Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 86608886

GI number: 86608886

Start: 1486359

End: 1487624

Strand: Direct

Name: argD [H]

Synonym: CYB_1419

Alternate gene names: 86608886

Gene position: 1486359-1487624 (Clockwise)

Preceding gene: 86608883

Following gene: 86608888

Centisome position: 48.79

GC content: 62.48

Gene sequence:

>1266_bases
ATGTCTCCTCTAACTTCGCCTCTTGCCAGTGCCCCCTCGGGATCCCCGACAACTGCCGAGCTGTTTGCCGAGCATGTGAT
GGCCACCTATGGGCGCTATCCCCTGACCTTGGTGCGCGGGCAGGGGTGTCGGGTTTGGGATGAGCAGGGGCGCGAGTACC
TGGACTTTGTGGCCGGCATTGCCACCTGTACCCTGGGGCATGCCCACCCGCTGTGGATTCAGGCGCTCACCGAGCAGGCA
CAACAGTTGCACCATGTTTCCAACCTTTACTACAACCAGCCGCAGGCACAACTGGCTCAATGGCTGACCCAGCACTCCTG
TGCCGACAAGGTGTTTTTCTGCAACTCAGGGGCGGAAGCCAATGAGGGAGCCATTAAGCTGGCTCGCAAGTATGCCCACA
CGGTGCGCGGGATCCAAGATCCGATGATCCTCACCGCCCATGCCAGCTTCCATGGCCGCACCCTGGCCACCATTACCGCC
ACCGGCCAGCCCAAATACCAAAAAGACTTTGCCCCTCTGGTGCCCGGCTTTGATTACGTTCCCTACAACGACATCGAGGG
CACAGCAGCGGTGTTGGAGCGCTGGGGCGAGCGGGTGTGTGCCGTGCTGTTGGAGCCGTTGCAGGGGGAAGGGGGGGTTG
TGCCGGGGGATCCCGCCTATTTTCAATGGTTGCGCCGGATCTGCAGCGAGCGGGGCATTCTGCTGATTTTGGATGAGGTG
CAGGTGGGCATGGGCCGTACTGGCATGCTGTGGGGCCACTGTAACCTGGGGGTGGAGCCGGATGTGTTCACCTTGGCCAA
GGGCCTGGCCGGTGGGATCCCCATCGGGGCCTTGTTGGCGAAAGACTTTTGCGCCGTGTTTCAGCCGGGGGATCACGCCA
GCACCTTTGGGGGCAACCCCTTGGCTTGTGCGGTGGGCCTGGCGGTTTGCCGCACGCTAATGTCGGAGAGTTTGGTTTGG
AATGCCCAGCAGACAGGGGTGTATCTGCGTCAGGGGCTGTCCCGCTTGGCGGAGCAGTTTCCGCAGCTCGTTGAGCAAGT
GCGGGGCTGGGGCCTGATTCAGGGCTTGGTGGTGCGCATCCCGGCGGCTGAAGTGGTCAAGGCAGCCATGGACTGCGGGC
TGTTGTTGGTGCCGGCAGGATCCCAGGTGGTGCGCTTTGTGCCCCCCTTGATCGTCACCCCGGCAGAAATTGACGCGGCT
CTAGCGATGTTGGCATCGGCTTTGCAAAGGTTGGCCGCCTCCCTTGGCCATTCCGGGGCAGCCTAG

Upstream 100 bases:

>100_bases
AGAATATCATCTCCAAAGCAGGGTGGTACACTCGAAACACGGCTTGCGCCAGCCCCAAAGCGCTCCGCGCCGCCAACACG
ACAGCAATCTTTTACCGGCC

Downstream 100 bases:

>100_bases
CCTCGCCAGACTTGCCGCAGAAATGCCTGCAACTGCTGTCGGGCAGGGAGCTCGTGGGGAGCGGGATCCCTTGCCTGTTT
CAGAAGGGGCAATACCTCCT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSPLTSPLASAPSGSPTTAELFAEHVMATYGRYPLTLVRGQGCRVWDEQGREYLDFVAGIATCTLGHAHPLWIQALTEQA
QQLHHVSNLYYNQPQAQLAQWLTQHSCADKVFFCNSGAEANEGAIKLARKYAHTVRGIQDPMILTAHASFHGRTLATITA
TGQPKYQKDFAPLVPGFDYVPYNDIEGTAAVLERWGERVCAVLLEPLQGEGGVVPGDPAYFQWLRRICSERGILLILDEV
QVGMGRTGMLWGHCNLGVEPDVFTLAKGLAGGIPIGALLAKDFCAVFQPGDHASTFGGNPLACAVGLAVCRTLMSESLVW
NAQQTGVYLRQGLSRLAEQFPQLVEQVRGWGLIQGLVVRIPAAEVVKAAMDCGLLLVPAGSQVVRFVPPLIVTPAEIDAA
LAMLASALQRLAASLGHSGAA

Sequences:

