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The map label for this gene is phoR [H]

Identifier: 86609101

GI number: 86609101

Start: 1706804

End: 1708045

Strand: Reverse

Name: phoR [H]

Synonym: CYB_1639

Alternate gene names: 86609101

Gene position: 1708045-1706804 (Counterclockwise)

Preceding gene: 86609102

Following gene: 86609098

Centisome position: 56.06

GC content: 60.23

Gene sequence:

>1242_bases
ATGCTGAGGCCTAATCCCCATCCTCCAGCCGGCTCGTCGCCGGTAGGCCCTCTTCCCGGGGCACAGCCGGGATCCCCCTC
GCCTGAAAAGAAGCCGTTGGTGTTGGTGGTGGACGATGAGCGCAGCCAGCGGCTCTTGGTTTGCTACGCCCTTGAGCGAG
AAGGCTACCAAGTCCTGGAAGCCAGCAGCGGCGAGGCTTGCTTGCAGCTAGCCGCTCAACACCCAGTGGATATGGTGTTG
CTGGATGCGGTCATGCCAGATTTGGATGGGTTTGAGTGCTGTCGCCGCCTCCATGCTCAAAACTCGGATCTGCCCATTCT
CATCGTCACGGCGCTGGAAGATGAGTCCTGCGTGGATGAAGCCTTTGCTGCCGGGGCCAGCGATTACATTTCCAAACCCA
TTCGTTGGGCGGTTTTGAAGCGGCGTATCCGTCACCTGATCCAGGCCAGCCAAGCCCAACGCCACCTGCGGGAACTCAAC
CAAGCCCTAGAAGCCAAAGTGCAGGAACGTACCGCCCAGTTGGCCTGCCAGGTACAGGACTTGCAGCAGCTCAGCCGCCT
TAAGGATAGCTTTCTGGCCAGCGTTTCCCACGAGCTGCGCACTCCCCTCACCAAGATCAAGCTGGCCCTGGAGCTATTGG
GCCGCTCCCCTCTAGACGAGAAGCAGCGCCAATACCACCGCATTGCCCTGGAAGAATGTCAAGCTGAAATCGAGCTAATC
AACAGATTGCTGGATCTGCAGGGCCTGGAAGCCAAGGAGTTGGGCTCTGCGGCTGCCGCCATCGATCTCCACAGCCTTTG
CACAAGCCTGCTCGACGGGGTGCGAGAACGGGCTCAAGCCCGGCAACTGAAGCTGGAGATGGCAGAGCTGACCTCATTCC
CGGCAGTGCTCTACAGCTACCCGCAGCGGCTAACCCTGATCCTGAAGGAACTGCTGGAAAATGCCTGCAAGTTTACCCAG
CCGGGCGGAACCCTCCGCTTGGAGGTGCAAGCCTTTCCCGGTGGGGTTGAGCTAAGGATTGGCAACACCGCCCAAATTGA
GCCTGACCACCTGCCCCACCTTTTCGAGCGCTTTTACCGGGTGCCTTCTGAGGATCCCTGGGCGCAGCCGGGCAGCGGCC
TTGGACTGGCCTTGGTGAAGCAGTGGGTGGAGTATCTGCAGGGCCAAGTCCGGGTCACCAGCCAGAAGGGATGGACTTGG
TTTGTCCTTTGGCTGCCCAGCCTAGAGCCCTCCAACCGTTGA

Upstream 100 bases:

>100_bases
ATAGAGCAAGCCGTGCAGAAGCTGGAGGTGGCATATCGGCAAGTTACCCTCAGTCTCTCCTCCTGAGTGCAGAGCCTTTC
TCCCTCCCCTCTCAATGCCT

Downstream 100 bases:

>100_bases
CGCCCAAAGGCGGGTGGGAGGCAGCGATTGAGACTTTAGTGACCAACGACAGCAGCAGTCTCAGCAGTGGCAAAGGAGGT
GCCACACCCACAGCTAGCTA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MLRPNPHPPAGSSPVGPLPGAQPGSPSPEKKPLVLVVDDERSQRLLVCYALEREGYQVLEASSGEACLQLAAQHPVDMVL
LDAVMPDLDGFECCRRLHAQNSDLPILIVTALEDESCVDEAFAAGASDYISKPIRWAVLKRRIRHLIQASQAQRHLRELN
QALEAKVQERTAQLACQVQDLQQLSRLKDSFLASVSHELRTPLTKIKLALELLGRSPLDEKQRQYHRIALEECQAEIELI
NRLLDLQGLEAKELGSAAAAIDLHSLCTSLLDGVRERAQARQLKLEMAELTSFPAVLYSYPQRLTLILKELLENACKFTQ
PGGTLRLEVQAFPGGVELRIGNTAQIEPDHLPHLFERFYRVPSEDPWAQPGSGLGLALVKQWVEYLQGQVRVTSQKGWTW
FVLWLPSLEPSNR

