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The map label for this gene is arsA [H]

Identifier: 86608808

GI number: 86608808

Start: 1395356

End: 1397422

Strand: Direct

Name: arsA [H]

Synonym: CYB_1334

Alternate gene names: 86608808

Gene position: 1395356-1397422 (Clockwise)

Preceding gene: 86608807

Following gene: 86608809

Centisome position: 45.8

GC content: 60.91

Gene sequence:

>2067_bases
ATGTGGGAGGGGATCCCTTTGCAACTCAGTCGCGTTAACAGTGAGGAGCATTCCTGCCATCCTCTGCTCTTGGCTTCCCA
ACGCCTCTTGCTGTTCAGCGGCAAGGGAGGAGTGGGCAAAACAACCTTGACCTGCGCGCTGGCTCGCCAACTGGCCCAGG
TGGATCCCCAGCGCCGTCTGCTCCTGATGTCCACGGATCCCGCCCACTCGCTGGGGGACGTGCTGCAAATCTCGGTTACG
GATGTGGCCCAACCCTTGCCGGATCGCCCCAATTTGCAGGTGCGGGCTTTGCAAGCGGAGATTTTGTTGCAATCTTTTCG
GCAAACCTATGGGCCGGCCCTGGAGCTCATTGCCGAGCGGGGCAGTTGGTTTGGCCGAGAGGATCTGCTGCCGATCTGGG
ATTTAGCCTGGCCGGGGGTGGATGAGCTGATGGCGATTCTGGAGGTCAACCGGCTGCTGGCTGGGGAGGAGGTGGATACC
GTTATCTTGGACACGGCCCCCACCGGGCACACCCTGCGGCTGTTGGAGCTGCCCGACTTTTTGGATAATCTTCTGGCTGT
GTTTGCCACCTTTCAGGCCAAGCATCGGGAGATCGCCCAAGCCCTGACAGGCACCTATCGACCGGATGAGGCGGATGCGT
TTTTGGCCCAGTTGCAGGGGGAACTTGAGGGGGGCAAAGCCCGCTTGACCAATCCGGAGAGCACCTCTGCTTGGCTGGTG
ATGATCCCGGAGCAGTTGAGCGTGGCGGAAACCCGCCGCTTTTGTCAGCAACTGCAAAACCGCCGCGTGCCCATCGGCGG
TCTTCTGGTCAATCAGGTGCTGCTTGCAAGAGAGAATAACAGCCAACCTTCGCTGCCCGCTGCTCTCCCCTCTCCTCTCT
ACTCGGCGCGGCAACAGGAACAGGGGCGCGTGCTCAAAGCCCTGCAGGAGGAGCTGCCCGGATACTCTATCTGGGTCTGT
CCTTATCAACTACAGGAGCCGGTTGGGTTGGCGGCCCTGGATGAGCTGGTGCAGCAGCTTCGCCCCTTGCCAGAGGTGCT
GCTGGAGTTGGAAGGGATCCCAGAGCAAAAAGCAGAGAGCCAAGAGAAGAGAAAGTCTCTCTTCTCCACCCTCTTCCCTT
CCTTCAAGGGGATCCCGTCCCTACCGGATTTTTTGACCCAAGGGATCCGACTGGTGTTGGTGGGGGGCAAAGGGGGTGTG
GGCAAGACGACGGTGGCCGGGGCCCTGGCTTGGAACTTGGCCAAGCGCCATCCCGACAAGCAGCTCTTGCTGGTCTCCAT
CGATCCGGCTCACTCGTTGGGGGATCTGTTTCAGACGAAACTGGGTCAGGATCCCATTCCCCTGCTGCCCAACCTGCTGG
GGCAGGAGATCGATGCGGCGGCGGTGCTGGAGCAATTCCGGCAGGATTACCTGGAGGAGGTGGCGGCCATCTTGGCGGGG
GAGGGGACGGCAGGGGTGGAAGTCCAATACGACCCGCAGGCGTGGCGGCAACTGCTGCAGATGCCCCCACCCGGCTTGGA
TGAGGTGATGGCCCTGTTGAGTGTTCTCCGACAGGAGACGAGCGGGCAGTTTGACCTGGTGGTGCTGGACACGGCCCCCA
CAGGGCATCTCCTGCGGTTTCTGCAGATGCCCCAGGCTCTGGAGGGCTGGGTAAGCTTGGCCCTGAAGCTGTGGCTGAAA
TATCGGGATGTGGTGGGCAGGCCGGAATGGGCGCAGCGGATGCGGGAGCTCTTGGCCCAGGTGCGACAGCTCCGGCAGCA
GCTCCAGGATCCCCAGTTTGTTACCTTTATCCCCGTCTTTAACCCCGAGCAAGCAGTTCTGGCAGAAACCGAGCGTCTCT
TGGCGGAACTGGATGCTTTGGGGATCCCTCATCCCTACGCCGTTCTCAATCGAGTGTGGTTAGAGGATTCTACCCCCTTT
GGAGAGGCCCTCCGCCGTCGTCACCAGACTCTTCTGGCCCAGCTCCCCCAGCTATTTTCCCAGCAGGCCATCTTGACCAT
CCCCTTCCTACATCCTCCCAGCTTGGAGAATATCGGCTCCTACTTGTTCGCTCCTCAGGAGCCCTAA

