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The map label for this gene is barA [H]

Identifier: 86608466

GI number: 86608466

Start: 1021950

End: 1023713

Strand: Reverse

Name: barA [H]

Synonym: CYB_0987

Alternate gene names: 86608466

Gene position: 1023713-1021950 (Counterclockwise)

Preceding gene: 86608467

Following gene: 86608465

Centisome position: 33.6

GC content: 59.47

Gene sequence:

>1764_bases
ATGGTGGTCTCCTCCCCCATGGGTGTGCTCCGACCCACTCCGATGTTCTACACGCAGGATCGCCAGAGGCGCTTCTGGAG
TTTTTACTGGGAAGATGCCGAGAAGTACGGCATCCACCCTCAGCACATCGTGAGCGGACAGCAAGTTTGGGAGGTGACCA
ACGCCGGGGAGTATGAGGCTAAGCTCAACCAGGTCTTTGCAAGCGGGGATCCCCTCTCCTACGAATGTCAGGTGCTCTCG
CCCCGCTACAAGTTGCATCTGCATCTTTCTCTCAACCCTGTACGGGACATGGAAGGGGAGGTGGTGGCGGTTGCGGCAGT
GGGCAAGTTGCTGGGGGCCACGCCTTTTGCGCTGGCCGGAGGAGCCAGCAGCCCCAACAGCCAGCCCCATCCTGTCCTGG
CCGACCCGGTACAGGGGATCACGACGCAGTTGGTGCGCAACATCCGGCATTCCCTGGATATCCGGCAACTGTGCCAGCAG
ACCGTGGAGCAGTTGGGGCAACTGTTTGAGGTAGATCGCTGCCTGATGGCCCTCTACGAGGTGGGGCAAGACTCCCTCAC
GGTCAATGCCGAGTACCGCCGCCATCCTGGGGATCCCTCCCTGCTCCACCAGACCCTGAAGCTGGCAGATTACCCCCATT
TGTTGCAGGCCCTCAGACAGGAAGAACCGGTGGAGGCGGGGCGACATCTGGCCATTGCCATGTCTTACCAGGGCTACGCC
AACAGCCTGCTCTGGCTGGAAATGCTGGATCCGAATAGGGTTCCTGTTTGGCAGCCAAGCCACATTCAGGTACTCCAGAG
CATTGCCACCTACCTGGGCGCGGCCATTGCCCACGCCATTTTGCTGGATCAAAGTCGCCAACTGGCAACCCGCTTGCAGT
TAGCCAACCAAACTCTGCGTCAGAAAAATAAGGAGCTGGAGCAGGCCCGTGCCCAAGCGGAATCGGCCAACCAACTGAAA
AGCCAATTCCTGGCCAACACCTCCCACGAGCTGCGCACCCCTCTCAACGGGATCATCGGCTTTATCAAGCTGGTGCTGGA
CGGGATGGCCGAAAACCGCGAAGAGGAGCTGGACTTTTTGCAAGAGGCCTATCGCTCTGCCCTGCACCTGCTGGCCCTAA
TCAACGATGTGCTGGATATCGCCAAGATCGAGGCGGGCAAAATGCAGTTGGAGTTCCAGCCCTGCGACCTGCGAGCTTTG
TTTAAGGATGTGGAGGCCAAGACTAGCCTGCAGGCCAGCCAAAAGGGCCTACAACTGAGCTTCCACCTGCCCAACACCTC
GGATCAGATTTTGCTCTTGGGCGATTACCAACGCCTGTTGCAGGTGATGCTCAATTTGGTGGGGAATGCCATCAAGTTTA
CCCCCAAAGGCTCAGTAACCGTGCGGGCGGATATCCTGCCCGGCAACCCAGGTTTGGCCCGCATCCGCGTCATCGACACC
GGGATCGGGGTATCGCTGGAAAAGCAGCAGAAGCTGTTTCAGGCCTTCACACAGGTGGATGGTTCCACCACCCGCCAATA
TGGGGGGACGGGCTTGGGCCTGGCCATCAGCCAACGCCTGGTGGAGGCGATGGGAGGGGAAATCAATTTCTACAGCCTGG
GCGAAGGGCTGGGATCCACCGTCACCTTTACGGTGCCCCTCTACCGCAAGCCGCTCCTGAGCGGGGATCCGAACCCAGAG
GCGCTCCCTGCTCAACCCGCCCGAGATAGACCTGAGGATGCGGATCCCACCTTGATTTCTGTTCCCAACTCAGTCCAGCG
ATGA