Sequences:

>Translated_413_residues
MLRPNPHPPAGSSPVGPLPGAQPGSPSPEKKPLVLVVDDERSQRLLVCYALEREGYQVLEASSGEACLQLAAQHPVDMVL
LDAVMPDLDGFECCRRLHAQNSDLPILIVTALEDESCVDEAFAAGASDYISKPIRWAVLKRRIRHLIQASQAQRHLRELN
QALEAKVQERTAQLACQVQDLQQLSRLKDSFLASVSHELRTPLTKIKLALELLGRSPLDEKQRQYHRIALEECQAEIELI
NRLLDLQGLEAKELGSAAAAIDLHSLCTSLLDGVRERAQARQLKLEMAELTSFPAVLYSYPQRLTLILKELLENACKFTQ
PGGTLRLEVQAFPGGVELRIGNTAQIEPDHLPHLFERFYRVPSEDPWAQPGSGLGLALVKQWVEYLQGQVRVTSQKGWTW
FVLWLPSLEPSNR
>Mature_413_residues
MLRPNPHPPAGSSPVGPLPGAQPGSPSPEKKPLVLVVDDERSQRLLVCYALEREGYQVLEASSGEACLQLAAQHPVDMVL
LDAVMPDLDGFECCRRLHAQNSDLPILIVTALEDESCVDEAFAAGASDYISKPIRWAVLKRRIRHLIQASQAQRHLRELN
QALEAKVQERTAQLACQVQDLQQLSRLKDSFLASVSHELRTPLTKIKLALELLGRSPLDEKQRQYHRIALEECQAEIELI
NRLLDLQGLEAKELGSAAAAIDLHSLCTSLLDGVRERAQARQLKLEMAELTSFPAVLYSYPQRLTLILKELLENACKFTQ
PGGTLRLEVQAFPGGVELRIGNTAQIEPDHLPHLFERFYRVPSEDPWAQPGSGLGLALVKQWVEYLQGQVRVTSQKGWTW
FVLWLPSLEPSNR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=32.034632034632, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=30.8370044052863, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=29.9539170506912, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1789149, Length=305, Percent_Identity=26.8852459016393, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=276, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=27.4590163934426, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=220, Percent_Identity=26.8181818181818, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=30.8823529411765, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=28.0701754385965, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786911, Length=111, Percent_Identity=39.6396396396396, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789809, Length=115, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=31.9327731092437, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790860, Length=115, Percent_Identity=33.9130434782609, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788394, Length=134, Percent_Identity=33.5820895522388, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=33.6206896551724, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790863, Length=136, Percent_Identity=27.2058823529412, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46117; Mature: 46117

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPNPHPPAGSSPVGPLPGAQPGSPSPEKKPLVLVVDDERSQRLLVCYALEREGYQVLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEE
ASSGEACLQLAAQHPVDMVLLDAVMPDLDGFECCRRLHAQNSDLPILIVTALEDESCVDE
CCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
AFAAGASDYISKPIRWAVLKRRIRHLIQASQAQRHLRELNQALEAKVQERTAQLACQVQD
HHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQLSRLKDSFLASVSHELRTPLTKIKLALELLGRSPLDEKQRQYHRIALEECQAEIELI
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NRLLDLQGLEAKELGSAAAAIDLHSLCTSLLDGVRERAQARQLKLEMAELTSFPAVLYSY
HHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQRLTLILKELLENACKFTQPGGTLRLEVQAFPGGVELRIGNTAQIEPDHLPHLFERFYR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHC
VPSEDPWAQPGSGLGLALVKQWVEYLQGQVRVTSQKGWTWFVLWLPSLEPSNR
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MLRPNPHPPAGSSPVGPLPGAQPGSPSPEKKPLVLVVDDERSQRLLVCYALEREGYQVLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCCCEEEE
ASSGEACLQLAAQHPVDMVLLDAVMPDLDGFECCRRLHAQNSDLPILIVTALEDESCVDE
CCCCHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
AFAAGASDYISKPIRWAVLKRRIRHLIQASQAQRHLRELNQALEAKVQERTAQLACQVQD
HHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQQLSRLKDSFLASVSHELRTPLTKIKLALELLGRSPLDEKQRQYHRIALEECQAEIELI
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
NRLLDLQGLEAKELGSAAAAIDLHSLCTSLLDGVRERAQARQLKLEMAELTSFPAVLYSY
HHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PQRLTLILKELLENACKFTQPGGTLRLEVQAFPGGVELRIGNTAQIEPDHLPHLFERFYR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHC
VPSEDPWAQPGSGLGLALVKQWVEYLQGQVRVTSQKGWTWFVLWLPSLEPSNR
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]