Upstream 100 bases:

>100_bases
CTCCCGTACAAGCTCTTCCCATCCCGTCAGCGGTGCGGAGTACCTTTGCAGTGATCTAGAGCATCCCCAAGAGGGATCCA
GGCCAAAATAGGGGCGACCT

Downstream 100 bases:

>100_bases
CCTAGGGGTAGACCTTGCTCACCCAAAGCGTTATGGATCCCAAGTTGGAAGAACGCGCCCGCGAGCTGCGCACCCTGCTG
CAGAAGGCCAGCATTGCCTA

Product: arsenite-antimonite ArsAB efflux family transporter ATP-binding protein ArsAB

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MWEGIPLQLSRVNSEEHSCHPLLLASQRLLLFSGKGGVGKTTLTCALARQLAQVDPQRRLLLMSTDPAHSLGDVLQISVT
DVAQPLPDRPNLQVRALQAEILLQSFRQTYGPALELIAERGSWFGREDLLPIWDLAWPGVDELMAILEVNRLLAGEEVDT
VILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREIAQALTGTYRPDEADAFLAQLQGELEGGKARLTNPESTSAWLV
MIPEQLSVAETRRFCQQLQNRRVPIGGLLVNQVLLARENNSQPSLPAALPSPLYSARQQEQGRVLKALQEELPGYSIWVC
PYQLQEPVGLAALDELVQQLRPLPEVLLELEGIPEQKAESQEKRKSLFSTLFPSFKGIPSLPDFLTQGIRLVLVGGKGGV
GKTTVAGALAWNLAKRHPDKQLLLVSIDPAHSLGDLFQTKLGQDPIPLLPNLLGQEIDAAAVLEQFRQDYLEEVAAILAG
EGTAGVEVQYDPQAWRQLLQMPPPGLDEVMALLSVLRQETSGQFDLVVLDTAPTGHLLRFLQMPQALEGWVSLALKLWLK
YRDVVGRPEWAQRMRELLAQVRQLRQQLQDPQFVTFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWLEDSTPF
GEALRRRHQTLLAQLPQLFSQQAILTIPFLHPPSLENIGSYLFAPQEP

Sequences:

>Translated_688_residues
MWEGIPLQLSRVNSEEHSCHPLLLASQRLLLFSGKGGVGKTTLTCALARQLAQVDPQRRLLLMSTDPAHSLGDVLQISVT
DVAQPLPDRPNLQVRALQAEILLQSFRQTYGPALELIAERGSWFGREDLLPIWDLAWPGVDELMAILEVNRLLAGEEVDT
VILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREIAQALTGTYRPDEADAFLAQLQGELEGGKARLTNPESTSAWLV
MIPEQLSVAETRRFCQQLQNRRVPIGGLLVNQVLLARENNSQPSLPAALPSPLYSARQQEQGRVLKALQEELPGYSIWVC
PYQLQEPVGLAALDELVQQLRPLPEVLLELEGIPEQKAESQEKRKSLFSTLFPSFKGIPSLPDFLTQGIRLVLVGGKGGV
GKTTVAGALAWNLAKRHPDKQLLLVSIDPAHSLGDLFQTKLGQDPIPLLPNLLGQEIDAAAVLEQFRQDYLEEVAAILAG
EGTAGVEVQYDPQAWRQLLQMPPPGLDEVMALLSVLRQETSGQFDLVVLDTAPTGHLLRFLQMPQALEGWVSLALKLWLK
YRDVVGRPEWAQRMRELLAQVRQLRQQLQDPQFVTFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWLEDSTPF
GEALRRRHQTLLAQLPQLFSQQAILTIPFLHPPSLENIGSYLFAPQEP
>Mature_688_residues
MWEGIPLQLSRVNSEEHSCHPLLLASQRLLLFSGKGGVGKTTLTCALARQLAQVDPQRRLLLMSTDPAHSLGDVLQISVT
DVAQPLPDRPNLQVRALQAEILLQSFRQTYGPALELIAERGSWFGREDLLPIWDLAWPGVDELMAILEVNRLLAGEEVDT
VILDTAPTGHTLRLLELPDFLDNLLAVFATFQAKHREIAQALTGTYRPDEADAFLAQLQGELEGGKARLTNPESTSAWLV
MIPEQLSVAETRRFCQQLQNRRVPIGGLLVNQVLLARENNSQPSLPAALPSPLYSARQQEQGRVLKALQEELPGYSIWVC
PYQLQEPVGLAALDELVQQLRPLPEVLLELEGIPEQKAESQEKRKSLFSTLFPSFKGIPSLPDFLTQGIRLVLVGGKGGV
GKTTVAGALAWNLAKRHPDKQLLLVSIDPAHSLGDLFQTKLGQDPIPLLPNLLGQEIDAAAVLEQFRQDYLEEVAAILAG
EGTAGVEVQYDPQAWRQLLQMPPPGLDEVMALLSVLRQETSGQFDLVVLDTAPTGHLLRFLQMPQALEGWVSLALKLWLK
YRDVVGRPEWAQRMRELLAQVRQLRQQLQDPQFVTFIPVFNPEQAVLAETERLLAELDALGIPHPYAVLNRVWLEDSTPF
GEALRRRHQTLLAQLPQLFSQQAILTIPFLHPPSLENIGSYLFAPQEP

