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The map label for this gene is rnz [H]

Identifier: 86609098

GI number: 86609098

Start: 1705315

End: 1706301

Strand: Reverse

Name: rnz [H]

Synonym: CYB_1636

Alternate gene names: 86609098

Gene position: 1706301-1705315 (Counterclockwise)

Preceding gene: 86609101

Following gene: 86609097

Centisome position: 56.01

GC content: 63.02

Gene sequence:

>987_bases
GTGACAGATCCCAACGCCATTCGGATCACCTTTTTGGGCACCAGCTCCGGCATGCCCACCCGCCAGCGCAATGTCTCTGG
GGTGGCGGTGCAGTTTCCCCAGCGGTCGGAATGGTGGCTGTTCGATTGTGGCGAGGGCACCCAGCACCAGTTGCTGCGCC
TAGACGAGCTGCGCCCCAGCCAGTTGCGCCGCATTTTCATCACCCACATGCACGGGGATCACATCTACGGCCTGCCGGGG
CTGTTGGCCTCCTGTGGCTTGGGCAGCACCCCTGAGCACATCGATATCTACGGCCCACCAGGTCTGGAAGAGTACCTGAA
GGCCGTGTTGCGCTACAGCGAGACCCGGATCCCCTACGGCTTCCGCGTTCACACCGTCGAAACCGGTCTCATCCTGCAAG
AGCCGGAATACTCCGTCTTCTGCGCGCCCTTGGATCACCGGGTGCCCGCCTTCGGCTACCGCGTGGTGGAACAGGATCGG
CCAGGCAGCTTTAATGTGGCCAAAGCCCAGGCCGATGGGATCCCCTTTGGCCCTCTGTATGGGCAGCTCAAGGCCGGCCA
ATCCATCATCTGGCAGGGCCGCTGCTTTCACGGACGGGATTATGTCGGGGATCCCATTCCGGGCCGCAAATTCTCCTACT
GCACCGACACGATTTTCTGCCGCAATGCTGTTGATCTCTCCCGGGCTGCGGATCTGGTCATCCACGAGGCTACCTACGCT
CAGGCTGACTTGGAGCTGGCCCGCCGCTCTAAGCATTCCACCGCCGCCATGGCCGCCCAAGTGGCCGCCGAAGCCAAGGC
CCAAGCTTTGATCCTCACCCACTTCAGCCCCCGCTACACCCCAGAGGCCCCCATTACCTTGGAAGACCTGCTGGCAGAAG
CTCAGGCCATTTTTCCCAATACCCTGCTGGCCCGCGATCGGCTGACCTACGAGATCCCCCGTCGCAGCCCGTCCCCTCTG
CCGGTGGGTGTGGGCTTGCCTCGCTAG

Upstream 100 bases:

>100_bases
CTCAAGGGTACGTTCTACTCCCCATCCTATCAAGGGTTTTTTCTCGGCCAGCGAGAGCAATTGGTAAGCTAGGGATCCCA
ATCCTTGAGGTTTTGCCCCT

Downstream 100 bases:

>100_bases
AATGGTAGAACTGACTGTCTCAACCGGCAATGACGGATCCCAGACCTTACCCCGAACGTCCCCCATTTCCAGAGCGGCCC
AAAACCGAACAACTGGATCA

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTDPNAIRITFLGTSSGMPTRQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLLRLDELRPSQLRRIFITHMHGDHIYGLPG
LLASCGLGSTPEHIDIYGPPGLEEYLKAVLRYSETRIPYGFRVHTVETGLILQEPEYSVFCAPLDHRVPAFGYRVVEQDR
PGSFNVAKAQADGIPFGPLYGQLKAGQSIIWQGRCFHGRDYVGDPIPGRKFSYCTDTIFCRNAVDLSRAADLVIHEATYA
QADLELARRSKHSTAAMAAQVAAEAKAQALILTHFSPRYTPEAPITLEDLLAEAQAIFPNTLLARDRLTYEIPRRSPSPL
PVGVGLPR