Upstream 100 bases:

>100_bases
TCAACAAGGACTCTGCCCCACTAACCCGCCCGGCCTCTGATCCGGCCAGCCCGGCTTCCTCTGGAAAAACCTGAGTTTTG
GCCTGTGTTCCCCTAACGCA

Downstream 100 bases:

>100_bases
CCCACCCGGCCATTTCTCCTTCAACCGCTCTGGGTACCGCTCGGTTGCCCTATCCTCGTAAACGGTTTGGTCAGCATTGG
CTCAAGGATCCCGCTGTTCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MVVSSPMGVLRPTPMFYTQDRQRRFWSFYWEDAEKYGIHPQHIVSGQQVWEVTNAGEYEAKLNQVFASGDPLSYECQVLS
PRYKLHLHLSLNPVRDMEGEVVAVAAVGKLLGATPFALAGGASSPNSQPHPVLADPVQGITTQLVRNIRHSLDIRQLCQQ
TVEQLGQLFEVDRCLMALYEVGQDSLTVNAEYRRHPGDPSLLHQTLKLADYPHLLQALRQEEPVEAGRHLAIAMSYQGYA
NSLLWLEMLDPNRVPVWQPSHIQVLQSIATYLGAAIAHAILLDQSRQLATRLQLANQTLRQKNKELEQARAQAESANQLK
SQFLANTSHELRTPLNGIIGFIKLVLDGMAENREEELDFLQEAYRSALHLLALINDVLDIAKIEAGKMQLEFQPCDLRAL
FKDVEAKTSLQASQKGLQLSFHLPNTSDQILLLGDYQRLLQVMLNLVGNAIKFTPKGSVTVRADILPGNPGLARIRVIDT
GIGVSLEKQQKLFQAFTQVDGSTTRQYGGTGLGLAISQRLVEAMGGEINFYSLGEGLGSTVTFTVPLYRKPLLSGDPNPE
ALPAQPARDRPEDADPTLISVPNSVQR

Sequences:

>Translated_587_residues
MVVSSPMGVLRPTPMFYTQDRQRRFWSFYWEDAEKYGIHPQHIVSGQQVWEVTNAGEYEAKLNQVFASGDPLSYECQVLS
PRYKLHLHLSLNPVRDMEGEVVAVAAVGKLLGATPFALAGGASSPNSQPHPVLADPVQGITTQLVRNIRHSLDIRQLCQQ
TVEQLGQLFEVDRCLMALYEVGQDSLTVNAEYRRHPGDPSLLHQTLKLADYPHLLQALRQEEPVEAGRHLAIAMSYQGYA
NSLLWLEMLDPNRVPVWQPSHIQVLQSIATYLGAAIAHAILLDQSRQLATRLQLANQTLRQKNKELEQARAQAESANQLK
SQFLANTSHELRTPLNGIIGFIKLVLDGMAENREEELDFLQEAYRSALHLLALINDVLDIAKIEAGKMQLEFQPCDLRAL
FKDVEAKTSLQASQKGLQLSFHLPNTSDQILLLGDYQRLLQVMLNLVGNAIKFTPKGSVTVRADILPGNPGLARIRVIDT
GIGVSLEKQQKLFQAFTQVDGSTTRQYGGTGLGLAISQRLVEAMGGEINFYSLGEGLGSTVTFTVPLYRKPLLSGDPNPE
ALPAQPARDRPEDADPTLISVPNSVQR
>Mature_587_residues
MVVSSPMGVLRPTPMFYTQDRQRRFWSFYWEDAEKYGIHPQHIVSGQQVWEVTNAGEYEAKLNQVFASGDPLSYECQVLS
PRYKLHLHLSLNPVRDMEGEVVAVAAVGKLLGATPFALAGGASSPNSQPHPVLADPVQGITTQLVRNIRHSLDIRQLCQQ
TVEQLGQLFEVDRCLMALYEVGQDSLTVNAEYRRHPGDPSLLHQTLKLADYPHLLQALRQEEPVEAGRHLAIAMSYQGYA
NSLLWLEMLDPNRVPVWQPSHIQVLQSIATYLGAAIAHAILLDQSRQLATRLQLANQTLRQKNKELEQARAQAESANQLK
SQFLANTSHELRTPLNGIIGFIKLVLDGMAENREEELDFLQEAYRSALHLLALINDVLDIAKIEAGKMQLEFQPCDLRAL
FKDVEAKTSLQASQKGLQLSFHLPNTSDQILLLGDYQRLLQVMLNLVGNAIKFTPKGSVTVRADILPGNPGLARIRVIDT
GIGVSLEKQQKLFQAFTQVDGSTTRQYGGTGLGLAISQRLVEAMGGEINFYSLGEGLGSTVTFTVPLYRKPLLSGDPNPE
ALPAQPARDRPEDADPTLISVPNSVQR