>Translated_421_residues
MSPLTSPLASAPSGSPTTAELFAEHVMATYGRYPLTLVRGQGCRVWDEQGREYLDFVAGIATCTLGHAHPLWIQALTEQA
QQLHHVSNLYYNQPQAQLAQWLTQHSCADKVFFCNSGAEANEGAIKLARKYAHTVRGIQDPMILTAHASFHGRTLATITA
TGQPKYQKDFAPLVPGFDYVPYNDIEGTAAVLERWGERVCAVLLEPLQGEGGVVPGDPAYFQWLRRICSERGILLILDEV
QVGMGRTGMLWGHCNLGVEPDVFTLAKGLAGGIPIGALLAKDFCAVFQPGDHASTFGGNPLACAVGLAVCRTLMSESLVW
NAQQTGVYLRQGLSRLAEQFPQLVEQVRGWGLIQGLVVRIPAAEVVKAAMDCGLLLVPAGSQVVRFVPPLIVTPAEIDAA
LAMLASALQRLAASLGHSGAA
>Mature_420_residues
SPLTSPLASAPSGSPTTAELFAEHVMATYGRYPLTLVRGQGCRVWDEQGREYLDFVAGIATCTLGHAHPLWIQALTEQAQ
QLHHVSNLYYNQPQAQLAQWLTQHSCADKVFFCNSGAEANEGAIKLARKYAHTVRGIQDPMILTAHASFHGRTLATITAT
GQPKYQKDFAPLVPGFDYVPYNDIEGTAAVLERWGERVCAVLLEPLQGEGGVVPGDPAYFQWLRRICSERGILLILDEVQ
VGMGRTGMLWGHCNLGVEPDVFTLAKGLAGGIPIGALLAKDFCAVFQPGDHASTFGGNPLACAVGLAVCRTLMSESLVWN
AQQTGVYLRQGLSRLAEQFPQLVEQVRGWGLIQGLVVRIPAAEVVKAAMDCGLLLVPAGSQVVRFVPPLIVTPAEIDAAL
AMLASALQRLAASLGHSGAA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=406, Percent_Identity=35.9605911330049, Blast_Score=266, Evalue=3e-71,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=38.0794701986755, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI13994255, Length=448, Percent_Identity=29.0178571428571, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=30.3827751196172, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=28.3018867924528, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=28.0285035629454, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=27.735368956743, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=426, Percent_Identity=23.943661971831, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI38679950, Length=426, Percent_Identity=23.943661971831, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI38679946, Length=426, Percent_Identity=23.943661971831, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1788044, Length=403, Percent_Identity=43.6724565756824, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=39.3483709273183, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI145693181, Length=421, Percent_Identity=35.6294536817102, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=33.9950372208437, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=34.5864661654135, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=29.6407185628743, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=35.2245862884161, Blast_Score=267, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=30.0683371298405, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=278, Percent_Identity=35.2517985611511, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71981843, Length=207, Percent_Identity=34.2995169082126, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=426, Percent_Identity=26.056338028169, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=475, Percent_Identity=26.3157894736842, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=35.25, Blast_Score=269, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6323470, Length=425, Percent_Identity=34.3529411764706, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=25.4117647058824, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=496, Percent_Identity=21.7741935483871, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=34.7150259067358, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI28574759, Length=430, Percent_Identity=30.9302325581395, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=30.3944315545244, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356575, Length=441, Percent_Identity=28.5714285714286, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281366494, Length=429, Percent_Identity=26.5734265734266, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24667139, Length=429, Percent_Identity=26.5734265734266, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24667143, Length=429, Percent_Identity=26.5734265734266, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45130; Mature: 44999

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLTSPLASAPSGSPTTAELFAEHVMATYGRYPLTLVRGQGCRVWDEQGREYLDFVAGI
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
ATCTLGHAHPLWIQALTEQAQQLHHVSNLYYNQPQAQLAQWLTQHSCADKVFFCNSGAEA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCC
NEGAIKLARKYAHTVRGIQDPMILTAHASFHGRTLATITATGQPKYQKDFAPLVPGFDYV
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCC
PYNDIEGTAAVLERWGERVCAVLLEPLQGEGGVVPGDPAYFQWLRRICSERGILLILDEV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECH
QVGMGRTGMLWGHCNLGVEPDVFTLAKGLAGGIPIGALLAKDFCAVFQPGDHASTFGGNP
HHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
LACAVGLAVCRTLMSESLVWNAQQTGVYLRQGLSRLAEQFPQLVEQVRGWGLIQGLVVRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
PAAEVVKAAMDCGLLLVPAGSQVVRFVPPLIVTPAEIDAALAMLASALQRLAASLGHSGA
CHHHHHHHHHCCCEEEECCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
A
C
>Mature Secondary Structure 
SPLTSPLASAPSGSPTTAELFAEHVMATYGRYPLTLVRGQGCRVWDEQGREYLDFVAGI
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
ATCTLGHAHPLWIQALTEQAQQLHHVSNLYYNQPQAQLAQWLTQHSCADKVFFCNSGAEA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCC
NEGAIKLARKYAHTVRGIQDPMILTAHASFHGRTLATITATGQPKYQKDFAPLVPGFDYV
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCHHHCCCCCCCCCCCC
PYNDIEGTAAVLERWGERVCAVLLEPLQGEGGVVPGDPAYFQWLRRICSERGILLILDEV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECH
QVGMGRTGMLWGHCNLGVEPDVFTLAKGLAGGIPIGALLAKDFCAVFQPGDHASTFGGNP
HHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCH
LACAVGLAVCRTLMSESLVWNAQQTGVYLRQGLSRLAEQFPQLVEQVRGWGLIQGLVVRI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
PAAEVVKAAMDCGLLLVPAGSQVVRFVPPLIVTPAEIDAALAMLASALQRLAASLGHSGA
CHHHHHHHHHCCCEEEECCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]