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=310, Percent_Identity=29.3548387096774, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17557003, Length=291, Percent_Identity=29.2096219931272, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320103, Length=353, Percent_Identity=29.1784702549575, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24586297, Length=334, Percent_Identity=29.0419161676647, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016300
- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 76472; Mature: 76472

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWEGIPLQLSRVNSEEHSCHPLLLASQRLLLFSGKGGVGKTTLTCALARQLAQVDPQRRL
CCCCCCCCCEECCCCCCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCE
LLMSTDPAHSLGDVLQISVTDVAQPLPDRPNLQVRALQAEILLQSFRQTYGPALELIAER
EEEECCCCHHHHHHHEEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GSWFGREDLLPIWDLAWPGVDELMAILEVNRLLAGEEVDTVILDTAPTGHTLRLLELPDF
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHH
LDNLLAVFATFQAKHREIAQALTGTYRPDEADAFLAQLQGELEGGKARLTNPESTSAWLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
MIPEQLSVAETRRFCQQLQNRRVPIGGLLVNQVLLARENNSQPSLPAALPSPLYSARQQE
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QGRVLKALQEELPGYSIWVCPYQLQEPVGLAALDELVQQLRPLPEVLLELEGIPEQKAES
HHHHHHHHHHHCCCCEEEECCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
QEKRKSLFSTLFPSFKGIPSLPDFLTQGIRLVLVGGKGGVGKTTVAGALAWNLAKRHPDK
HHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
QLLLVSIDPAHSLGDLFQTKLGQDPIPLLPNLLGQEIDAAAVLEQFRQDYLEEVAAILAG
EEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EGTAGVEVQYDPQAWRQLLQMPPPGLDEVMALLSVLRQETSGQFDLVVLDTAPTGHLLRF
CCCCCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
LQMPQALEGWVSLALKLWLKYRDVVGRPEWAQRMRELLAQVRQLRQQLQDPQFVTFIPVF
HHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
NPEQAVLAETERLLAELDALGIPHPYAVLNRVWLEDSTPFGEALRRRHQTLLAQLPQLFS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
QQAILTIPFLHPPSLENIGSYLFAPQEP
CCCEEEEECCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MWEGIPLQLSRVNSEEHSCHPLLLASQRLLLFSGKGGVGKTTLTCALARQLAQVDPQRRL
CCCCCCCCCEECCCCCCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCE
LLMSTDPAHSLGDVLQISVTDVAQPLPDRPNLQVRALQAEILLQSFRQTYGPALELIAER
EEEECCCCHHHHHHHEEEHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
GSWFGREDLLPIWDLAWPGVDELMAILEVNRLLAGEEVDTVILDTAPTGHTLRLLELPDF
CCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHH
LDNLLAVFATFQAKHREIAQALTGTYRPDEADAFLAQLQGELEGGKARLTNPESTSAWLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEE
MIPEQLSVAETRRFCQQLQNRRVPIGGLLVNQVLLARENNSQPSLPAALPSPLYSARQQE
ECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QGRVLKALQEELPGYSIWVCPYQLQEPVGLAALDELVQQLRPLPEVLLELEGIPEQKAES
HHHHHHHHHHHCCCCEEEECCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
QEKRKSLFSTLFPSFKGIPSLPDFLTQGIRLVLVGGKGGVGKTTVAGALAWNLAKRHPDK
HHHHHHHHHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
QLLLVSIDPAHSLGDLFQTKLGQDPIPLLPNLLGQEIDAAAVLEQFRQDYLEEVAAILAG
EEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
EGTAGVEVQYDPQAWRQLLQMPPPGLDEVMALLSVLRQETSGQFDLVVLDTAPTGHLLRF
CCCCCCEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHH
LQMPQALEGWVSLALKLWLKYRDVVGRPEWAQRMRELLAQVRQLRQQLQDPQFVTFIPVF
HHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
NPEQAVLAETERLLAELDALGIPHPYAVLNRVWLEDSTPFGEALRRRHQTLLAQLPQLFS
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHC
QQAILTIPFLHPPSLENIGSYLFAPQEP
CCCEEEEECCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9847077; 11016950 [H]