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=44.9056603773585, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=39.2405063291139, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=36.0655737704918, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI87081816, Length=296, Percent_Identity=35.472972972973, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693157, Length=296, Percent_Identity=37.1621621621622, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=31.9838056680162, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=31.8965517241379, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=28.8617886178862, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=327, Percent_Identity=24.4648318042813, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=31.25, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=250, Percent_Identity=28.8, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=178, Percent_Identity=36.5168539325843, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65062; Mature: 65062

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSSPMGVLRPTPMFYTQDRQRRFWSFYWEDAEKYGIHPQHIVSGQQVWEVTNAGEYEA
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHEEECCCCCHHH
KLNQVFASGDPLSYECQVLSPRYKLHLHLSLNPVRDMEGEVVAVAAVGKLLGATPFALAG
HHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCEEEC
GASSPNSQPHPVLADPVQGITTQLVRNIRHSLDIRQLCQQTVEQLGQLFEVDRCLMALYE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQDSLTVNAEYRRHPGDPSLLHQTLKLADYPHLLQALRQEEPVEAGRHLAIAMSYQGYA
CCCCCEEEEEHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCEEEEEEECCCCC
NSLLWLEMLDPNRVPVWQPSHIQVLQSIATYLGAAIAHAILLDQSRQLATRLQLANQTLR
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
QKNKELEQARAQAESANQLKSQFLANTSHELRTPLNGIIGFIKLVLDGMAENREEELDFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHH
QEAYRSALHLLALINDVLDIAKIEAGKMQLEFQPCDLRALFKDVEAKTSLQASQKGLQLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEE
FHLPNTSDQILLLGDYQRLLQVMLNLVGNAIKFTPKGSVTVRADILPGNPGLARIRVIDT
EECCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCEEEEEEEEC
GIGVSLEKQQKLFQAFTQVDGSTTRQYGGTGLGLAISQRLVEAMGGEINFYSLGEGLGST
CCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCE
VTFTVPLYRKPLLSGDPNPEALPAQPARDRPEDADPTLISVPNSVQR
EEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHCCC
>Mature Secondary Structure
MVVSSPMGVLRPTPMFYTQDRQRRFWSFYWEDAEKYGIHPQHIVSGQQVWEVTNAGEYEA
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHEEECCCCCHHH
KLNQVFASGDPLSYECQVLSPRYKLHLHLSLNPVRDMEGEVVAVAAVGKLLGATPFALAG
HHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHCCCCCEEEC
GASSPNSQPHPVLADPVQGITTQLVRNIRHSLDIRQLCQQTVEQLGQLFEVDRCLMALYE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGQDSLTVNAEYRRHPGDPSLLHQTLKLADYPHLLQALRQEEPVEAGRHLAIAMSYQGYA
CCCCCEEEEEHHCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCHHCCCEEEEEEECCCCC
NSLLWLEMLDPNRVPVWQPSHIQVLQSIATYLGAAIAHAILLDQSRQLATRLQLANQTLR
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
QKNKELEQARAQAESANQLKSQFLANTSHELRTPLNGIIGFIKLVLDGMAENREEELDFL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHH
QEAYRSALHLLALINDVLDIAKIEAGKMQLEFQPCDLRALFKDVEAKTSLQASQKGLQLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEE
FHLPNTSDQILLLGDYQRLLQVMLNLVGNAIKFTPKGSVTVRADILPGNPGLARIRVIDT
EECCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCEEEEEEEEC
GIGVSLEKQQKLFQAFTQVDGSTTRQYGGTGLGLAISQRLVEAMGGEINFYSLGEGLGST
CCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCE
VTFTVPLYRKPLLSGDPNPEALPAQPARDRPEDADPTLISVPNSVQR
EEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]