAGGGGCCAAGGACAATTTTGGATCCCTGATTGCCA
TTGGGGTGCTGGCGATGATCCTCTTTCAGGCGGTGGTGAACATCAGCATGACCATCGGCCTGGCCCCGATTACCGGCTTG
CCTTTGCCTTTTCTAAGTTATGGCCGCTCGGCTCTACTGACCAATTTTCTGGCCATTGGCTTGGTGGAATCGGTGGTGAT
GCACCGCCAGCGTACTAGTCTTTTCAAGTAG

Upstream 100 bases:

>100_bases
CTGGGAATAGCTCCCCCAGTGGGAGAGGGGTCGAGAGTGAGCCAGTGGGGCAAGGGGCATGTCAAACTGGTGCTGGCCTT
GCTTTGGAGGATGGGGTCTA

Downstream 100 bases:

>100_bases
GCAGGCTCAATTTGCCTCCAGCGGGTTTGGCCTCAACAAGGGGAAGCTGCTGCCAGCGTTGGGCAACACTGGCCAAGGAT
CTTAAGATAGGAACACGGAG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLGNVDPKVSSQPRWKKLLRQILAPWREFDGMLLATVLALTGIGILAIRSAVWERPISHYWLQQLIMAGISLVFLGMVAR
IPYERLLRWHWFTYFLTLAGLIAVLFFGTAGGGAERWLSIAGFQVQPSEFAKLGVIVTLAALLHHWPIKYFSQIWVAVAV
IAPPWILIFLQPNLGTALVFVVIVLVMLYWAGAKGSWILLLLSPGVGAILYGLHTRPELSWMLWVWLLWCLGMAGLAAWR
LPWQWTGAVTFGVINLLSGQLGQLAWHLLKPYQRRRLEIFIDPMQEPWGAGYHLIQSRIAIGAGGLWGRGIQQGTQTQLD
FIPEQHTDFIFSAIGEEMGFVGTLTVLILFWILCARLIWIAQGAKDNFGSLIAIGVLAMILFQAVVNISMTIGLAPITGL
PLPFLSYGRSALLTNFLAIGLVESVVMHRQRTSLFK

Sequences:

>Translated_436_residues
MLGNVDPKVSSQPRWKKLLRQILAPWREFDGMLLATVLALTGIGILAIRSAVWERPISHYWLQQLIMAGISLVFLGMVAR
IPYERLLRWHWFTYFLTLAGLIAVLFFGTAGGGAERWLSIAGFQVQPSEFAKLGVIVTLAALLHHWPIKYFSQIWVAVAV
IAPPWILIFLQPNLGTALVFVVIVLVMLYWAGAKGSWILLLLSPGVGAILYGLHTRPELSWMLWVWLLWCLGMAGLAAWR
LPWQWTGAVTFGVINLLSGQLGQLAWHLLKPYQRRRLEIFIDPMQEPWGAGYHLIQSRIAIGAGGLWGRGIQQGTQTQLD
FIPEQHTDFIFSAIGEEMGFVGTLTVLILFWILCARLIWIAQGAKDNFGSLIAIGVLAMILFQAVVNISMTIGLAPITGL
PLPFLSYGRSALLTNFLAIGLVESVVMHRQRTSLFK
>Mature_436_residues
MLGNVDPKVSSQPRWKKLLRQILAPWREFDGMLLATVLALTGIGILAIRSAVWERPISHYWLQQLIMAGISLVFLGMVAR
IPYERLLRWHWFTYFLTLAGLIAVLFFGTAGGGAERWLSIAGFQVQPSEFAKLGVIVTLAALLHHWPIKYFSQIWVAVAV
IAPPWILIFLQPNLGTALVFVVIVLVMLYWAGAKGSWILLLLSPGVGAILYGLHTRPELSWMLWVWLLWCLGMAGLAAWR
LPWQWTGAVTFGVINLLSGQLGQLAWHLLKPYQRRRLEIFIDPMQEPWGAGYHLIQSRIAIGAGGLWGRGIQQGTQTQLD
FIPEQHTDFIFSAIGEEMGFVGTLTVLILFWILCARLIWIAQGAKDNFGSLIAIGVLAMILFQAVVNISMTIGLAPITGL
PLPFLSYGRSALLTNFLAIGLVESVVMHRQRTSLFK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=367, Percent_Identity=34.3324250681199, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786277, Length=346, Percent_Identity=29.4797687861272, Blast_Score=132, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 48700; Mature: 48700

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGNVDPKVSSQPRWKKLLRQILAPWREFDGMLLATVLALTGIGILAIRSAVWERPISHY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
WLQQLIMAGISLVFLGMVARIPYERLLRWHWFTYFLTLAGLIAVLFFGTAGGGAERWLSI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AGFQVQPSEFAKLGVIVTLAALLHHWPIKYFSQIWVAVAVIAPPWILIFLQPNLGTALVF
CCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
VVIVLVMLYWAGAKGSWILLLLSPGVGAILYGLHTRPELSWMLWVWLLWCLGMAGLAAWR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LPWQWTGAVTFGVINLLSGQLGQLAWHLLKPYQRRRLEIFIDPMQEPWGAGYHLIQSRIA
CCCEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCHHHHHHHHHH
IGAGGLWGRGIQQGTQTQLDFIPEQHTDFIFSAIGEEMGFVGTLTVLILFWILCARLIWI
HCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGAKDNFGSLIAIGVLAMILFQAVVNISMTIGLAPITGLPLPFLSYGRSALLTNFLAIG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHHHHHHH
LVESVVMHRQRTSLFK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGNVDPKVSSQPRWKKLLRQILAPWREFDGMLLATVLALTGIGILAIRSAVWERPISHY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
WLQQLIMAGISLVFLGMVARIPYERLLRWHWFTYFLTLAGLIAVLFFGTAGGGAERWLSI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AGFQVQPSEFAKLGVIVTLAALLHHWPIKYFSQIWVAVAVIAPPWILIFLQPNLGTALVF
CCCEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
VVIVLVMLYWAGAKGSWILLLLSPGVGAILYGLHTRPELSWMLWVWLLWCLGMAGLAAWR
HHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LPWQWTGAVTFGVINLLSGQLGQLAWHLLKPYQRRRLEIFIDPMQEPWGAGYHLIQSRIA
CCCEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHCCEEEEECCCCCCCCCHHHHHHHHHH
IGAGGLWGRGIQQGTQTQLDFIPEQHTDFIFSAIGEEMGFVGTLTVLILFWILCARLIWI
HCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGAKDNFGSLIAIGVLAMILFQAVVNISMTIGLAPITGLPLPFLSYGRSALLTNFLAIG
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHHHHHHH
LVESVVMHRQRTSLFK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]