Sequences:

>Translated_328_residues
MTDPNAIRITFLGTSSGMPTRQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLLRLDELRPSQLRRIFITHMHGDHIYGLPG
LLASCGLGSTPEHIDIYGPPGLEEYLKAVLRYSETRIPYGFRVHTVETGLILQEPEYSVFCAPLDHRVPAFGYRVVEQDR
PGSFNVAKAQADGIPFGPLYGQLKAGQSIIWQGRCFHGRDYVGDPIPGRKFSYCTDTIFCRNAVDLSRAADLVIHEATYA
QADLELARRSKHSTAAMAAQVAAEAKAQALILTHFSPRYTPEAPITLEDLLAEAQAIFPNTLLARDRLTYEIPRRSPSPL
PVGVGLPR
>Mature_327_residues
TDPNAIRITFLGTSSGMPTRQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLLRLDELRPSQLRRIFITHMHGDHIYGLPGL
LASCGLGSTPEHIDIYGPPGLEEYLKAVLRYSETRIPYGFRVHTVETGLILQEPEYSVFCAPLDHRVPAFGYRVVEQDRP
GSFNVAKAQADGIPFGPLYGQLKAGQSIIWQGRCFHGRDYVGDPIPGRKFSYCTDTIFCRNAVDLSRAADLVIHEATYAQ
ADLELARRSKHSTAAMAAQVAAEAKAQALILTHFSPRYTPEAPITLEDLLAEAQAIFPNTLLARDRLTYEIPRRSPSPLP
VGVGLPR

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=365, Percent_Identity=33.972602739726, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI260166619, Length=219, Percent_Identity=30.5936073059361, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082078, Length=309, Percent_Identity=40.7766990291262, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 36453; Mature: 36322

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPNAIRITFLGTSSGMPTRQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLLRLDELRPS
CCCCCEEEEEEEECCCCCCCHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCCHH
QLRRIFITHMHGDHIYGLPGLLASCGLGSTPEHIDIYGPPGLEEYLKAVLRYSETRIPYG
HEEEEEEEEECCCEEECCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
FRVHTVETGLILQEPEYSVFCAPLDHRVPAFGYRVVEQDRPGSFNVAKAQADGIPFGPLY
EEEEEEECCEEEECCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCH
GQLKAGQSIIWQGRCFHGRDYVGDPIPGRKFSYCTDTIFCRNAVDLSRAADLVIHEATYA
HHHHCCCEEEEECEEECCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHEEEEECHHH
QADLELARRSKHSTAAMAAQVAAEAKAQALILTHFSPRYTPEAPITLEDLLAEAQAIFPN
HHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLLARDRLTYEIPRRSPSPLPVGVGLPR
HHHHCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDPNAIRITFLGTSSGMPTRQRNVSGVAVQFPQRSEWWLFDCGEGTQHQLLRLDELRPS
CCCCEEEEEEEECCCCCCCHHCCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCCHH
QLRRIFITHMHGDHIYGLPGLLASCGLGSTPEHIDIYGPPGLEEYLKAVLRYSETRIPYG
HEEEEEEEEECCCEEECCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
FRVHTVETGLILQEPEYSVFCAPLDHRVPAFGYRVVEQDRPGSFNVAKAQADGIPFGPLY
EEEEEEECCEEEECCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCH
GQLKAGQSIIWQGRCFHGRDYVGDPIPGRKFSYCTDTIFCRNAVDLSRAADLVIHEATYA
HHHHCCCEEEEECEEECCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHEEEEECHHH
QADLELARRSKHSTAAMAAQVAAEAKAQALILTHFSPRYTPEAPITLEDLLAEAQAIFPN
HHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
TLLARDRLTYEIPRRSPSPLPVGVGLPR
HHHHCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA