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The map label for this gene is mtnN [H]

Identifier: 86608758

GI number: 86608758

Start: 1337729

End: 1338484

Strand: Direct

Name: mtnN [H]

Synonym: CYB_1283

Alternate gene names: 86608758

Gene position: 1337729-1338484 (Clockwise)

Preceding gene: 86608752

Following gene: 86608761

Centisome position: 43.91

GC content: 61.64

Gene sequence:

>756_bases
ATGGAATCTCCATCTCATCCCCCCCAGAAAGCCATCGGCATTCTTGGAGCCCTGCCCGAGGAAGTGGCCATGCTCACCGC
AGCAATGGAAACCTGCTCCATCCATACCCATCTGGGGCGACAGTTCCACCAGGGATCCCTGGCGGGGCAACCGGTGGTGG
TGGTACAAGGTGGGGTGGGCAAGGTGCGGGCGGCAACCACAGCGGCTTTGTTGGTGGCCCATTTCCCTTTGCAGGGGATC
ATTTTTACCGGTGTGGCCGGGGCCTTGGCCGATCACCTGCACATGGGAGATGTGGTGCTGGCCCATGCGGCGATCGAGCA
CGACTTCGGCACCGGGCGTCCAGAGGGCTTTGTTTTGGGGATCGACTTTATCCCAGAGCTGCGCCACCCACTGGCCGAGG
CCGATAGCGCTCTCTACGACCTGATCGTGGCCCACCCCGAGCGGATCCCTCTCCACCCCCTACAAGGCCGGGATCCCGTC
ATTCATCAAGGCTTGGTGGCCACCGGCGATGTGTTTGTGGCCGACGCAGACCTACGCCGACAAATCCGAGAACGCACCGG
CGCTTTGGTGGTGGAGATGGAGGGGGCAGCCGTGGTGCGAGTAGCGCAAGAAGCCGGGATCCCTTGTTTGCTGGTGCGCT
CGGTCAGCGATGCAGGGGACGATACGGATTTCTTGAGCTTTTTTCAAACAGCAGCGCTCAACTCAGCAGCAGTTGTCCGC
ACCATCCTGCAAAACCTGCCCCCCTCCTTGCCTTAG

Upstream 100 bases:

>100_bases
GGTTCACTAAGTGGCCGGACAGGTGAGGGCAAGCGATCCCCCCCGCCAACTGGAGAGAGAGCCTGTTCAAAAGTCTTTCG
AAGAACCTGAGGGAAGCTCT

Downstream 100 bases:

>100_bases
CCCAAGTGCGCAGATCCCCTCCTCTAGCGCAAAAGACGCAAAAGAGGAGTTGGGCATGGTTGCGTTCGCGTCAGTTGTTC
ATCTCCCGCTCCAGCTTGGC

Product: MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MESPSHPPQKAIGILGALPEEVAMLTAAMETCSIHTHLGRQFHQGSLAGQPVVVVQGGVGKVRAATTAALLVAHFPLQGI
IFTGVAGALADHLHMGDVVLAHAAIEHDFGTGRPEGFVLGIDFIPELRHPLAEADSALYDLIVAHPERIPLHPLQGRDPV
IHQGLVATGDVFVADADLRRQIRERTGALVVEMEGAAVVRVAQEAGIPCLLVRSVSDAGDDTDFLSFFQTAALNSAAVVR
TILQNLPPSLP

Sequences:

>Translated_251_residues
MESPSHPPQKAIGILGALPEEVAMLTAAMETCSIHTHLGRQFHQGSLAGQPVVVVQGGVGKVRAATTAALLVAHFPLQGI
IFTGVAGALADHLHMGDVVLAHAAIEHDFGTGRPEGFVLGIDFIPELRHPLAEADSALYDLIVAHPERIPLHPLQGRDPV
IHQGLVATGDVFVADADLRRQIRERTGALVVEMEGAAVVRVAQEAGIPCLLVRSVSDAGDDTDFLSFFQTAALNSAAVVR
TILQNLPPSLP
>Mature_251_residues
MESPSHPPQKAIGILGALPEEVAMLTAAMETCSIHTHLGRQFHQGSLAGQPVVVVQGGVGKVRAATTAALLVAHFPLQGI
IFTGVAGALADHLHMGDVVLAHAAIEHDFGTGRPEGFVLGIDFIPELRHPLAEADSALYDLIVAHPERIPLHPLQGRDPV
IHQGLVATGDVFVADADLRRQIRERTGALVVEMEGAAVVRVAQEAGIPCLLVRSVSDAGDDTDFLSFFQTAALNSAAVVR
TILQNLPPSLP

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=250, Percent_Identity=32, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 26435; Mature: 26435

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPSHPPQKAIGILGALPEEVAMLTAAMETCSIHTHLGRQFHQGSLAGQPVVVVQGGVG
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
KVRAATTAALLVAHFPLQGIIFTGVAGALADHLHMGDVVLAHAAIEHDFGTGRPEGFVLG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDFIPELRHPLAEADSALYDLIVAHPERIPLHPLQGRDPVIHQGLVATGDVFVADADLRR
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEECCCEEEECHHHHH
QIRERTGALVVEMEGAAVVRVAQEAGIPCLLVRSVSDAGDDTDFLSFFQTAALNSAAVVR
HHHHHHCEEEEEECCCEEEEEHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHH
TILQNLPPSLP
HHHHHCCCCCC
>Mature Secondary Structure
MESPSHPPQKAIGILGALPEEVAMLTAAMETCSIHTHLGRQFHQGSLAGQPVVVVQGGVG
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
KVRAATTAALLVAHFPLQGIIFTGVAGALADHLHMGDVVLAHAAIEHDFGTGRPEGFVLG
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
IDFIPELRHPLAEADSALYDLIVAHPERIPLHPLQGRDPVIHQGLVATGDVFVADADLRR
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEECCCEEEECHHHHH
QIRERTGALVVEMEGAAVVRVAQEAGIPCLLVRSVSDAGDDTDFLSFFQTAALNSAAVVR
HHHHHHCEEEEEECCCEEEEEHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHH
TILQNLPPSLP
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]